Liste des publications

  • Article • Stability of fecal calprotectin extracts using the Diasorin® kit [Full paper ]

    B. Billet, L. Choisnard, P. Faure, D. Guicherd, E. Cussigh, E. Peyrin, C. Ravelet, B. Chovelon

    Clin. Chem. Lab. Med. 2024, 62, e13–e15

  • Article • Iodinated Organic Molecule as Tag for Inductively Coupled Plasma-Mass Spectrometry Aptamer Assays [Full paper ]

    B. Billet, B. Chovelon, E. M. McConnell, D. André, L. Puillet-Anselme, E. Fiore, P. Faure, C. Ravelet, M. C. DeRosa, E. Peyrin

    Talanta, 2024, 267, 125107

  • Article • Aurones and derivatives as promising New Delhi metallo-β-lactamase (NDM-1) inhibitors [Full paper ]

    Jérémy Caburet, Federica Verdirosa, Matis Moretti, Brayan Roulier, Giorgia Simoncelli, Romain Haudecoeur, Somayeh Ghazi, Hélène Jamet, Jean-Denis Docquier, Benjamin Boucherle, Marine Peuchmaur

    Bioorganic & Medicinal Chemistry 2024 97, 117559

  • Article • Preparative supercritical fluid chromatography as green purification methodology [Full paper ]

    E. Peyrin, E. Lipka

    Trends Anal. Chem., 2024, 171, 117505

  • Article • Expanding Chemical Frontiers: Approaches for Generating Diverse and Bioactive Natural Product-Like Compounds Libraries from Extracts [Full paper ]

    Aurélien Beato, Romain Haudecoeur, Benjamin Boucherle and Marine Peuchmaur

    Chem. Eur. J. 2024, e202304166

  • Article • Non-Competitive Determination of Small Analytes by Sandwich-type Lateral Flow Assay based on Aptamer Kissing Complex [Full paper ]

    B. Chovelon, V. Ranganathan, S. Srinivasan, E. McConnell, P. Faure, E. Fiore, C. Ravelet, E. Peyrin, M. DeRosa

    Anal. Chem. 2024, 96, 18, 6875-6880

  • Article • Design and synthesis of 4-amino-2′,4′-dihydroxyindanone derivatives as potent inhibitors of tyrosinase and melanin biosynthesis in human melanoma cells [Full paper ]

    L. M. Lazinski, M. Beaumet, B. Roulier, R. Gay, G. Royal, M. Maresca, R. Haudecoeur

  • Article • Validation of HPLC and TLC analytical methods to determine radiochemical purity of 99mTc-cAbVCAM1-5, a new experimental radiotracer 

    Leenhardt, J. Mutin, J. Choisnard, L. Orhon, P. Lassiaz, M. Bacot, S. Ahmadi, M. De Leiris, N. Djaileb, L. Broisat, A. Ghezzi, C. Bedouch, P. Brunet, M. D.

  • Article • Comparative study of production and control processes of parenteral nutritional admixtures in neonatology [Full paper ]

    Bosson, A. Durand, M. Mazet, R. Jouannet-Romaszko, M. Chennell, P. Mounsef, F. Quessada, T. Choisnard, L. Bedouch, P.

    Ann Pharm Fr, 2024, 82,306-317

  • Article • Peptide-based CE-SELEX enables convenient isolation of aptamers specifically recognizing CD20-expressing cells 

    J. Cossu, C. Ravelet, V. Martel-Frachet, E. Peyrin, D. Boturyn

    Bioorg. Med. Chem. 2024, doi.org/10.1016/j.bmc.2024.117831

  • Article • Comparative metabolomics reveals how the severity of predation by the invasive insect Cydalima perspectalis modulates the metabolism re–orchestration of native Buxus sempervirens [Full paper ]

    A. E. Hay, C. Deborde, T. Dussarrat, A. Moing, A. Millery, T. P. T. Hoang, D. Touboul, M. Rey, L. Ledru, S. Ibanez, P. Petriacq, C. Vanhaverbeke & C. Gallet

  • Article • Prediction of the structure of polymer-coated cardboards produced by thermocompression using I-optimal design of experiment [Full paper ]

    Allison Vercasson, Luc Choisnard, Elsa Lamberet, Sébastien Gaucel, Valérie Guillard, Hélène Angellier-Coussy

    Materials Today Communications, 2024,41, 110411

  • Article • Design of hyaluronan-based dopant for conductive and resorbable PEDOT ink [Full paper ]

    M. Leprince, P. Mailley, L. Choisnard, R. Auzély-Velty, I. Texier

    Carbohydr. Polym. 2023, 301

  • Article • Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use [Full paper ]

    R. Goutaudier, F. Joly, D. Mallet, M. Bartolomucci, D. Guicherd, C. Carcenac, F. Vossier, T. Dufourd, S. Boulet, C. Deransart, B. Chovelon, S. Carnicella

    Mol. Psychiatry 2023, 28, 463 74

  • Article • Nile blue as reporter dye in salt aggregation based-colorimetric aptasensors for peptide, small molecule and metal ion detection [Full paper ]

    B. Chovelon, E. Peyrin, M. Ragot, N. Salem, T. Giang Nguyen, B. Auvray, M. Henry, M-A Petrillo, E. Fiore, Q. Bessy, P. Faure, C. Ravelet

    Anal. Chim. Acta, 2023, 1243, 340840

  • Article • Optimizing chemistry at the surface of prodrugloaded cellulose nanofibrils with MAS-DNP [Full paper ]

    A. Kumar, B. Watbled, I. Baussanne, S. Hediger, M. Demeunynck, G. De Paëpe

    Commun. Chem. 2023, 6, 1 13

  • Article • Bacterial survival in radiopharmaceutical solutions: a critical impact on current practices [Full paper ]

    J. Leenhardt, L. Choisnard, M. Plasse, V. Ardisson, N. de Leiris, L. Djaileb, P. Bedouch, M.-D. Brunet

    EJNMMI Radiopharm. Chem. 2023

  • Article • Toward non-factor therapy in hemophilia: an antithrombin insensitive Gla-domainless factor Xa as tissue factor pathway inhibitor bait [Full paper ]

    M.-C. Dagher, A. Ersayin, L. Seyve, M. Castellan, C. Moreau, L. Choisnard, N. Thielens, R. Marlu, B. Polack, A. Thomas

    Res. Practice Thrombosis Haemostasis 2023, 7, 102175

  • Article • Investigation of Chemical Composition and Biological Activities of Ajuga pyramidalis—Isolation of Iridoids and Phenylethanoid Glycosides [Full paper ]

    A. Gori, B. Boucherle, A. Rey, M. Rome, C. Barette, E. Soleilhac, C. Philouze, M.-O. Fauvarque, N. Fuzzati, M. Peuchmaur

    Metabolites 2023, 13, 128

  • Article • Epstein-Barr Virus Encephalitis: A Review of Case Reports from the Last 25 Years [Full paper ]

    M. Peuchmaur, J. Voisin, M. Vaillant, A. Truffot, J. Lupo, P. Morand, M. Le Maréchal, R. Germi

    Microorganisms 2023, 11, 12, 2825

  • Article • Resorcinol-based hemiindigoid derivatives as human tyrosinase inhibitors and melanogenesis suppressors in human melanoma cells  [Full paper ]

    B. Roulier, I. Rush, L. M. Lazinski, B. Pérès, H. Olleik, G. Royal, A. Fishman, M. Maresca, R. Haudecoeur

    Eur. J. Med. Chem. 2023, 246, 114972

  • Article • Catechol-mimicking transition-state analogues as non-oxidizable inhibitors of tyrosinases  [Full paper ]

    M. Beaumet, L. M. Lazinski, M. Maresca, R. Haudecoeur

    Eur. J. Med. Chem. 2023, 259, 115672

  • Article • Total Synthesis of the Natural (−)-205B Alkaloid and Its Activity toward Α7 nAChRs  [Full paper ]

    S. Mazeh, M. D. Garcia-Fernandez, B. Pelletier, C. Moreau, P. Delair

    Microorganisms 2023, 11, 2825

  • Article • Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability  [Full paper ]

    P. Lagardère, R. Mustière, N. Amanzougaghene, S. Hutter, M. Casanova, J.-F. Franetich, S. Tajeri, A. Malzert-Fréon, S. Corvaisier, M. Since, N. Azas, P. Vanelle, P. Verhaeghe, N. Primas, D. Mazier, N. Masurier, V. Liwsowski

    Eur. J. Med. Chem. 2023, 261, 115873

  • Article • New antiplasmodial 4-amino-thieno[3,2-d]pyrimidines with improved intestinal permeability and microsomal stability  

    P. Lagardère, R. Mustière, N. Amanzougaghene, S. Hutter, M. Casanova, J.-F. Franetich, S. Tajeri, A. Malzert-Fréon, S. Corvaisier, N. Azas, P. Vanelle, P. Verhaeghe, N. Primas, D. Mazier, N. Masurier, V. Lisowski

    10.1016/j.ejmech.2023.115115

  • Article • Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery  [Full paper ]

    G. Valdameri, D. H. Kita, J. de Paula Dutra, D. L. Gomes, A. K. Tonduru, T. Kronenberger, B. Gavinho, R. Izadora Volpato, M. Mazetto de Cravalho, B. Pérès, I. F. Zattoni, F. Gomes de Moraes Rego, G. Picheth, R. Aves de Freitas, A. Poso, S. V. Ambudkar

    Pharmaceutics 2023, 15, 1259

  • Article • Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design  [Full paper ]

    L. Goracci, A. Nurisso, E. Roussel, B. Pérès, V. Chaptal, P. Falson, C. Marminon, J. Jose, M. Le Borgne, A. Boumendjel

    Eur. J. Med. Chem. 2023, 248, 115070

  • Article • Deficient Pseudomonas aeruginosa in MlaA/VacJ outer membrane lipoprotein shows decrease in rhamnolipids secretion, motility, and biofilm formation, and increase in fluoroquinolones susceptibility and innate immune response  [Full paper ]

    M. Kaur, J. M. Buyck, F. Goormaghtigh, J. -L. Decout, N. Mozaheb, M. -P. Mingeot-Leclercq

    Res. Microbiol. 2023, 174, 104132

  • Article • SCF-ChemBio: Chemical Biology Tour de France [Full paper ]

    M. Lopez, Y.-S. Wong, C. Biot, B. Vauzeilles

    ChemBioChem 2023, 24, e202300075

  • Article • Exposure to a Mixture of Non-Persistent Environmental Chemicals and Neonatal Thyroid Function in a Cohort with Improved Exposure Assessment  [Full paper ]

    O. Coiffier, D. Nakiwala, M. Rolland, A. Malatesta, S. Lyon-Caen, B. Chovelon, P. Faure, A. S. Gauchez, D. Guergour, A. K. Sakhi, A. Sabaredzovic, C. Thomsen, I. Pin, R. Slama, C. Corne, C. Philippat

    Environ. Int. 2023, 173, 107840

  • Article • Intracellular accumulation and immunological response of NIR-II polymeric nanoparticles [Full paper ]

    I. Moskalevska, V. Faure, L. Haye, M. Mercey-Ressejac, A. K. Dey, B. Chovelon, L. K. Soro, L. J. Charbonnière, A. Reisch, A. S. Klymchenko, P. N. Marche, J.-L. Coll, Z. Macek Jilkova, X. Le Guévuel

    Int. J. Pharm. 2023, 630, 122439

  • Article • Detection of Small Molecules by Fluorescence Intensity using Single Dye Labeled Aptamers and Quencher Transition Metal Ions [Full paper ]

    B. Billet, B. Chovelon, E. Fiore, P. Faure, C. Ravelet, E. Peyrin

    Biosens. Bioelectron. 2022, 205, 114091

  • Article • Crystal and molecular structure of V-amylose complexed with butan-1-ol [Full paper ]

    C. A. K. Le, K. Mazeau, Y. Nishiyama, Y. Ogawa, L. Choisnard, D. Wouessidjewe,

    Polymer, 2022, 243, 12451

  • Article • Topological defects in polycrystalline hexosomes from β-cyclodextrin fatty esters [Full paper ]

    Putaux, J. L. Lancelon-Pin, C. Choisnard, L. Gèze, A. Wouessidjewe, D.

    Soft Matter, 2022, 18, 2028-2038

  • Article • COVID-19 mass vaccination - an illustration of the impact of syringe choice on the effectiveness of mass vaccination campaigns [Full paper ]

    Mazet R., Choisnard L., Leenhardt J., Epaulard O., Brudieu E., Bedouch P.

    Emerg Microbes Infect, 2022, 11, 804-806

  • Article • A fragment-based drug discovery strategy applied to the identification of NDM-1 β-lactamase inhibitors [Full paper ]

    Jérémy Caburet, Benjamin Boucherle, Sofiane Bourdillon, Giorgia Simoncelli, Federica Verdirosa, Jean-Denis Docquier, Yohann Moreau, Isabelle Krimm, Serge Crouzy, Marine Peuchmaur

    European Journal of Medicinal Chemistry 240 (2022) 114599

  • Article • A quality by design approach for the qualification of automating compounding device for parenteral nutrition [Full paper ]

    Quentin Perrier, Marie Piquemal, Julien Leenhardt, Luc Choisnard, Roseline Mazet, Marie-Dominique Desruet, Marjorie Durand, Pierrick Bedouch

    European Journal of Pharmaceutical Sciences, 2022,179: 106275

  • Article • Quantification of ions and organic molecules, in nanoliter samples, in the absence of reference materials [Full paper ]

    L. Lavigne, L. Choisnard, E. Peyrin, F. Oukacine

    Anal. Chem. 2022, 94, 15546−15552

  • Article • Helical Inclusion Complexes of Amylose with Aromatic Compounds: Crystallographic Evidence for New V-type Allomorphs [Full paper ]

    Le, C. A. K. Ogawa, Y. Grimaud, F. Nishiyama, Y. Morfin, I. Potocki-Veronese, G. Choisnard, L. Wouessidjewe, D. Putaux, J. L.

    Crystal Growth & Design 2022

  • Article • Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter [Full paper ]

    V. Chaptal, V. Zampieri, Benjamin Wiseman, C. Orelle, Juliette Martin, K.A. Nguyen, A. Gobet, M. Di Cesare, S. Magnard, W. Javed, Jad, Eid, A. Kilburg, M. Peuchmaur, J. Marcoux, M. Monticelli, M. Hogbom, G. Schoehn, J.M. Jault, A.Boumendjel et al

    Sci. Adv., 2022, 8, eabg9215

  • Article • Exploring the Structure-Activity Relationship of Benzylidene-2,3-Dihydro-1H-Inden-1-One Compared to Benzofuran-3(2H)-One Derivatives as Inhibitors of Tau Amyloid Fibers [Full paper ]

    Emeline Boukherrouba, Camille Larosa, Kim-Anh Nguyen, Jérémy Caburet, Laurent Lunven, Hugues Bonnet, Antoine Fortuné, Ahcène Boumendjel, Benjamin Boucherle, Sabine Chierici, Marine Peuchmaur

    Eur. J. Med. Chem. 2022, 231, 114139

  • Article • An Evolutionary Conserved Detoxification System for Membrane Lipid–Derived Peroxyl Radicals in Gram-Negative Bacteria [Full paper ]

    Marwa Naguib, Nicolás Feldman, Paulina Zarodkiewicz, Holly Shropshire, Christina Biamis, Omar M. El-Halfawy, Julia McCain, Clément Dezanet, Jean-Luc Décout, Yin Chen, Gonzalo Cosa, Miguel A. Valvano

    PLOS Biol. 2022, 20, e3001610

  • Article • In Vitro Rescue of the Bile Acid Transport Function of ABCB11 Variants by CFTR Potentiators [Full paper ]

    Elodie Mareux, Martine Lapalus, Amel Ben Saad, Renaud Zelli, Mounia Lakli, Yosra Riahi, Marion Almes, Manon Banet, Isabelle Callebaut, Jean-Luc Decout, Thomas Falguières, Emmanuel Jacquemin, Emmanuel Gonzales

    Int. J. Mol. Sci. 2022, 18, 10758

  • Article • Bioactive Aurones, Indanones, and Other Hemiindigoid Scaffolds: Medicinal Chemistry and Photopharmacology Perspectives [Full paper ]

    Leticia M. Lazinski, Guy Royal, Maxime Robin, Marc Maresca, Romain Haudecoeur

    J. Med. Chem. 2022, 65, 12594 625

  • Article • Enantioselective Approach for Expanding the Three-Dimensional Space of Tetrahydroquinoline to Develop BET Bromodomain Inhibitors [Full paper ]

    Marie-Ange Lespinasse, Kaiyao Wei, Justine Perrin, Matthias Winkler, Sieme Hamaidia, Alexis Leroy, Zuzana Macek Jilkova, Christian Philouze, Patrice N. Marche, Carlo Petosa, Jérôme Govin, Anouk, Emadali, Yung-Sing Wong

    Chem. Eur. J. 2022, 28, e202202293

  • Article • ATP7B-Deficient Hepatocytes Reveal the Importance of Protein Misfolding Induced at Low Copper Concentration [Full paper ]

    P. Charbonnier, B. Chovelon, C. Ravelet, T. D. Ngo, M. Chevallet and A. Deniaud

    Cells, 2022, 11, 3400

  • Article • S.S. Grp, Phenol and Phthalate Effects on Thyroid Hormone Levels during Pregnancy: Relying on In Vitro Assays and Adverse Outcome Pathways to Inform an Epidemiological Analysis [Full paper ]

    D. Nakiwala, P.D. Noyes, P. Faure, B. Chovelon, C. Corne, A.S. Gauchez, D. Guergour, S. Lyon-Caen, A.K. Sakhi, A. Sabaredzovic, C. Thomsen, I. Pin, R. Slama, C. Philippat

    Environ. Health Perspect. 2022, 130, 117004

  • Article • Biodriven investigation of the wild edible mushroom Pleurotus eryngii revealing unique properties as functional food [Full paper ]

    S. Teniou, A. Bensegueni, B.M. Hybertson, B. Gao, S.K. Bose, J.M. McCord, B. Chovelon, C. Bensouici, A. Boumendjel, I. Hininger-Favier

    J. Funct. Foods., 2022, 89, 104965

  • Article • Stability of catecholamines in whole blood: Influence of time between collection and centrifugation [Full paper ]

    Q. Despinasse, L. Choisnard, P. Faure, D. Guicherd, E. Peyrin, C. Ravelet, B. Chovelon

    Clin. Chem. Lab. Med. 2021, 59, e83 85

  • Article • Anti-pesticide DNA aptamers fail to recognize their targets with asserted micromolar dissociation constants [Full paper ]

    L. Zara, S. Achilli, B. Chovelon, E. Fiore, J.J Toulmé, E. Peyrin, C. Ravelet,

    Anal. Chim. Acta 2021, 1159, 338382

  • Article • Does phytochemical diversity of wild plants as Erythrophleum genus correlate with geographical origin? [Full paper ]

    Cédric Delporte *, Nausicaa Noret, Cécile Vanhaverbeke, Olivier J. Hardy, Jean-François Martin, Marie Tremblay-Franco, David Touboul, Anais Gorel, Marie Faes, Caroline Stévigny, Pierre Van Antwerpen, Florence Souard

    Molecules 2021, 26(6), 1668

  • Article • Aptamer Switches Regulated by Post-Transition/Transition Metal Ions [Full paper ]

    B. Billet, B. Chovelon, E. Fiore, F. Oukacine, M-A Petrillo, P. Faure, C. Ravelet, E. Peyrin

    Angew. Chem. Int. Ed. 2021, 60, 12346–12350

  • Article • Optimizing chitin depolymerization by lysozyme to long-chain oligosaccharides [Full paper ]

    A. Masselin, A. Rousseau, S. Pradeau, L. Fort, R. Gueret, L. Buon, S. Armand, S. Cottaz, L. Choisnard, S. Fort

    Mar. Drugs 2021, 19, 320

  • Article • Simultaneous analysis of PAH urinary mono- and dihydroxylated metabolites by GC-MS-MS following SPE and two-stage derivatization [Full paper ]

    M. Marques, A. Maitre, L. Choisnard, C. Demeilliers, R. Persoons

    Anal. Bioanal. Chem. 2021, 413, 6823 6835

  • Article • Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer’s disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference [Full paper ]

    I. Baussanne, O. Firstova, A. Botezatu Dediu, C. Larosa, B. Furdui, I. Ottilia Ghinea, A. Thomas, S. Chierici, R. Dinica, M. Demeunynck

    Bioorg. Chem. 2021, 116, 105390

  • Article • Comparison of three automated compounding devices for parenteral nutrition according to four key technical tests [Full paper ]

    Julien Leenhardt; Marjorie Durand; Luc Choisnard; Marie-Dominique Desruet; Roseline Mazet; Pierrick Bedouch

    European Journal of Hospital Pharmacy, 2021, 0, 1-6

  • Article • Pharmacological Chaperones Improve Intra-Domain Stability and Inter-Domain Assembly via Distinct Binding Sites to Rescue Misfolded CFTR [Full paper ]

    N. Baatallah, A. Elbahnsi, J.-P. Mornon, B. Chevalier, I. Pranke, N. Servel, R. Zelli, J.-L. Decout, A. Edelman, I. Sermet-Gaudelus, I. Cellebaut, A. Hinzpeter

    Cell. Mol. Life Sci. 2021, 78, 7813-7829

  • Article • β-Carboline as a Privileged Scaffold for Multitarget Strategies in Alzheimer’s Disease Therapy [Full paper ]

    A. Beato, A. Gori, B. Boucherle, M. Peuchmaur, R. Haudecoeur

    J. Med. Chem. 2021, 64, 13921422

  • Article • Does the Phytochemical Diversity of Wild Plants Like the Erythrophleum Genus Correlate with Geographical Origin? [Full paper ]

    C. Delporte, N. Noret, C. Vanhaverbeke, O. J. Hardy, J.-F. Martin, M. Tremblay-Franco, D. Touboul, A. Gorel, M. Faes, C. Stévigny, P. Van Antwerpen, F. Souard

    Molecules 2021, 26, 1668

  • Article • Two-Step Immobilization of Metronidazole Prodrug on TEMPO Cellulose Nanofibrils through Thiol-Yne Click Chemistry for in Situ Controlled Release [Full paper ]

    H. Durand, I. Baussanne, M. Demeunynck, J. Viger-Gravel, L. Emsley, M. Bardet, E. Zeno, N. Belgacem, J. Bras

    Carbohydr. Polym. 2021, 262, 117952

  • Article • Development of an Innovative Maceration Technique to Optimize Extraction and Phase Partition of Natural Products [Full paper ]

    A. Gori, B. Boucherle, A. Rey, M. Rome, N. Fuzzati, M. Peuchmaur

    Fitoterapia 2021, 148, 104798

  • Article • Interest of Homodialkyl Neamine Derivatives against Resistant P. Aeruginosa, E. Coli, and β-Lactamases-Producing Bacteria—Effect of Alkyl Chain Length on the Interaction with LPS [Full paper ]

    J. Swain, C. Dezanet, H. Chalhoub, M. Auquière, J. Kempf, J.-L. Décout, M.-P. Mingeot-Leclercq

    Int. J. Mol. Sci. 2021, 22, 8707

  • Article • Untargeted Metabolomics Approach to Discriminate Mistletoe Commercial Products [Full paper ]

    C. Vanhaverbeke, D. Touboul, N. Elie, M. Prévost, C. Meunier, S. Michelland, V. Cunin, et al

    Sci. Rep. 2021, 11, 14205

  • Article • Crossing of the Cystic Barriers of Toxoplasma Gondii by the Fluorescent Coumarin Tetra-Cyclopeptide [Full paper ]

    Dard, Céline, Baptiste Leforestier, Flaviane Francisco Hilário, Mohamed Dit Mady Traoré, Marie-Ange Lespinasse, Basile Pérès, Marie-Carmen Molina, et al

    Molecules 26, no 24 (janvier 2021): 7506

  • Article • Ditopic Chelators of Dicopper Centers for Enhanced Tyrosinases Inhibition [Full paper ]

    E. Buitrago, C. Faure, L. Challali, E. Bergantino, A. Boumendjel, L. Bubacco, M. Carotti, R. Hardré, M. Maresca, C. Philouze, H. Jamet, M. Réglier, C. Belle

    Chem. Eur. J. 2021, 27, 43844393

  • Article • Pyrrolizidine-Derived Alkaloids: Highly Toxic Components in the Seeds of Crotalaria Cleomifolia Used in Popular Beverages in Madagascar [Full paper ]

    A. H. D. Solofomalala, C. F. Rajemiarimoelisoa, R. L. Judicael, H. R. Randrianarivo, D. A. D. Rakoto, V. L. Jeannoda, A. Boumendjel

    Molecules 2021, 26, 3464

  • Article • Preclinical Evaluation of Sodium Selenite in Mice: Toxicological and Tumor Regression Studies after Striatum Implantation of Human Glioblastoma Stem Cells [Full paper ]

    L. Larrouquère; S. Berthier; B. Chovelon; C. Garrel; V. Vacchina; H. Paucot; J. Boutonnat; P. Faure; F. Hazane-Puch

    Int. J. Mol. Sci. 2021, 22, 10646

  • Article • Polymorphism of V-Amylose Cocrystallized with Aliphatic Diols [Full paper ]

    C. Anh Khanh Le, L. Choisnard, D. Wouessidjewe, J.-L. Putaux

    Polymer 2021, 213, 123302

  • Article • Crystal and Molecular Structure of V-Amylose Complexed with Ibuprofen [Full paper ]

    C. Anh Khanh Le, Y. Ogawa, F. Dubreuil, F. Grimaud, K. Mazeau, G. R. Ziegler, S. Tanwar, Y. Nishiyama, G. Potocki-Veronese, L. Choisnard, D. Wouessidjewe, J.-L. Putaux

    Carbohydr. Polym. 2021, 261, 117885

  • Article • Melting Curve Analysis of Aptachains: Adenosine Detection with Internal Calibration [Full paper ]

    C. Lu, C. Saint-Pierre, D. Gasparutto, Y. Roupioz, C. Ravelet, E. Peyrin, A. Buhot

    Biosensors 2021, 11, 112

  • Article • A Cobalt Oxide–Polypyrrole Nanocomposite as an Efficient and Stable Electrode Material for Electrocatalytic Water Oxidation [Full paper ]

    D. V. Morales, C. N. Astudillo, V. Anastasoaie, B. Dautreppe, B. F. Urbano, B. L. Rivas, C. Gondran, D. Aldakov, B. Chovelon, D. André, J.-L. Putaux, C. Lancelon-Pin, S. Sirach, E.-M. Ungureanu, C. Costentin, M.-N. Collomb, J. Fortage

    Sustainable Energy Fuels 2021, 5, 4710 4723

  • Article • Theranostic AGuIX Nanoparticles as Radiosensitizer: A Phase I, Dose-Escalation Study in Patients with Multiple Brain Metastases (NANO-RAD Trial) 

    C. Verry, S. Dufort, J. Villa, M. Gavard, C. Iriart, S. Grand, J. Charles, B. Chovelon, J.-L. Cracowski, J.-L. Quesada, C. Mendoza, L. Sancey, A. Lehmann, F. Jover, J.-Y. Giraud, F. Lux, Y. Crémillieux, S. McMahon, P. J. Pauwels et al

    Radiother. Oncol. 2021, 160, 159 165

  • Article • Nanoscale Dynamics of Peptidoglycan Assembly during the Cell Cycle of Streptococcus Pneumoniae  [Full paper ]

    J. Trouvé, A. Zapun, C. Arthaud, C. Durmort, A.-M. Di Guilmi, B. Söderström, A. Pelletier, C. Grangeasse, D. Bourgeois, Y.-S. Wong, C. Morlot

    Curr. Biol. 2021, 31, 2844-2856.e6

  • Article • Crossing of the Cystic Barriers of Toxoplasma Gondii by the Fluorescent Coumarin Tetra-Cyclopeptide [Full paper ]

    C. Dard, B. Leforestier, F. Francisco Hilário, M. Dit Mady Traoré, M.-A. Lespinasse, B. Pérès, M.-C. Molina, R. Pereira de Freitas, A. Milet, D. Maubon, Y.-S. Wong

    Molecules 2021, 26, 7506

  • Patent • Method for synthesizing diversely substituted purines 

    Jean-Luc Decout, Renaud Zelli, Wael Zeinyeh, Benjamin Boucherle, Romain Haudecoeur

    2021 • 

  • Article • Enantiomeric sensing and separation by nucleic acids [Full paper ]

    F. Oukacine, C. Ravelet, E. Peyrin

    Trends Anal. Chem. 2020, 122, 115733

  • Article • Pharmacokinetic study of intravenously administered artemisinin-loaded surface-decorated amphiphilic γ-cyclodextrin nanoparticles [Full paper ]

    J. Boumbéwendin Gérard Yaméogo, R. Mazet, D. Wouessidjewe, L. Choisnard, D. Godin-Ribuot, J.-L. Putaux, R. Semdé, A. Gèze

    Mat. Sci. Engin. C 2020, 106, 110281

  • Article • Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity [Full paper ]

    L. Froux, A. Elbahnsi, B. Boucherle, A. Billet, N. Baatallah, B. Hoffmann, J. Alliot, R. Zelli, W. Zeinyeh, R. Haudecoeur, A. Fortuné, S. Mirval, C. Simard, P. Lehn, J.-P. Mornon, I. Callebaut, J.-L. Décout

    Eur. J. Med. Chem. 2020, 190, 112116

  • Article • High-Resolution Shortwave Infrared Imaging of Vascular Disorders Using Gold Nanoclusters. 

    Yu Z, Musnier B, Wegner KD, Henry M, Chovelon B, Desroches-Castan A, Fertin A, Resch-Genger U, Bailly S, Coll JL, Usson Y, Josserand V, Le Guével X.

    ACS Nano, 2020, 14, 4973-4981

  • Article • Surface functionalization of gold nanoclusters with arginine: a trade-off between microtumor uptake and radiotherapy enhancement. 

    M. Broekgaarden, A. L. Bulin, E. Porret, B. Musnier, B. Chovelon, C. Ravelet, L. Sancey, H. Elleaume, P. Hainaut, J. L. Coll, X. Le Guével

    Nanoscale 2020, 12, 6959-6963

  • Article • Influence of delayed separation of plasma from whole blood & centrifugation protocol on Zn plasma concentration [Full paper ]

    M. Leger, Q. Despinasse, P. Faure, J. Arnaud, C. Ravelet, B. Chovelon

    Clin Chem Lab Med e279-e281

  • Article • Phytochemical and Biological Investigation of Helianthemum nummularium, a High-Altitude Growing Alpine Plant Overrepresented in Ungulates Diets [Full paper ]

    M Agostini, I Hininger-Favier‡, L Marcourt‡, B Boucherle‡, B Gao, B M Hybertson, S K Bose, J M McCord, A Millery, M Rome, E Ferreira Queiroz, J-L Wolfender , C Gallet, A Boumendjel

    Planta Medica, 2020, 86, 1185-1190

  • Article • Advances in the Design of Genuine Human Tyrosinase Inhibitors for Targeting Melanogenesis and Related Pigmentations [Full paper ]

    Brayan Roulier, Basile Pérès, Romain Haudecoeur

    J. Med. Chem. 2020, 63, 22, 13428–13443

  • Article • Chromones bearing amino acid residues: Easily accessible and potent inhibitors of the breast cancer resistance protein ABCG2 [Full paper ]

    E. Roussel, A. Moréno, N. Altounian, C. Philouze, B. Pérès, A. Thomas, O. Renaudet, P. Falson, A. Boumendjel

    Eur. J. Med. Chem. 2020, 202, 112503

  • Article • The surface chemistry of a nanocellulose drug carrier unravelled by MAS−DNP [Full paper ]

    A. Kumar, H. Durand, E. Zeno, C. Balsollier, B. Watbled, C. Sillard, S. Fort, I. Baussanne, N. Belgacem, D. Lee, S. Hediger, M. Demeunynck, J. Bras, G. De Paëpe.

    Chem. Sci., 2020, 11, 3868-3877

  • Article • Biopharmaceutical Assessment of Dexamethasone Acetate-Based Hydrogels Combining Hydroxypropyl Cyclodextrins and Polysaccharides for Ocular Delivery [Full paper ]

    azet, R. Garcia-Otero, X. Choisnard, L. Wouessidjewe, D. Verdoot, V. Bossard, F. Diaz-Tome, V. Blanc-Marquis, V. Otero-Espinar, F. J. Fernandez-Ferreiro, A. Geze, A.

    Pharmaceutics 2020, 12 (8), 717

  • Article • Recent Advances in the Design of Topical Ophthalmic Delivery Systems in the Treatment of Ocular Surface Inflammation and Their Biopharmaceutical Evaluation 

    Mazet, R. Yameogo, J. B. G. Wouessidjewe, D. Choisnard, L. Geze, A.

    Pharmaceutics, 2020, 12 (6), 570

  • Article • Aurone derivatives as promising antibacterial agents against resistant Gram-positive pathogens [Full paper ]

    H. Olleik, S. Yahiaoui, B. Roulier, E. Courvoisier-Dezord, J. Perrier, B. Pérès, A. Hijazi, E. Baydoun, J. Raymond, A. Boumendjel, M. Maresca, R. Haudecoeur

    Eur. J. Med. Chem. 2019, 165, 133–141

  • Article • A short chemically modified dsRNA-binding PNA (dbPNA) inhibits influenza viral replication by targeting viral RNA panhandle structure [Full paper ]

    J. Kesy, K. M. Patil, S. R. Kumar, Z. Shu, H. Y. Yong, L. Zimmermann, A. A. Lerk Ong, D.-F. Kaixin Toh, M. S. Krishna, L. Yang, J.-L. Decout, D. Luo, M. Prabakaran, G. Chen, E. Kierzek

    Bioconjugate Chem. 2019, 30, 931–943

  • Article • Capillary electrophoretic apparatus for the endpoint detection in microtitration methods [Full paper ]

    F. Oukacine, L. Choisnard, A. Gèze, E. Peyrin

    J. Chromatogr. A, 2019

  • Article • Could we expect new praziquantel derivatives? A meta pharmacometrics/pharmacoinformatics analysis of all antischistosomal praziquantel derivatives found in the literature [Full paper ]

    V.B. Ribeiro da Silva, B. Boucherle, J. El-Methni, B. Hoffmann, A.L. da Silva, A. Fortune, M. do Carmo Alves de Lima, A. Thomas

    SAR AND QSAR IN ENVIRONMENTAL RESEARCH 2019, VOL. 30, NO. 6, 383–401

  • Article • Tuning the electron storage potential of a charge-photoaccumulating Ru(II) complex by a DFT-guided approach 

    N. M. Randell, J. Rendon, M. Demeunynck, P.-A. Bayle, S. Gambarelli, V. Artero, J.-M. Mouesca, M. Chavarot-Kerlidou

    Chem. Eur. J., 2019, 25, 13911-13920

  • Article • Optimization of the Chromone Scaffold through QSAR and Docking Studies: Identification of Potent Inhibitors of ABCG2 [Full paper ]

    E. Roussel, V.-K. Tran-Nguyen, K. Bouhedjar, M.-A. Dems, A. Belaidi, B. Matougui, B. Peres, A. Azioune, O. Renaudet, P. Falson and A. Boumendjel

    Eur. J. Med. Chem. 2019, 184, 111772

  • Article • Chimeric Protein-Protein Interface Inhibitors Allow Efficient Inhibition of Type III Secretion Machinery and Pseudomonas aeruginosa Virulence [Full paper ]

    Ngo, T.-D.; Plé, S.; Thomas, A.; Barette, C.; Fortuné, A.; Bouzidi, Y.; Fauvarque, M.-O.; Pereira de Freitas, R.; Francisco Hilário, F.; Attrée, I.; Wong, Y.-S.; Fraudry, E.

    ACS Infect. Dis.

  • Article • Single Crystals of V-Amylose Complexed with Bicyclic Organic Compounds. Special Issue: Polymer‐Solvent Complexes and Intercalates  [Full paper ]

    Cong‐Anh‐Khanh Le Luc Choisnard Denis Wouessidjewe Jean‐Luc Putaux

    MACROMOLECULAR SYMPOSIA

  • Article • Cell morphology and nucleoid dynamics in dividing Deinococcus radiodurans 

    K. Floc'h, F. Lacroix, P. Servant, Y.-S. Wong, J.-P. Kleman, D. Bourgeois, J. Timmins

    Nat. Commun 2019, 10, 3815

  • Patent • Inhibiteurs selectifs du transporteur bcrp/abcg2 utilises comme agents pour abolir la résistance aux anticancéreux 

    A. Boumendjel, P. Falson, A. Moreno, B. Peres, E. Roussel

    2019 • 

  • Patent • Compounds for treating cystic fibrosis 

    Isabelle Callebaut, Jean-paul Mornon, Jean-Luc Decout, Frederic Becq, Pierre Lehn, Brice Hoffman, Benjamin Boucherle, Romain Haudecoeur, Antoine Fortune, Clement Boinot, Julien Alliot

    2019 • 

  • Article • Make Azoles Active Again: Chalcones as Potent Reversal Agents of Transporters-Mediated Resistance in Candida albicans. 

    S. Nim, P. Baghel, V.-K. Tran-Nguyen, B. Peres, K.-A. Nguyen, A. Di Pietro, P. Falson, R. Prasad, A. Boumendjel

    Future Med. Chem. 2018, 10, 2177-2186.

  • Article • High-content imaging assay to evaluate toxoplasma gondii invasion and proliferation: a multiparametric assay to screen new compounds 

    B. Touquet, L. Pellissier, P. Cavailles, W. Yi, V. Bellini, C. Mercier, M.-F. Delauw, A. Boumendjel, D. Aldebert.

    PlosOne, 2018, accepté

  • Article • Non-SELEX Isolation of DNA Aptamers for the Homogeneous-Phase Fluorescence Anisotropy Sensing of Tau Proteins [Full paper ]

    S. Lisi, E. Fiore, S. Scarano, E. Pascale, Y. Boehmann, F. Ducongé, S. Chierici, M. Minnuni, E. Peyrin, C. Ravelet

    Anal. Chim. Acta 2018, 1038, 173-181

  • Article • Enzymatically Activated Glyco-Prodrugs of Doxorubicin Synthesized by a Catalysis-Free Diels−Alder Reaction [Full paper ]

    D. Bliman, M. Demeunynck, P. Leblond, S. Meignan, I. Baussane, S. Fort

    Bioconjugate Chem. 2018, 29, 2370−2381

  • Article • A ππ* State Enables Photoaccumulation of Charges on a π‐Extended Dipyridophenazine Ligand in a Ru(II) Polypyridine Complex [Full paper ]

    J. Schindler, Y. Zhang, P. Traber, J. F. Lefebvre, S. Kupfer, M. Demeunynck, S. Gräfe, M. Chavarot-Kerlidou, B. Dietzek

    J. Phys. Chem. C 2018, 122, 83−95

  • Article • Photophysics of a Ruthenium Complex with a π-Extended Dipyridophenazine Ligand for DNA Quadruplex Labeling [Full paper ]

    J. Schindler, P. Traber, L. Zedler, Y. Zhang, J.F. Lefebvre, S. Kupfer, S. Gräfe, M. Demeunynck, M. Chavarot-Kerlidou, B. Dietzek

    J. Phys. Chem. A, 2018,122, 6558-69

  • Article • Nascent teichoic acids insertion into the cell wall directs the localization and activity of the major pneumococcal autolysin LytA 

    J. Bonnet, C. Durmort, I. Mortier-Barrière, N. Campo, M. Jacq, C. Moriscot, D. Straume, K. H. Berg, L. Håvarstein, Y.-S. Wong, T. Vernet, A.-M. Di Guilmi

    Cell Surf. 2018, 2, 24-37

  • Article • One-Pot two step metabolic labelling of teichoic acid and direct labelling of peptidoglycan reveals tight coordination of both polymers inserted into pneumococcus cell wall 

    J. Bonnet, Y.-S. Wong, T. Vernet, A.-M. Di Guilmi, A. Zapun, C. Durmort

    ACS Chem. Biol. 2018, 13, 2010-2015

  • Article • Combining theoretical and experimental data to decipher CFTR 3D structures and functions 

    B. Hoffmann, A. Elbahnsi, P. Lehn, J.-L. Décout, F. Pietrucci, J.-P. Mornon, I. Callebaut

    Cell. Mol. Life Sci. 2018, in press.

  • Article • Effect of cardiolipin on the antimicrobial activity of a new amphiphilic aminoglycoside derivative on Pseudomonas aeruginosa 

    J. Swain, M. El Khoury, J. Kempf, F. Briée, P. Van Der Smissen, J.-L. Décout, M.-P. Mingeot-Leclercq

    PLoS One 2018, 13, e0201752

  • Article • Broad-spectrum antibacterial amphiphilic aminoglycosides: A new focus on the structure of the lipophilic groups extends the series of active dialkyl neamines 

    L. Zimmermann, J. Kempf, F. Briée, J. Swain, M.-P. Mingeot-Leclercq, J.-L. Décout

    Eur. J. Med. Chem. 2018, in press.

  • Article • Piperidinyl-Embeded Chalcones Possessing anti PI3Kδ Inhibitory Properties Exhibit Anti-atopic Properties in Preclinical Models 

    C. Dumontet, G.Beck, F. Gardebien, R. Haudecoeur, D. Mathé, E.-L. Matera, A. Tourette, E. Mattei, J. Esmenjaud, C. Boyere, A. Nurisso, M. Peuchmaur, B. Peres, G. Bouchaud, A. Magnan, G. Monneret and A. Boumendjeld

    Eur. J. Med. Chem. 2018, In Press

  • Article • Polymorphism of crystalline complexes of V-amylose with fatty acids [Full paper ]

    Cong-Anh-Khanh Le, Luc Choisnard, Denis Wouessidjewe, Jean-Luc Putaux

    International Journal of Biological Macromolecules 2018,119, 555-564

  • Article • The water test could be a good indication to evaluate the effectiveness of the sterile barrier system of rigid sterilization containers. [Full paper ]

    L. Decarout, C. Lambert, L. Choisnard, C. Andonian, C. Fayard

    Annales Pharmaceutiques Françaises, 2018, 76(6), 464-472

  • Article • The advantages and challenges raised by the chemisty of aldehydic cellulose nanofibers in medicinal chemistry [Full paper ]

    I. Baussanne, J. Bras, B. Watbled, M. Demeunynck

    Future Med. Chem. 2018, 2679-2683

  • Article • Investigation of Combined Cyclodextrin and Hydrogel Formulation for Ocular Delivery of Dexamethasone Acetate by Means of Experimental Designs 

    Roseline Mazet , Luc Choisnard , Delphine Levilly , Denis Wouessidjewe and Annabelle Gèze

    Pharmaceutics, 2018 , 10 , 249

  • Article • Mirror-Image Aptamer Kissing Complex for Arginine-Vasopressin Sensing [Full paper ]

    B. Chovelon, E. Fiore, P. Faure, E. Peyrin, C. Ravelet

    Anal. Chim. Acta, 2018, 1001, 143-150

  • Article • Design, Synthesis and Biological Evaluation of Novel Ring-Opened Cromakalim Analogues with Relaxant Effects on Vascular and Respiratory Smooth Muscles and as Stimulators of Elastin Synthesis 

    M. BOUHEDJA, B. PERES, W. FHAYLI, Z. GHANDOUR, A. BOUMENDJEL, G. FAURY, S. KHELILI

    Eur. J. Med. Chem. 2018, 144, 774-796.

  • Article • Biodistribution and preliminary toxicity studies of nanoparticles made of Biotransesterified β–cyclodextrins and PEGylated phospholipids [Full paper ]

    P. Perret, S. Bacot, A. Gèze, A. Gentil Dit Maurin, M. Debiossat, A. Soubies, V. Blanc-Marquis, L. Choisnard, J. Boutonnat, C. Ghezzi, J.L. Putaux, C. Lancelon-Pin, L.M. Riou,⁎, D. Wouessidjewe

    Materials Science & Engineering C 2018, 85, 7-17

  • Article • Urinary trans-anti-7,8,9,10-tetrahydroxy-7,8,9,10-tetrahydrobenzo(a) pyrene as the most relevant biomarker for assessing carcinogenic polycyclic aromatic hydrocarbons exposure [Full paper ]

    Damien Barbeau, Simon Lutier, Luc Choisnard, Marie Marques, Renaud Persoons, Anne Maitre

    Environment International, 2018, 112, 147–155

  • Article • Inline coupling of electrokinetic preconcentration method to Taylor dispersion analysis for size-based characterization of low-UV-absorbing nanoparticles [Full paper ]

    F. Oukacine, A. Gèze, L. Choisnard, JL. Putaux, JP. Stahl, E. Peyrin

    Anal. Chem. 2018, 90, 2493–2500

  • Article • Glycosyl-Substituted Dicarboxylates as Detergents for the Extraction, Overstabilization, and Crystallization of Membrane Proteins [Full paper ]

    K.-A. Nguyen, M. Peuchmaur, S. Magnard, R. Haudecoeur, C. Boyère, S. Mounien, I. Benammar, V. Zampieri, S. Igonet, V. Chaptal, A. Jawhari, A. Boumendjel, P. Falson

    Angew. Chem. Int. Ed. Engl. 2018, 57, 2948-2952.

  • Article • Identification of coffee leaves using FT-NIR spectroscopy and SIMCA 

    C. Mees, F. Souard, C. Delporte, E. Deconinck, P. Stoffelen, C. Stévigny, J.M. Kauffmann, K. De Braekeleer

    Talanta, 2018, 177, 4–11

  • Article • Metabolomics fingerprint of coffee species determined by untargeted- profiling study using LC-HRMS [Full paper ]

    F. Souard, C. Delporte, P. Stoffelen, E. A. Thévenot, N. Noret, B. Dauvergne, J. M. Kauffmann, Pi. Van Antwerpen, C. Stévigny

    Food Chemistry 245 (2018) 603–612

  • Article • Contrasting cadmium resistance strategies in two metallicolous populations of Arabidopsis halleri 

    M. Corso, M.S. Schvartzman, F. Guzzo, F. Souard, E. Malkowski, M. Hanikenne, N. Verbruggen

    New Phytol. 2018, sous presse

  • Article • Traditional uses, phytochemistry and pharmacological properties of African Nauclea species: A review [Full paper ]

    R. Haudecoeur, M. Peuchmaur, B. Pérès, M. Rome, G. Sotoing Taiwe, A. Boumendjel, B. Boucherle

    Journal of Ethnopharmacology, 2018, 212, 106-136

  • Article • Panoply of Fluorescence Polarization/Anisotropy Signaling Mechanisms for Functional Nucleic Acid-Based Sensing Platforms [Full paper ]

    S. Perrier, V. Guieu, B. Chovelon, C. Ravelet, E. Peyrin

    Anal. Chem. 2018, 90, 4236–4248.

  • Article • Ovarian cancer cells cisplatin sensitization agents selected by mass cytometry target ABCC2 inhibition [Full paper ]

    E. Comsa, K.-A. Nguyen, F. Loghin, A. Boumendjel, M. Peuchmaur, T. Andrieu, P. Falson.

    Future Med. Chem. 2018, 10, 11, 1349-1360

  • Article • An artificial photosynthetic system for photoaccumulation of two electrons on a fused dipyridophenazine (dppz) – pyridoquinolinone ligand [Full paper ]

    Jean-François Lefebvre, Julian Schindler, Philipp Traber, Ying Zhang, Stephan Kupfer, Stefanie Grafe, Isabelle Baussanne, Martine Demeunynck, Jean-Marie Mouesca, Serge Gambarelli, Vincent Artero, Benjamin Dietzek, Murielle Chavarot-Kerlidou

    Chem. Sci., 2018, 9, 4152-4159

  • Oral Comm • Le nettoyeur à vapeur a-t-il une place dans la prise en charge des dispositifs médicaux réutilisables à corps creux en stérilisation? 

    A. Bros, R. Mazet, L. Choisnard, N. Sylvoz, P. Bedouch, C. Guimier-Pingault

  • Article • Toward sensitive immuno-based detection of Tau protein by surface plasmon resonance coupled to carbon nanostructures as signal amplifiers [Full paper ]

    S. Lisi, S. Scarano, S. Fedeli, E. Pascale, S. Cicchi, C. Ravelet, E. Peyrin, M. Minunni

    Biosens. Bioelectron. 2017, 93, 289-292.

  • Article • MRP1-dependent collateral sensitivity via cellular GSH depletion: identifying selective modulators and investigating their interest in MRP1-overexpressing multidrug-resistant cancer cells by comparison with other modulators. [Full paper ]

    D. Lorendeau, L. Dury, R. Nasr, A. Boumendjel, E. Teodori, M. Gütschow, P. Falson, A. Di Pietro, H. Cortay

    Curr. Med. Chem. 2017, 24, 1186-1213.

  • Article • A Lifetime-Sensitive Fluorescence Anisotropy Probe for DNA-based Bioassays: the Case of SYBR Green [Full paper ]

    B. Chovelon, E. Fiore, P. Faure, E. Peyrin, C. Ravelet

    Biosens. Bioelectron. 2017, 90, 140-145.

  • Article • 2-Hydroxypyridine-N-oxide-Embedded Aurones as Potent Human Tyrosinase Inhibitors [Full paper ]

    R. Haudecoeur, M. Carotti, A. Gouron, M. Maresca, E. Buitrago, R. Hardré, E. Bergantino, H. Jamet, C. Belle, M. Réglier, L. Bubacco, A. Boumendjel

    ACS Med. Chem. Lett. 2017, 8, 55-60.

  • Article • Metrics of rhamnogalacturonan-I with β-(1→ 4)-linked galactan side chains and structural basis for its self-aggregation 

    ON Makshakova, TA Gorshkova, PV Mikshina, YF Zuev, S Perez

    Carbohydrate Polymers 2017, (20) 93-101

  • Article • Development of Carbohydrate Nomenclature and Representation 

    S Perez, KF Aoki-Kinoshita

    A Practical Guide to Using Glycomics Databases, 7-25

  • Article • Glyco3D: A Suite of Interlinked Databases of 3D Structures of Complex Carbohydrates, Lectins, Antibodies, and Glycosyltransferases 

    S Pérez, A Sarkar, A Rivet, S Drouillard, C Breton, A Imberty

    A Practical Guide to Using Glycomics Databases, 133-161

  • Article • Colorimetric nanosensor based on a selective target-responsive aptamer kissing complex [Full paper ]

    E. Goux, E. Dausse, V. Guieu, L. Azéma, G. Durand, M. Henry, L. Choisnard, J-J. Toulmé, C. Ravelet, E. Peyrin

    Nanoscale, 2017, 9, 4048 - 4052.

  • Article • Sequence Requirements of Oligonucleotide Chiral Selectors for the Capillary Electrophoresis Resolution of Low-Affinity DNA Binders [Full paper ]

    L . Tohala, F. Oukacine, C. Ravelet, E. Peyrin

    Electrophoresis, 2017, 38, 1383-1390

  • Article • Synthesis of an uncharged tetra-cyclopeptide acting as a transmembrane carrier: Enhanced cellular and nuclear uptake 

    Francisco Hilario, Flaviane Traore, Mohamed Dit Mady Zwick, Vincent Berry, Laurence Simoes-Pires, Claudia A. Cuendet, Muriel Fantozzi, Nicolas Pereira de Freitas, Rossimiriam Maynadier, Marjorie Wein, Sharon Vial, Henri Wong, Yung-Sing

    Org. Lett. 2017, 19, 612-615

  • Article • C1 Metabolism Inhibition and Nitrogen Deprivation Trigger Triacylglycerol Accumulation in Arabidopsis thaliana Cell Cultures and Highlight a Role of NPC in Phosphatidylcholine-to-Triacylglycerol Pathway [Full paper ]

    Meï,Coline E. Cussac,Mathilde Haslam,Richard P. Beaudoin,Frédéric Wong,Yung-Sing Maréchal,Eric Rébeillé,Fabrice

    Front. Plant Sci. 2017, 7

  • Article • Ferrocene-embedded flavonoids targeting the Achilles heel of multidrug-resistant cancer cells through collateral sensitivity. [Full paper ]

    Pérès B, Nasr R, Zarioh M, Lecerf-Schmidt F, Di Pietro A, Baubichon-Cortay H, Boumendjel A

    Eur J Med Chem. 2017, 130, 346-353

  • Article • Self-assembly of amphiphilic biotransesterified B-cyclodextrins : supramolecular structure of nanoparticles and surface properties [Full paper ]

    Jean-Luc Putaux, Christine Lancelon-Pin, François-Xavier Legrand, Marion Pastrello, Luc Choisnard, Annabelle Gèze, Cyrille Rochas and Denis Wouessidjewe

    Langmuir 2017, 33, 7917–7928

  • Article • Selective Luminescent Labeling of DNA and RNA Quadruplexes by p-Extended Ruthenium Light-Up Probes [Full paper ]

    D. Saadallah, M. Bellakhal, S. Amor, J.-F. Lefebvre, M. Chavarot-Kerlidou, I. Baussanne, C. Moucheron, M. Demeunynck, D. Monchaud

    Chem. Eur. J. 2017, 23, 4967–4972

  • Article • Modulators of the Efflux Pump Cdr1p of Candida albicans: Mechanisms of Action and Chemical Features. [Full paper ]

    V. K. Tran-Nguyen, R. Prasad, P. Falson, A. Boumendjel

    Curr. Med. Chem. 2017, 24, 3242-3253.

  • Article • Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides [Full paper ]

    T. Abd El Aziz, C. Ravelet, J. Molgo, E. Fiore, S. Pale, M. Amar, S. Al Khoury, J. Dejeu, M. Fadl, M. Ronjat, G. Sotoing Taiwe, D. Servent, E. Peyrin, M. De Waard

    Sci. Rep., 2017, 7, 7202

  • Article • Occurrences, biosynthesis and properties of aurones as high-end evolutionary products. [Full paper ]

    B. Boucherle, M. Peuchmaur, A. Boumendjel, R. Haudecoeur.

    Phytochemistry, 2017, 142, 92-111.

  • Article • New nanoparticles obtained by co-​assembly of amphiphilic cyclodextrins and nonlamellar single-​chain lipids: Preparation and characterization [Full paper ]

    Nguyen, C-H ; Putaux, J-L; Santoni, G; Tfaili, S; Fourmentin, S; Coty, J-B; Choisnard, L; Geze, A; Wouessidjewe, D; Barratt, G; Lesieur, S; Legrand, F-X

    Int. J. Pharm. 2017, 531(2), 444-456

  • Article • Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia 

    Ersayin A., Thomas A., Seyve L., Thielens N., Castellan M., Marlu R., Polack B., Dagher M-C.

    Haematologica 2017, 102, e483

  • Article • Linear chain formation of split-aptamer dimers on surfaces triggered by adenosine [Full paper ]

    L. Chenze, C. Saint-Pierre, D. Gasparutto, Y. Roupioz, E. Peyrin, A. Buhot.

    Langmuir, 2017, 33, 12785–12792

  • Article • Indolizine-based scaffolds as efficient and versatile scaffolds for drug target identification – Synthesis and study of biotin-tagged anti-angiogenic drugs 

    Marie Arvin-Berod, Simon Bonte, Agnès Desroches-Castan, Sabine Brugière, Yohann Couté, Laurent Guyon, Jean-Jacques Feige, Isabelle Baussanne and Martine Demeunynck

    ACS Omega, 2017, 2, 9221-9230

  • Article • Hydroxyl ketone−based HDAC inhibitors to gain insights into class I histone deacetylase (HDAC) selectivity versus HDAC6 

    M. D. M. Traoré, V. Zwick, C. A. Simoes−Pires, A. Nurisso, M. Issa, M. Cuendet, M. Maynadier, S. Wein, H. Vial, H. Jamet, Y.−S. Wong

    ACS Omega 2017, 2, 1550−1562

  • Article • Specific and spatial labeling of choline−containing teichoic acids in Streptococcus pneumoniae by click chemistry 

    A.−M. Di Guilmi, J. Bonnet, S. Peissert, C. Durmort, B. Gallet, T. Vernet, N. Gisch, Y.−S. Wong

    Chem. Commun. 2017, 53, 10572−10575

  • Article • Terpenoids from Platostoma rotundifolium (Briq.) A. J. Paton Alter the Expression of Quorum Sensing-Related Virulence Factors and the Formation of Biofilm in Pseudomonas aeruginosa PAO1 [Full paper ]

    T. Rasamiravaka, J. Ngezahayo, L. Pottier, S. Ribeiro, F. Souard, L. Hari, C. Stévigny, ME. Jaziri, P. Duez

    Int J Mol Sci. 2017; 18(6): 1270.

  • Article • Responses of above- and belowground fungal symbionts to cessation of mowing in subalpine grassland ecosystem 

    M.N. Binet, D. Van Tuinen, F. Souard, D. van Tuinen, L. Sage, S. Perigon, C. Gallet, D. Redecker, N. Legay, S. Lavorel, B. Mouhamadou

    Fungal Ecology, 2017, 25, 14-21

  • Article • A One-Pot Synthesis of Highly Functionalized Purines [Full paper ]

    R. Zelli, W. Zeinyeh, R. Haudecoeur, J. Alliot, B. Boucherle, I. Callebaut, J.-L. Decout

    Org. Lett. 19, 2017, 23, 6360-6363

  • Patent • Leurre GD-FXa mutant  

    Dagher, M. C., Thomas, A., Marlu, R., Ersayin, A., Polack, B.

    2017 • 

  • Patent • Clamps moléculaires d’extraction et stabilisation en solution des protéines membranaires. 

    K. A. Nguyen, S. Magnard, M. Peuchmaur, J. Dauvergne, A. Boumendjel, P. Falson

    2017 • 

  • Patent • Metabolic labeling of bacterial teichoic acids cell wall 

    T. Vernet, Y.-S. Wong, A.-M. Di Guilmi

    2017 • CEA/CNRS

  • Book • Nephrotoxicity of Natural Products: Aristolochic Acid and Fungal Toxins 

    Comprehensive Toxicology (Third Edition)

    V. Bunel, F. Souard, M-H Antoine, C. Stevigny J.L. Nortier

    2017 • 340-379,

  • Oral Comm • Dynamics of fucose and LewisX in lectin-binding sites 

    S Pérez, A Sarkar, A Rivet, S Drouillard, C Breton, A Imberty

  • Oral Comm • Popular Glycociences 

    Serge Perez

  • Article • Fluorescence Anisotropy-Based Structure-Switching Aptamer Assay Using a Peptide Nucleic Acid (PNA) Probe [Full paper ]

    E. Goux, Q. Lespinasse, V. Guieu, S. Perrier, C. Ravelet, E. Fiore, E. Peyrin

    Methods, 2016, 97, 69–74

  • Article • Human Tyrosinase and related proteins, are they new targets to fight melanoma? 

    E. Buitrago, R. Hardre, R. Haudecoeur, H. Jamet, C. Belle, A. Boumedjel, M. Reglier

    Curr. Top. Med. Chem. 2016, 3033-3047.

  • Article • Structural insights and membrane binding properties of MGD1, the major galactolipid synthase in plants.  

    Rocha J., Sarkis J., Thomas A., Pitou L., Radzimanowski J., Audry M., Chazalet V., de Sanctis D., Palcic M., Block M., Girard-Egrot A., Maréchal E., Breton C.

    The Plant Journal, 85(5), 622-33

  • Article • Les biomolécules en biotechnologies 

    J.L. LENORMAND, C. DUMORT, W. RACHIDI, S. BOURGOIN, Ph. BULET, M. DE WAARD, S. PEREZ & B. PRIEM E. DROUET, R. SODOYER, J. BRETON, D. GASPARUTTO & M. SEVE

    Introduction aux biotechnologies en santé, Tome 1, S. Bourgoin-Voillard, W. Rachidi & M. Seve, Eds., Lavoisier, Tec & Doc

  • Article • Chemical composition of the pods of Albizia polyphylla [Full paper ]

    Rajemiarimoelisoa C. F., Boyère C., Pellissier L., Peuchmaur M., Randrianarivo H. R., Doll Rakoto D. A., Jeannoda V. L., Boumendjel A.

    Nat. Prod. Res. 2016, 30, 1557-1560.

  • Article • ELAKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform [Full paper ]

    B. Chovelon, G. Durand, E. Dausse, JJ. Toulme, P. Faure , E. Peyrin, C. Ravelet

    Anal. Chem., 2016, 88, 2570-2575

  • Article • Recombinant tyrosinase from Polyporus arcularius: overproduction in Escherichia coli, characterization and use in a study of aurones as tyrosinase 

    E. Böhmová, M. Kotík, A. Křenková, P. Man, R. Haudecoeur, A. Boumendjel, R. Hardre, Y. Mekmouche, E. Courvoisier-Dezord, M. Réglier, L. Martínková

    J. Agric. Food Chem. 64, 2925-2931.

  • Article • Investigation of the Pyridinium Ylide—Alkyne Cycloaddition as a Fluorogenic Coupling Reaction [Full paper ]

    S. Bonte, I.O. Ghinea, R. Dinica, I. Baussanne, M. Demeunynck

    Molecules 2016, 21, 332

  • Article • Biocompatible Double-Membrane Hydrogels from Cationic Cellulose Nanocrystals and Anionic Alginate as Complexing Drugs Codelivery [Full paper ]

    Ning Lin, Annabelle Gèze, Denis Wouessidjewe, Jin Huang, and Alain Dufresne

    ACS Applied Materials & Interfaces 2016, 8(11), 6880-6889

  • Article • A combinatorial approach to the repertoire of RNA kissing motifs; toward multiplex detection by switching hairpin aptamers [Full paper ]

    G. Durand, E. Dausse, E. Goux, E. Fiore, E. Peyrin, C. Ravelet, J-J. Toulmé

    Nucleic Acids Res. 2016, 44, 4450-4459.

  • Article • New Pseudodimeric Aurones as Palm Pocket Inhibitors of Hepatitis C Virus RNA-dependent RNA Polymerase [Full paper ]

    Amel Meguellati, Abdelhakim Ahmed-Belkacem, Alessandra Nurisso, Wei Yi, Rozenn Brillet, Nawel Berqouch, Laura Chavoutier, Antoine Fortuné, Jean-Michel Pawlotsky, Ahcène Boumendjel, Marine Peuchmaur

    Eur. J. Med. Chem. 2016, 115, 217-229

  • Article • Small Molecule Aptamer Assays Based on Fluorescence Anisotropy Signal-Enhancer Oligonucleotides [Full paper ]

    S. Perrier, P. Bouilloud, G. de Oliveira Coelho, M. Henry, E. Peyrin

    Biosens. Bioelectron. 2016, 82, 155-161

  • Article • Capillary electrophoretic focusing of covalently derivatized protein induced by surfactant [Full paper ]

    F. Oukacine, J. P. Quirino, K. Mesbah, M. Taverna

    Electrophoresis 2016, 37, 1151-1154

  • Article • Nauclea latifolia: biological activities and alkaloid phyto-chemistry of a West African tree 

    B. Boucherle, R. Haudecoeur, E. Ferreira Queiroz, M. De Waard, J.-L. Wolfender, R. J. Robins, A. Boumendjel

    Nat. Prod. Rep. 2016, 33, 1034-1043

  • Article • New, highly potent and non-toxic, chromone inhibitors of the human breast cancer resistance protein ABCG2 

    A. R. Andrade Pires, F. Lecerf-Schmidt, J. Pazzinato, G. Jabor Gozzi, E. Winter, G. Valdameri, A. Veale, A. Boumendjel, A. Di Pietro, B. Pérès

    Eur. J. Med. Chem. 2016, 122, 291-301.

  • Article • Disruption of fibres from the AcPHF6 tau model by naturally occurring aurones and synthetic analogs 

    L. Lunven, H. Bonnet, S. Yahiaoui, L. Da Costa, M. Peuchmaur, A. Boumendjel, S. Chierici

    ACS Chem. Neurosci. 2016, 7, 995-1003.

  • Article • 2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2 [Full paper ]

    E. Baiceanu, K.-A. Nguyen, L. Gonzalez-Lobato, F. Loghin, M. Le Borgne, A. Boumendjel, M. Peuchmaur, P. Falson

    Eur. J. Med. Chem, 2016, 122, 408-418

  • Article • Detecting Alzheimer's Disease biomarkers: from antibodies to new bio-mimetic receptors and their application to established and emerging bioanalytical platforms - A critical review [Full paper ]

    S. Scarano, S. Lisi, C. Ravelet, E. Peyrin, M. Minunni

    Anal. Chim. Acta, 2016, 940, 21-37

  • Article • Arylthiosemicarbazones as antileishmanial agents [Full paper ]

    J. I. Manzano, F. Cochet, B. Boucherle, V. Gómez-Pérez, A. Boumendjel, F. Gamarro, M. Peuchmaur

    Eur. J. Med. Chem. 2016, 123, 161-170.

  • Article • "Rules of Engagement"of Protein-Glycoconjugate Interactions; A Molecular View Achievable by using NMR Spectroscopy and Molecular Modeling [Full paper ]

    R. Marchetti, S. Perez, A. Arda, A. Imberty, J. Jimenez-Barbero, A. Silipo & A. Molinaro

    Chemistry Open, 2016, 5, 274-296

  • Article • The Hidden Conformation of Lewis x, a Human Histo-Blood Group Antigen is a Determinant for Recognition by Pathogen Lectins [Full paper ]

    J. Topin, M. Lelimousin, J. Arnaud, A. Audfray; S. Perez, A. Varrot & A. Imberty

    ACS Chemical Biology, 2016, 11, 2011-2020

  • Article • The Plant Cell Walls 

    J-P. Joseleau & S. Perez

    glycopedia; www.glycopedia.eu/e-chapters/the-plant-cell-wall/article

  • Article • Synthesis of three series of ruthenium tris-diimine complexes containing acridine-based pi-extended ligands using an efficient “chemistry on the complex” approach [Full paper ]

    Jean-François Lefebvre, Dounia Saadallah, Philipp Traber, Stephan Kupfer, Stefanie Gräfe, Benjamin Dietzek, Isabelle Baussanne, Julien De Winter, Pascal Gerbaux, Cécile Moucheron, Murielle Chavarot-Kerlidou, Martine Demeunynck

    Dalton Trans. 2016, 45, 16298 – 16308

  • Article • Multiple capillary isotachophoresis with repetitive hydrodynamic injections for performance improvement of the electromigration preconcentration [Full paper ]

    T. Mai, F. Oukacine, M. Taverna

    J. Chromatogr. A 2016, 1543, 116-123

  • Article • Multi-analytical study of the binding between a small chiral molecule and a DNA aptamer: evidences for asymmetric steric effect upon 3’ vs. 5’-end sequence modification [Full paper ]

    L. Challier, R. Miranda-Castro, B. Barbe, C. Fave, B. Limoges, E. Peyrin, C. Ravelet, E. Fiore, P. Labbé, L. Coche-Guérente, E. Ennifar, G. Bec, P. Dumas, F. Mavré, V. Noël

    Anal. Chem. 2016, 88, 11963–11971

  • Article • New broad-spectrum antibacterial amphiphilic aminoglycosides active against resistant bacteria: From neamine derivatives to smaller neosamine analogues. [Full paper ]

    L. Zimmermann, I. Das, J. Desire, G. Sautrey, V. Barros R. S., M. El Khoury, M.-P. Mingeot-Leclercq, J.-L. Decout

    J. Med. Chem. 2016, 59, 9350-9369

  • Article • Mesoporous self-​assembled nanoparticles of biotransesterified cyclodextrins and nonlamellar lipids as carriers of water-​insoluble substances [Full paper ]

    Zerkoune, Leila; Lesieur, Sylviane; Putaux, Jean-Luc; Choisnard, Luc; Geze, Annabelle; Wouessidjewe, Denis; Angelov, Borislav; Vebert-Nardin, Corinne; Doutch, James; Angelova, Angelina

    Soft Matter, 2016, 12, 7539-7550

  • Article • The Hidden Conformation of Lewis x, a Human Histo-blood Group Antigen is a Determinant for Recognition by Pathogen Lectins 

    J Topin, M Lelimousin, J Arnaud, A Audfray, S Pérez, A Varrot,

    ACS Chem. Biol., 11, 2011−2020

  • Article • “Rules of Engagement” of Protein–Glycoconjugate Interactions: A Molecular View Achievable by using NMR Spectroscopy and Molecular Modeling 

    R Marchetti, S Perez, A Arda, A Imberty, J Jimenez‐Barbero, A Silipo, A Molinaro

    ChemistryOpen, 2016, (5) 274-296

  • Oral Comm • Une approche rationnelle pour la thérapie de la mucoviscidose 

    Benjamin Boucherle

  • Oral Comm • Deciphering the Multiscale Architecture of Biomaterials at Synchrotron Radiations Facilities (keynote lecture) 

    S. Perez

  • Oral Comm • Glycoinformatics: Databases and Software Tools for Glycosciences & Carbohydrate-Protein Interactions: Molecular Modeling Insights. 

    S. Perez

  • Oral Comm • Popular Glycoscience: Building, Seeing, Organizing and Playing with Complex Glycans (conférence invitée) 

    S. Perez

  • Oral Comm • Toolboxes for Standardized Investigations and Representations of Glycans (keynote lecture) 

    S.Perez

  • Oral Comm • From Monosaccharides to Polysaccharides. From Structures to 3D Databases. (keynote leture) 

    S. Perez

  • Oral Comm • Interoperability of gkycosaminoglycans databases through semantic web  

    S. Perez, F. Lisacek, J. Mariethoz, M. Deniau, N. Thierry-Mieg & S. Ricard Blum

  • Oral Comm • Dynamics of fucose and LewisX in lectin-binding sites 

    M. Lelimousin, J. Topin, J. Arnaud, A. Auffray, S. Perez, A. Varrot & A. Imberty

  • Oral Comm • Computational modeling of pure rhamnogalacturonan I capable to form self-aggregates, 

    O. Makshakova, P. Mikshina, S. Perez & T. Gorshkova

  • Oral Comm • Du crible phénotypique à l’optimisation de hit : cas du MBL II 141, un inhibiteur puissant et sélectif de la protéine BCRP 

    A. Boumendjel

  • Oral Comm • The indolizine: from bioactive heterocycle to fluorescent modular platform for cellular target identification 

    Martine Demeunynck*, Isabelle Baussanne, Simon Bonte, Marie Arvin-Berod, Rodica Dinica, Bianca Furdui, Ioana Ottilia-Ghinea

  • Oral Comm • Toolboxes for Standardized Investigations and Representations of Glycans 

    Serge Perez

  • Oral Comm • Glyco Bio Informatique: Standardisation et Représentations des Carbohydrates Complexes 

    Serge Pérez

  • Article • A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras 

    A. Desroches-Castan, D. Quélard, M. Demeunynck, JF Constant, C. Dong, M. Keramidas, JL Coll, C. Barette, L. Lafanechère, JJ Feig

    Oncotarget

  • Article • COB231 targets amyloid plaques in post-mortem human brain tissue and in an Alzheimer mouse model 

    D. Garin, A. Virgone-Carlotta, B. Gözel, F. Oukhatar, P. Perret, D. Marti-Battle, M. Touret, P. Millet, M. Dubois-Dauphin, D. Meyronet, N. Streichenberger, F. M. Laferla, M. Demeunynck, S. Chierici, M. Moulin Sallanon, C. Ghezzi

    J. Neurochem.

  • Article • IPP51, a novel microtubule inhibitor with in vivo antitumor activity against bladder carcinoma 

    V. Martel-Frachet, M. Keramidas, A. Nurisso, S. Debonis, C. Rome, J.-L. Coll, A. Boumendjel, D. Skoufias, X. Ronot

    Oncotarget

  • Article • Macrocyclic host-dye reporter for sensitive sandwich-type fluorescent aptamer sensor [Full paper ]

    Yang C, Spinelli N, Perrier S, Defrancq E, Peyrin E.

    Anal Chem. 2015, 87, 3139-3143.

  • Article • Chiral resolution capabilities of DNA oligonucleotides [Full paper ]

    L. Tohala, F. Oukacine, C. Ravelet, E. Peyrin

    Anal. Chem. 2015, 87, 5491-5495.

  • Article • An improved design of the kissing complex-based aptasensor for the detection of adenosine [Full paper ]

    E Goux, S Lisi, C Ravelet, G Durand, E Fiore, E Dausse, JJ Toulmé, E Peyrin

    Anal. Bioanal. Chem. 2015, 407, 6515-6524.

  • Article • A new straightforward synthesis of 2’, 3’-didehydro-2’, 3’-dideoxy-2’-(2”- (trimethylsilyl)ethylthio)thymidine, key intermediate for the synthesis of 2’-substituted thionucleosides 

    Maralise P. Oliveira, Lucas L. Franco, Maria C. A. Lima, Cláudia M. O. Simões, Suely L. Galdino, Ivan R. Pitta, Jean-Luc Décout, Ricardo J. Alves

    J. Braz. Chem. Soc. 26, 816-821, 2015

  • Article • A retro-biosynthetic approach to the prediction of biosynthetic pathways from position-specific isotope analysis as shown for tramadol. [Full paper ]

    Romek KM, Nun P, Remaud GS, Silvestre V, Taïwe GS, Lecerf-Schmidt F, Boumendjel A, De Waard M, Robins RJ.

    Proc. Natl. Acad. Sci. U. S. A. 2015, 112, 8296-301.

  • Article • Ultrafast Capillary Electrophoresis Isolation of DNA Aptamer for the PCR Amplification-Based Small Analyte Sensing  [Full paper ]

    E. Fiore, E. Dausse, H. Dubouchaud, E. Peyrin, C. Ravelet

    Front. Chem. 2015, 3, 49

  • Article • Optimisation of experimental parameters to explore small ligand-aptamer interactions by 1H NMR and molecular modelling [Full paper ]

    F. Souard, S. Perrier, V. Noel, C. Fave, E. Fiore, E. Peyrin, J. Garcia, C. Vanhaverbeke

    Chem. Eur. J. 2015, 21, 15740-15748

  • Article • Biomimetic Synthesis of Tramadol [Full paper ]

    F. Lecerf-Schmidt, R. Haudecoeur, B. Peres, M. M. Ferreira Queiroz, L. Marcourt, S. Challal, E. Ferreira Queiroz, G. Sotoing Taiwe, T. Lomberget, M. Le Borgne, J.-L. Wolfender, M. De Waard, R. J. Robins and A. Boumendjel

    Chem. Commun. 2015, 15, 14451-14453.

  • Article • Uncovering new structural insights for antimalarial activity from cost-effective aculeatin-like derivatives [Full paper ]

    Winkler, Matthias Maynadier, Marjorie Wein, Sharon Lespinasse, Marie-Ange Boumis, Giovanna Miele, Adriana E. Vial, Henri Wong, Yung-Sing

    Org. Biol. Chem. 2015, 13, 2064-2077

  • Article • Synthèse orientée vers la diversité structurale pour explorer le vivant  

    Yung-Sing Wong

    Med. Sci. 2015, 31, 93-97

  • Article • A novel platinum-maurocalcine conjugate induces apoptosis of human glioblastoma cells by acting through the ROS-ERK/AKT-p53 Pathway. 

    Aroui S, Dardevet L, W. BAjmia, M. de Boisvilliers, F. Perrin, A. Laajimi, A. Boumendjel, A. Kenani, J. M. Muller, M. de Waard.

    Mol Pharm. 2015, 12, 4336-4348.

  • Article • Size-based characterization of nanoparticle mixtures by the inline coupling of Capillary Electrophoresis to Taylor Dispersion Analysis [Full paper ]

    F. Oukacine, A. Morel, I. Desvignes, H. Cottet

    J. Chromatogr. A 2015, 1426, 220-225.

  • Article • Probing the acceptor active site organization of the human recombinant β1,4-galactosyltransferase 7 and design of xyloside-based inhibitors. [Full paper ]

    Saliba M, Ramalanjaona N, Gulberti S, Bertin-Jung I, Thomas A, Dahbi S, Lopin-Bon C, Jacquinet JC, Breton C, Ouzzine M, Fournel-Gigleux S

    J. Biol. Chem. 290, 7658-70

  • Article • Three-Dimensional Representations of Complex Carbohydrates and Polysaccharides. SweetUnityMol: A Video Game Based Computer Graphic Software 

    S. PEREZ, T. TUBIANA, A. IMBERTY & M. BAADEN

    Glycobiology, 25, 483-491

  • Article • GLYCO3D: A Portal for Structural Glycosciences [Full paper ]

    S. PEREZ, A. SARKAR, A. RIVET, C. BRETON & A. IMBERTY

    Glycoinformatics, Methods in Molecular Biology, 1273, 241-258

  • Article • Databases of Conformations and NMR Structures of Glycan Determinants [Full paper ]

    A. SARKAR, S. DROUILLARD, A. RIVET & S. PEREZ (2015)

    Glycobiology, 25, 1480-1490

  • Article • Negatively Charged Glyconanoparticles Modulates and Stabilize the Secondary Structures of a Gp120 V3 loop. Towards Full Synthetic HIV Vaccine Candidate 

    O. DI GIANVINCENZO, J. CALVO, S. PEREZ, A. ALVAREZ, L.M. BEDOYA, J. ALCAMI & S. PENADES

    Bioconjugate Chemistry, 26, 755-765.

  • Article • Symbol Nomenclature for Graphical Representation of Glycans 

    A. VARKI, R.D. CUMMINGS, M. AEBI, N.H. PARKER, P.H. SEEBERGER,..., S. PEREZ, E. BOLTON, P. RUDD, J. PAULSON, M. KANEHISA, P. TOUKACH, K.F. AOKI-KINOSHITA, A. DELL, H. NARIMATSU, W. YORK, N. TANIGUCHI & S. KORNFELD

    Glycobiology, 25, 1323-1324

  • Patent • Composés inhibiteurs de Pseudomonas aeruginosa 

    Yung-Sing Wong, Sophie Plé, Ina Attree, Caroline Barette

    2015 • CNRS/CEA

  • Book • Validation de la robustesse d'une méthode analytique par plan d'experiences 

    Morgan Germa, Luc Choisnard

    2015 • 1-4, - Paris

  • Oral Comm • Discovery of novel tailored F508del-CFTR binder correctors based on 3D structure models of entire CFTR protein for treating Cystic Fibrosis 

    Clément Boinot, Mathilde Jollivet Souchet, Brice Hoffmann, Jean-Paul Mornon, Benjamin Boucherle, Antoine Fortuné, Jean-Luc Decout, Pierre Lehn, Isabelle Callebaut, Frédéric Becq

  • Oral Comm • Models of the 3D structure of CFTR: from the understanding of the protein functions to the design of correctors  

    Brice Hoffmann, Jean-Paul Mornon, Benjamin Boucherle, Antoine Fortuné, Romain Haudecoeur, Clément Boinot, Mathilde Jollivet, Jean-Luc Decout, Frédéric Becq, Pierre Lehn, Isabelle Callebaut

  • Oral Comm • Popular Glycoscience: Building, Seeing, Organizing and Playing with Complex Glycans 

    M. Lelimousin, J. Topin, J. Arnaud, A. Auffray, S. Perez, A. Varrot & A. Imberty

  • Oral Comm • The Mystery of Starch Granule. A Multiscale Biomaterial (Plenary Lecture) 

    S. Perez

  • Oral Comm • Building, Seeing and Playing with Complex Glycans (Invited talk) 

    S. Perez

  • Oral Comm • Popular Glycoscience: Building, Seeing, Organizing and Playing with Complex Glycans 

    S. Perez

  • Article • Progress in developing amphiphilic cyclodextrin-based nanodevices for drug delivery 

    J. Yameogo, A. Geze, L. Choisnard, J-L. Putaux, S. Semde, D. Wouessidjewe

    Current Topics in medicinal chemistry, 14, 526-541

  • Article • Quantitative evaluation of the combination between cytotoxic drug and efflux transporter inhibitors based on a tumour growth inhibition model 

    A. Sostelly, L. Payen, J. Guitton, A. Di Pietro, P. Falson, M. Honorat, A. Boumendjel, A. Geze, G. Freyer, M. Tod

    Fundamental & Clinical Pharmacology, 2014, 28, 161-9.

  • Article • Catalytic DNA-Based Fluorescence Polarization Chiral Sensing Platform for L-Histidine Detection at Trace Level [Full paper ]

    N. Braga Amaral, S. Zuliani, V. Guieu, C. Ravelet, S. Perrier, E. Peyrin.

    Anal. Bioanal. Chem. 2014, 406, 1173-1179.

  • Article • Bioguidage search of active compounds from Waltheria indica L. (Malvaceae) used for asthma and inflammation treatment in Burkina Faso. 

    F. Zongo, C. Ribuot, A.Boumendjel, I.Guissou

    Fundam Clin Pharmacol. 2014, 28, 323-330.

  • Article • Nauclea latifolia Smith (Rubiaceae) exerts antinociceptive effects in neuropathic pain induced by chronic constriction injury of the sciatic nerve. [Full paper ]

    G. Sotoing Taïwe, E. Ngo Bum, E. Talla, T. Dimo, A. Dawe, V. Sinniger, B. Bonaz, A. Boumendjel and M. De Waard.

    J. Ethnopharmacol. 2014, 151, 445-451.

  • Article • Achilles compounds inducing selective apoptosis of resistant cancer cells overexpressing multidrug ABC transporters: a new therapeutic strategy? 

    G. Szakacs, M. M. Gottesman, A. Boumendjel, R. Kachadourian, B. J. Day, L. Payen, H. Cortay & A. Di Pietro

    Chem. Rev, 2014, 114, 5753-74.

  • Article • Riboswitches Based on Kissing Complexes for the Detection of Small Ligands. [Full paper ]

    G. Durand, S. Lisi, C. Ravelet, E. Dausse, E. Peyrin, JJ. Toulmé.

    Angew. Chem. Int. Ed. 2014,53,6942-6945.

  • Article • Investigation of the Binding-Site Homology of Mushroom and Bacterial Tyrosinases by Aurones as Effectors 

    R. Haudecoeur,A. Gouron,C. Dubois, H. Jamet, M. Lightbody, R. Hardré, A. Milet, E. Bergantino, L. Bubacco, C. Belle, M. Réglier, A. Boumendjel

    ChemBioChem, 2014, 15, 1325-33.

  • Article • B-ring modified aurones as promising allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase. 

    A. Meguelatti, A. Ahmed-Belkacem, W. Yi, R. Haudecoeur, M. Crouillère, R. Brillet, J.-M. Pawlotsky, A. Boumendjel, M. Peuchmaur

    Eur. J. Med. Chem. 2014, 80, 579-592.

  • Article • Capillary Gel Electrophoresis-Coupled Aptamer Enzymatic Cleavage Protection Strategy for the Simultaneous Detection of Multiple Small Analytes [Full paper ]

    S. Perrier, Z. Zhu, E. Fiore, C. Ravelet, V. Guieu, E. Peyrin.

    Anal. Chem. 2014, 86, 4233-4240.

  • Article • Collateral sensitivity of resistant MRP1 overexpressing cells to flavonoids and derivatives through GSH efflux 

    D. Lorendeau, E. Genoux-Bastide, L. Dury, F. Lecerf-Schmidt, R. Terreux, S. Magnard, A. Di Pietro, A. Boumendjel, H. Baubichon-Cortay

    Biochem. Pharmacol. 2014, 90, 235-45.

  • Article • A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo. 

    B. Boucherle, J. Bertrand, B. Maurin, B.-L. Renard, A. Fortuné, B. Tremblier, F. Becq, C. Norez, J.-L. Decout.

    Eur. J. Med. Chem. 2014, 83, 455-465.

  • Article • Electrochemical transduction of DNA hybridization at modified electrodes by using an electroactive pyridoacridone intercalator 

    L. Bouffier, B. Wang, A. Roget, T. Livache, M. Demeunynck, P. Mailley

    Anal. Bioanal. Chem. 2014, 406, 1163-1172

  • Article • Synthesis and in vivo evaluation of new N-heterocyclic diquaternary pyridinium compounds 

    B. Furdui, G. Parfene, I. O. Ghinea, R. M. Dinica, G. Bahrim, M. Demeunynck

    Molecules 2014, 19, 11572-11585

  • Article • Exploring the interaction of N/S compounds with dicopper center: from model studies to tyrosinase inhibition. 

    E. Buitrago, A. Vuillamy, A. Boumendjel, W. Yi, G. Gellon, R. Hardré, G. Serratrice, M. Réglier, C. Belle

    J. Inorg. Chem. (acceptée)

  • Article • MBL-II-141 enhances irinotecan anticancer efficiency in ABCG2 positive xenografts. 

    M. Honorat, J. Guitton, C. Gauthier, C. Bouard, R. Terreux, H. Gervot, C. Rioufol, A. Boumendjel, A. Puisieux, A. Di Pietro, L. Payen Lea

    Oncotarget, (acceptée)

  • Article • Use of a fractional factorial design to study the effects of experimental factors on the chitin deacetylation. [Full paper ]

    I. Younes, O. Ghorbel-Bellaaj, M. Chaabouni, M. Rinaudo, F. Souard, C. Vanhaverbeke, K. Jellouli, M. Nasri

    Int. J. Biol. Macromol. 2014, 70, 385-90.

  • Article • Self-assembled biotransesterified cyclodextrins as potential Artemisinin nanocarriers. II: In vitro behavior toward the immune system and in vivo biodistribution assessment of unloaded nanoparticles [Full paper ]

    J. B.G. Yaméogo, A. Gèze, L. Choisnard, J-L Putaux, R. Mazet, C. Passirani, M. Keramidas, J-L Coll, N. Lautram, J. Bejaud, R. Semdé, D. Wouessidjewe

    European Journal of pharmaceutics and biopharmaceutics, 88, 683-694

  • Article • New amphiphilic neamine derivatives active against resistant Pseudomonas aeruginosa and their interactions with lipopolysaccharides [Full paper ]

    Guillaume Sautrey, Louis Zimmermann, Magali Deleu, Alicia Delbar, Luiza Souza Machado, Katy Jeannot, Françoise Van Bambeke, Julien M. Buyck, Jean-Luc Decout, Marie-Paule Mingeot-Leclercq

    Antimicrob. Agents Chemother. 2014, 58, 4420-4430.

  • Article • Physico-chemical characterization of polymeric micelles loaded with platinum derivatives by capillary electrophoresis and related methods [Full paper ]

    F. Oukacine, S. Bernard, I. Bobe, H. Cottet

    J. Control. Release 2014, 196, 139-145.

  • Article • An improved capillary electrophoresis method for in vitro monitoring of the challenging early steps of A beta(1-42) peptide oligomerization: Application to anti-Alzheimer's drug discovery [Full paper ]

    D. Brinet, J. Kaffy, F. Oukacine, S. Glumm, S. Ongeri, M. Taverna

    Electrophoresis 2014, 35, 3302-3309.

  • Article • Poly(glycidyl methacrylate)/silver nanocomposite microspheres as a radioiodine scavenger: Electrophoretic characterisation of carboxyl- and amine-modified particles [Full paper ]

    H. Mackova, F. Oukacine, Z. Plichta, M. Hruby, J. Kucka, M. Taverna, D. Horak

    J. Colloid Interface Sci. 2014, 421, 146-153.

  • Article • Suppression of Apparent Fluid Flow in Capillary Isotachophoresis without Recourse to Capillary Coating [Full paper ]

    F. Oukacine, M. Taverna

    Anal. Chem. 2014, 86, 3317-3322

  • Article • Protein-Carbohydrate interactions: Molecular Modeling Insights 

    S. Perez & I. Tvaroska

    Advances in Carbohydrate Chemistry and Biochemistry, 71, 9-136

  • Patent • Compounds for treating cystic fibrosis 

    Isabelle Callebaut, Jean-Paul Mornon, Jean-Luc Decout, Frédéric Becq, Pierre Lehn, Brice Hoffmann, Benjamin Boucherle, Romain Haudecoeur, Antoine Fortuné, Clément Boinot, Julien Alliot

    2014 • 

  • Article • A template model for studying anticancer drug efflux transporter inhibitors in vitro. 

    A. Sostelly, L. Payen, J. Guitton, A. Di Pietro, P. Falson, M. Honorat, G. Valdamieri, A. Geze, A. Boumendjel, G. Freyer, M. Tod

    Fundamental & Clinical Pharmacol. 2013, 27, 544-56.

  • Article • Structure-Activity Relationships in the Development of Allosteric Hepatitis C Virus RNA-Dependent RNA Polymerase Inhibitors: Ten Years of Research [Full paper ]

    R. Haudecoeur, M. Peuchmaur, A. Ahmed-Belkacem, J.-M. Pawlotsky,A. Boumendjel

    Med. Res. Rev. 2013, 33, 934-984.

  • Article • Microfluidic Channel with Embedded SERS 2D Platform for the Aptamer Detection of Ochratoxin A [Full paper ]

    B. C. Galarreta, M. Tabatabaei, V. Guieu, E. Peyrin, F. Lagugne-Labarthet

    Anal. Bioanal. Chem. 2013, 405, 1613-1621

  • Article • 3-Aryl-4-methyl-2-quinolones targeting multiresistant Staphylococcus aureus bacteria. 

    A. Doléans-Jordheim, J.-B. Veron, O. Fendrich, E. Bergeron, A. Montagut-Romans, Y.-S. Wong, B. Furdui, J. Freney, C. Dumontet, A. Boumendjel

    ChemMedChem, 2013, 8, 652-657.

  • Article • Novel one-pot green synthesis of indolizines biocatalyzed by Candida antartica lipases 

    R. M. Dinica, B. Furdui, I. O. Ghinea, G. Bahrim, S. Bonte, M. Demeunynck

    Mar. Drugs, 2013, 11, 431-439

  • Article • Survey of recent literature related to the biologically active 4(3H)-quinazolinones containing fused heterocycles 

    M. Demeunynck, I. Baussanne

    Curr. Med. Chem. 2013, 20, 794-814

  • Article • Botany, traditional uses, phytochemistry and pharmacology of Waltheria indica L. (Syn. Waltheria americana. 

    F. Zongo,C. Ribuot, A. Boumendjel, I. Guissou

    J Ethnopharmacology, 148, 14-26.

  • Article • Breast Cancer Resistance Protein (BCRP/ABCG2): discovery of potent and highly selective inhibitors. 

    F. Lecerf-Schmidt, B. Peres, G. Valdameri,L. Payen, A. Di Pietro, A. Boumendjel

    Future Med. Chem. 2013, 5, 1037-1045.

  • Article • Investigation of the lipase catalysed reaction of aliphatic amines with ethyl propiolate as a route to N-substituted propiolamides 

    S. Bonte, I. O. Ghinea, I. Baussanne, J.-P. Xuereb, R. Dinica, M. Demeunynck

    Tetrahedron, 2013, 69, 5495-5500

  • Article • Occurrence of the synthetic analgesic tramadol in an african medicinal plant [Full paper ]

    A. Boumendjel, G. Sotoing Tawe, E. Ngo Bum, Tanguy Chabrol, C. Beney, V. Sinniger, R. Haudecoeur, L. Marcourt, S. Challal, E. Ferreira Queiroz, F. Souard, M. Le Borgne, T. Lomberget, A. Depaulis, C. Lavaud, R. Robins, J.-L. Wolfender, B. Bonaz, M. De Waar

    Angewandte Chemie Int. Ed. 2013, 52, 11780–11784.

  • Article • Identification of novel specific reversal agents of the Leishmania LABCI4 transporter through screening and optimization of flavonoid and trolox derivatives. 

    J. Ignacio Manzano, F. Lecerf-Schmidt, M.-A. Lespinasse, A. Di Pietro, S. Castanys, A. Boumendjel, F. Gamarro

    Antimicrob Agents Chemotherapy. 2013, 57, 3719-3730.

  • Article • AG11, a novel dichloroflavanone derivative with antimitotic activity towards human bladder cancer cells. 

    A. Juhem; A. Boumendjel, B. Touquet, A. Guillot, A. Popov, X. Ronot, V. Frachet

    Anticancer Research, 2013, 33, 4445-4452.

  • Article • Glycosidase inhibition by novel guanidinium and urea iminosugar derivatives 

    R. Kooij, H.M. Branderhorst, S. Bonte, S. Wieclawska, N.I. Martin, R.J. Pieters

    Med. Chem. Commun. 2013, 4, 387-393

  • Article • Tuning the antibacterial activity of amphiphilic neamine derivatives and comparison to paromamine homologues. [Full paper ]

    L. Zimmermann, A. Bussiere, M. Ouberai, I. Baussanne, C. Jolivalt, M.-P. Mingeot-Leclercq, J.-L. Decout.

    J. Med. Chem. 2013, 56, 7691-7705.

  • Article • Investigation of the cellular and molecular mechanisms activating the cell death processes by chalcones: critical structural effects. 

    P. Champelovier, X. Chauchet, F. Hazane-Puch, C. Garrel, V. Curri, L. François, J. Boutonnat and A. Boumedjel.

    Toxicology in Vitro. 2013, 27, 2305-2315.

  • Article • New 7-methylguanine derivatives targeting the influenza PB2 cap-binding domain. [Full paper ]

    S. Pautus, P. Sehr, J. Lewis, A. Fortuné, A. Wolkerstorfer, O. Szolar, D. Guilligay, T. Lunardi, J.-L. Decout, S. Cusack.

    J. Med. Chem. 2013, 56, 8915-8930.

  • Article • Antibiotic drugs aminoglycosides cleave DNA at abasic sites: Shedding new light on their toxicity? [Full paper ]

    M. Perigolo, J.-F. Constant, M. Peuchmaur, I. Pitta, J.-L. Decout.

    Chem. Res. Tox. 2013, 26, 1710–1719.

  • Article • Structure-activity relationships of chromone derivatives toward mechanism of interaction with, and inhibition of, breast cancer resistance protein ABCG2 

    E. Winter, F. Lecerf-Schmidt, B. Peres, M. Lightbody, C. Gauthier, C. Ozvegy-Laczka, B. Sarkadi, T. Creczynski-Pasa, A. Boumendjel, A. Di Pietro.

    J. Med. Chem. 56, 9849-9860.

  • Article • β-Cyclodextrin–Glycerol Dimers: Synthesis and NMR Conformational Analysis 

    V. Legros, C. Vanhaverbeke, F. Souard, C. Len, J. Desire

    Eur. J. Org. Chem. 2013, 13, 2583–2590.

  • Article • Bioesterified polysubstituted-cycloedxtrin/surfactant nanoparticles obtained by multilevel self-assembly 

    L.Zerkoune, A. Angelova, L. Choisnard, A. Gèze, D. Wouessidjewe, S. Lesieur

    ICOMF14 Proceedings, MATEC Web of conferences, 2013, 4, 05001

  • Article • Identification of PDZ ligands by docking-based virtual screening for the development of novel analgesic agents  [Full paper ]

    Naoual Bouzidi, Hemantkumar Deokar, Alexandre Vogrig, Benjamin Boucherle, Isabelle Ripoche, Isabelle Abrunhosa-Thomas, Liam Dorr, Anne-Sophie Wattiez, Lu-Yun Lian, Philippe Marin, Christine Courteix, Sylvie Ducki

    Bioorganic & medicinal chemistry letters 03/2013; 23(9)

  • Article • Structure-Based Design of PDZ Ligands as Inhibitors of 5-HT2A Receptor/PSD-95 PDZ1 Domain Interaction Possessing Anti-hyperalgesic Activity [Full paper ]

    Alexandre Vogrig, Liam Dorr, Naoual Bouzidi, Benjamin Boucherle, Anne-Sophie Wattiez, Elisabeth Cassier, Gary Vallon, Isabelle Ripoche, Isabelle Abrunhosa-Thomas, Philippe Marin, Lionel Nauton, Vincent Thery, Christine Courteix, Lu-Yun Lian, Sylvie Ducki

    ACS Chemical Biology 07/2013; 8(10), 2209 − 2216

  • Article • On-line capillary electrophoresis derivatization method for high sensitivity analysis of ubiquitin in filtered cerebrospinal fluid [Full paper ]

    K. Mesbah, F. Oukacine, S. Lehnert, M. Otto, M. Taverna

    Electrophoresis 2013, 34, 2733-2739.

  • Article • Study of interactions between oppositely charged dendrigraft poly-L-lysine and human serum albumin by continuous frontal analysis capillary electrophoresis and fluorescence spectroscopy [Full paper ]

    N. Sisavath, L. Leclercq, T. Le Saux, F. Oukacine, H. Cottet

    J. Chromatogr. A 2013, 1289, 127-132.

  • Article • Monitoring surface functionalization of dendrigraft poly-L-lysines via click chemistry by capillary electrophoresis and Taylor dispersion analysis [Full paper ]

    T. Liu, F. Oukacine, H. Collet, A. Commeyras, L. Vial, H. Cottet

    J. Chromatogr. A 2013, 1273, 111-116.

  • Article • Flexible synthesis and evaluation of diverse anti-Apicomplexa cyclic peptides. 

    Traore M., Mietton F., Maubon D., Peuchmaur M., Fancisco Hilario F., Pereira de Freitas R., Bougdour A., Curt A., Maynadier M., Vial H., Pelloux H., Hakimi M.-A., Wong, Y.-S.

    J. Org. Chem. 2013, 78, 3655-3675

  • Article • Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein. 

    Peuchmaur M., Lacour M.-A., Sevalle J., Lisowski V., Touati-Jallabe Y., Rodier F., Martinez J., Checler F., Hernandez J.-F.

    Bioorg. Med. Chem. 2013, 21, 1018-1029.

  • Patent • Kits-of-parts comprising nucleic acids able to form a kissing complex and their uses thereof 

    G. Durand, C. Ravelet, E. Dausse, E. Peyrin, JJ. Toulmé

    2013 • Inserm, UJF, CNRS

  • Patent • Nouveaux dérivés de chalcone présentant une activité anti-allergique 

    A. Boumendjel, G. Monneret, C. Dumontet

    2013 • UJF, CNRS, Inserm, UCBL

  • Patent • Extraction of tramadol from Nauclea Latifolia from Cameroon. 

    G. Sotoing Taïwe, A. Boumendjel, M. De Waard

    2013 • Inserm, UJF, CNRS

  • Patent • Facteur X dépourvu de domain GLA  

    A. Thomas, M-C. Dagher, R. Marlu, B. Polack

    2013 • 

  • Patent • Procédé de préparation de compositions de polysaccharides bactériens, de mouts de fermentation les comprenant, et les utilisations desdites compositions. [Full paper ]

    S. Crapart, C. Ernenwein, A. Bresin, K. Logeat, T. Heulin, W. Achouak, A. Heyraud, C. Vanhaverbeke

    2012 • 

  • Article • Monodisperse nanoparticles from self-assembling amphiphilic cyclodextrin: modulable tools for the encapsulation and controlled release of pharmaceuticals 

    A. Mendez-Ardoy, M. Gomez Garcia, A. Geze, J.-L. Putaux, D. Wouessidjewe, C. Ortiz Mellet, J. Defaye, J. M. Garcia Fernandez, J. M. Benito

    Med. Chem. 2012, 8, 524-532.

  • Article • Versatile effects of aurone structure on the mushroom Tyrosinase activity 

    C. Dubois, R. Haudecoeur, M. Orio, C. Belle, C. Bochot, A. Boumendjel, R. Hardré, H. Jamet, M. Réglier

    ChemBioChem. 2012, 13, 559-565.

  • Article • Substituted chromones as highly-potent nontoxic inhibitors, specific for the breast cancer resistance protein ABCG2. 

    G. Valdameri, E. Genoux-Bastide, B. Peres, R. Terreux, C. Gauthier, J. Guitton, S. M. B. Winnischofer, M. Rocha, A. Boumendjel, A. Di Pietro

    J. Med. Chem.2012, 55, 966–970.

  • Article • A Synthetic chalcone derivative is a potent inducer of glutathione biosynthesis. 

    R. Kachadourian, B. J. Day, S. Pugazhenti, C. C. Franklin, E. Genoux-Bastide, G. Mahaffey, C. Gauthier, A. Di Pietro, A. Boumendjel

    J. Med. Chem. 2012, 55, 1382-8.

  • Article • Self-assembled biotransesterified cyclodextrins as artemisinin nanocarriers - I : Formulation, lyoavailability and in vitro antimalarial activity assessment 

    Josias B.G. Yameogo, c, Annabelle Geze, , Luc Choisnard, Jean-Luc Putaux, Adama Gansane, Sodiomon B. Sirimad, Rasmane Semde, Denis Wouessidjewe

    Eur. J. Pharm. Biopharm, 2012, 80(3), 508-517.

  • Article • Major increase of the reactivity and selectivity in aminoglycoside O-alkylation due to the presence of fluoride ions. [Full paper ]

    O. Jackowski, A. Bussière, C. Vanhaverbeke, I. Baussanne, E. Peyrin, M.-P. Mingeot-Leclercq, J.-L. Decout.

    Tetrahedron 2012, 68, 737-746.

  • Article • Investigation of chalcones as inhibitors of ABCG2: identification of structural frameworks required for both potent inhibition and selectivity. 

    C. Gauthier, G. Valdameri, R. Terreux, R. Kachadourian, B. J. Day, Sheila M. B. Winnischofer, M. E. M. Rocha, V. Frachet, X. Ronot, A. Di Pietro, A. Boumendjel.

    J. Med. Chem. 2012, 55, 3193-3200.

  • Article • Recent Advances in the Medicinal Chemistry of Aurones 

    R. Haudecoeur, A. Boumendjel

    Curr. Med. Chem. 2012,19, 2861-2875.

  • Article • 6-Halogenochromones bearing tryptamine: one step access, potent and highly selective inhibitors of breast cancer resistance protein. 

    G. Valdameri, E. Genoux-Bastide, C. Gauthier, R. Terreux, S. M. B. Winnischofer, M. E. M. Rocha, A. Di Pietro, A. Boumendjel

    ChemMedChem. 2012, 7, 1177-1180.

  • Article • A rapid, simple, and highly enantioselective electrochemical aptamer-based binding assay for trace detection of chiral compounds [Full paper ]

    L. Challier, F. Mavre, J. Moreau, C. Fave, B. Schollhorn, D. Marchal, E. Peyrin, V. Noel, B. Limoges

    Anal. Chem. 2012, 84, 5415-5420.

  • Article • Chalcone JAI-51 improves efficacy of synchrotron microbeam radiation therapy of brain tumors 

    A. Bouchet, A. Boumendjel, E. Khalil, R. Serduc, E. Brauer, E. A. Siegbahn, G. Le Duc, J.- A. Laissue, Jean Boutonnat

    J. Synchrotron Radiat. 2012, 19, 478-482.

  • Article • A Peptide Nucleic Acid-aminosugar conjugate targeting transactivation response element of HIV-1 RNA genome shows a high bioavailability in human cells and strongly inhibits tat-mediated transactivation of HIV-1. [Full paper ]

    I. Das, J. Desire, D. Manvar, I. Baussanne, V. N. Pandey, J.-L. Decout.

    J. Med. Chem. 2012, 55, 6021-6032.

  • Article • Single-Stranded DNA Binding Protein-Assisted Fluorescence Polarization Aptamer Assay for Detection of Small Molecules [Full paper ]

    Z. Zhu, C. Ravelet, S. Perrier, V. Guieu, E. Fiore, E. Peyrin.

    Anal. Chem. 2012, 84, 7203-7211.

  • Article • Electrochemistry and bioactivity relationship of 6-substituted-4H-pyrido[4,3,2-kl]acridin-4-one antitumor drug candidates 

    L. Bouffier, I. Gosse, M. Demeunynck, P. Mailley

    Bioelectrochem. 2012, 88, 103-109

  • Article • Catalyst-free synthesis of quinazolin-4-ones from (hetero)aryl-guanidines: application to the synthesis of pyrazolo[4,3-f]quinazolin-9-ones, a new family of DYRK1A inhibitors 

    J. Debray, S. Bonte, O. Lozach, L. Meijer, M. Demeunynck

    Mol. Divers. 2012, 16, 659-667

  • Article • Polycationic amphiphilic cyclodextrins as gene vectors: effect of the macrocyclic ring size on the DNA complexing and delivery properties 

    C. Bienvenu, A. Martinez, J.L. Jimenez Bianco, C. Di Giorgio, P. Vierling, C. Ortiz Mellet, J. defaye, J.M. Garcia Fernandez

    Org. Biomol. Chem., 20012, 10, 5570-5581.

  • Article • Field enhanced bacterial sample stacking in isotachophoresis using wide-bore capillaries [Full paper ]

    F. Oukacine, J. P. Quirino, D. Destoumieux-Garzon, H. Cottet

    J. Chromatogr. A 2012, 1268, 180-184.

  • Article • Taylor dispersion analysis with two detection points on a commercial capillary electrophoresis apparatus [Full paper ]

    J. Chamieh, F. Oukacine, H. Cottet

    J. Chromatogr. A 2012, 1235, 174-177.

  • Article • Study of Antibacterial Activity by Capillary Electrophoresis Using Multiple UV Detection Points [Full paper ]

    F. Oukacine, B. Romestand, D. M. Goodall, G. Massiera, L. Garrelly, H. Cottet

    Anal. Chem. 2012, 84, 3302-3310.

  • Book • Exploring chemical space: recent advances in chemistry [Full paper ]

    Yung-Sing Wong

    2012 • 11-23,

  • Thesis • Synthèse et évaluation de composés antipaludiques et antitoxoplasmoses 

    Mariam Traoré

    2012 • 

  • Article • Identification of Xanthones as Selective Killers of Cancer Cells Overexpressing the ABC Protein, MRP1 

    E. Genoux-Bastide, D. Lorendeau, E. Nicolle,S. Yahiaoui,S. Magnard,A. Di Pietro,H. Baubichon-Cortay,A. Boumendjel

    ChemMedChem. 2011, 6, 1478-1484.

  • Article • Copper(II)-complex directed regioselective mono-p-toluenesulfonylation of cyclomaltoheptaose at a primary hydroxyl group position: an NMR and molecular dynamics-aided design 

    H. Law, J. M. Benito, J. M. Garcia Fernandez, L. Jicszinsky, S. Crouzy, J. Defaye

    J. Phys. Chem. B, 2011, 115, 7524-7532.

  • Article • Discovery of the Naturally Occurring Aurones as Potent and non Toxic Allosteric Inhibitors of Hepatitis C Virus Polymerase(NS5B) 

    R. Haudecoeur, A. Ahmed-Belkacem, W. Yi, A. Fortune, R. Brillet, C. Belle, E. Nicolle, J.-M. Pawlotsky, A. Boumendjel

    J. Med. Chem. 2011, 54, 5395–5402.

  • Article • Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery. 

    A. Diaz-Moscoso, N. Guilloteau, C. Bienvenu, A. Mendez-Ardoy, J. L. Jiménez Bianco, J. M. Benito, L. Le Gourriérec, C. Di Giorgo, P. Vierling, J. Defaye, C. Ortiz Mellet, J. M. Garcia Fernandez

    Biomaterials, 2011, 32, 7263-7273.

  • Article • Dicer-Mediated Upregulation of BCRP Confers Tamoxifen Resistance in Human Breast Cancer Cells 

    J. Selever, M.T. Lewis, A. Beyer, I. Barone, G. Dontu, P. Provost, A. Di Pietro, A. Boumemdjel, K. Albain, L. Miele, H. Weiss, S. A. W. Fuqua

    Clinical Cancer Research. 2011, 17, 6510-6521.

  • Article • Refinement of Arylthiosemicarbazone Pharmacophore in Inhibition of Mushroom Tyrosinase 

    W. Yi, C. Dubois, S. Yahiaoui, R. Haudecoeur, C. Belle, H. Song, R. Hardré, M. Réglier and A. Boumendjel

    Eur. J. Med. Chem. 2011, 46, 4330-4335.

  • Article • Physicochemical Characterization of of a-, β-, and γ-Cyclodextrins Bioesterified with Decanoate Chains Used As Building Blocks of Colloidal Nanoparticles 

    L. Choisnard, A. Gèze, C. Vanhaverbeke, J. B. G. Yamogo, J.-L. Putaux, B. Brasme, L. Jullien, S. Boullanger, C. Elfakir, D. Wouessidjewe

    Biomacromolecules, 2011, 12(8), 3031-3038.

  • Article • Aptamer Enzymatic Cleavage Protection Assay for the Gold Nanoparticle-Based Colorimetric Sensing of Small Molecules. [Full paper ]

    V. Guieu, C. Ravelet, S. Perrier, Z. Zhu, S. Cayez, E. Peyrin.

    Anal. Chim. Acta 2011, 706, 349-353.

  • Article • A Straightforward conversion of Aurones to 2-Benzoylbenzofuranes: Transformation of One Class of Natural Products into Another 

    S. Yahiaoui, M. Peuchmaur, A. Boumendjel

    Tetrahedron, 2011, 67, 7703-7707

  • Article • Forming Spirocyclohexadienone-oxocarbenium cation species in the biomimetic synthesis of amomols. 

    M. Traore, M. Maynadier, F. Souard, L. Choisnard, H. Vial, Y.-S. Wong

    J. Org. Chem. 2011, 76, 1409-1417.

  • Article • Optimization of the Structure-Switching Aptamer-Based Fluorescence Polarization Assay for the Sensitive Tyrosinamide Sensing [Full paper ]

    Z. Zhu, T. Schmidt, M. Mahrous, V. Guieu, S. Perrier, C. Ravelet, E. Peyrin.

    Anal. Chim. Acta 2011, 707, 191-196.

  • Article • Fluorescence polarization biosensor based on aptamer enzymatic cleavage protection strategy [Full paper ]

    A. Kidd, V. Guieu, S. Perrier, C. Ravelet, E. Peyrin

    Anal. Bioanal. Chem. 2011, 401, 3229-3234.

  • Article • Utilisation des aptamères pour la détection de petites molécules par polarisation de fluorescence 

    V. Guieu, C. Ravelet, S. Perrier, E. Peyrin

    Spectra analyse 2011, 282, 24-31

  • Article • Structural requirement of arylindolylpropenones as anti-bladder carcinoma cells agents. 

    V. Martel-Frachet, M. Kadri, A. Boumendjel, X. Ronot.

    Bioorg. Med. Chem. 2011, 19, 6143-6148.

  • Article • Proflavine derivatives as fluorescent imaging agents of amyloid desposits 

    D. Garin, F. Oukhatar, A. B. Mahon, A. C. Try, M. Dubois-Dauphin, F. M. Laferia, M. Demeunynck, M. M. Sallanon, S. Chierici

    Bioorg. Med. Chem. Lett., 2011, 21, 2203-2206

  • Article • In vivo study and validation of novel pharmacological modulators of water and ionic intestinal secretion for future therapeutic applications. 

    L. Dannhoffer, J.-L. Decout, F. Becq.

    Fund. Clin. Pharmacol. 2011, 25, 79.

  • Article • The acridone derivative MBLI-87 reverses breast cancer resistance protein-mediated resistance to irinotecan in xenografts. 

    O. Arnaud, A. Boumendjel, A. Geze, P. Falson, C. Dumontet, A. Di Pietro, L. Payen

    Eur. J. Cancer, 2011, 47, 640-648.

  • Article • Synthesis and evaluation of bidentate ligands designed to interact with PDZ domains [Full paper ]

    Benjamin Boucherle, Alexandre Vogrig, Hemantkumar Deokar, Naoual Bouzidi, Isabelle Ripoche, Isabelle Thomas, Philippe Marin, Sylvie Ducki

    Bioorganic & medicinal chemistry 05/2011; 19(14):4346-54

  • Article • NMR evaluation of interactions between substituted-indole and PDZ1 domain of PSD-95 [Full paper ]

    Alexandre Vogrig, Benjamin Boucherle, Hemantkumar Deokar, Isabelle Thomas, Isabelle Ripoche, Lu-Yun Lian, Sylvie Ducki

    Bioorganic & medicinal chemistry letters 06/2011; 21(11):3349-53

  • Article • Simultaneous Electrokinetic and Hydrodynamic Injection for High Sensitivity Bacteria Analysis in Capillary Electrophoresis [Full paper ]

    F. Oukacine, J. P. Quirino, L. Garrelly, B. Romestand, T. Zou, H. Cottet

    Anal. Chem. 2011, 83, 4949-4954.

  • Article • Characterization of Carboxylated Nanolatexes by Capillary Electrophoresis [Full paper ]

    F. Oukacine, A. Morel, H. Cottet

    Langmuir 2011, 27, 4040-4047.

  • Article • Focusing and Mobilization of Bacteria in Capillary Electrophoresis [Full paper ]

    F. Oukacine, L. Garrelly, B. Romestand, D. M. Goodall, T. Zou, H. Cottet

    Anal. Chem. 2011, 83, 1571-1578.

  • Article • Symmetry complementarity-guided design of anthrax toxin inhibitors based on beta-cyclodextrin: Synthesis and relative activities of face-selective functionalized polycationic clusters 

    A. Diaz-Moscoso, A. Méndez-Ardoy, F. Ortega-Caballero, J.M. Benito, C. Ortiz-Mellet, J. Defaye, T.M. Robinson, A. Yohannes, V. A. Karginov, J.M. Garcia Fernandez

    ChemMedChem, 2011, 6, 181-192.

  • Article • The effect of flavonoid derivatives on doxorubicin-related formation of hydroxyl radicals. 

    P. Soucek, E. Kondrova, P. Stopka, A. Boumendjel, Y.-F. Ueng, I. Gut.

    Anti-Cancer Drugs, 2011, 22, 176-184.

  • Article • The acridone derivative MBLI-87 reverses breast cancer resistance protein-mediated resistance to irinotecan in xenografts. 

    O. Arnaud, A. Boumendjel, A. Geze, P. Falson, C. Dumontet, A. Di Pietro, L. Payen

    E. J. Cancer, 2011, 47, 640-648.

  • Article • Le sucre, source de vie, d'énergie ..., et de plaisir. 

    J. Defaye

    http://www.cnrs.fr/chimie2011, contribution du CNRS à l\\\'AIC 2011.

  • Article • Investigation of low energy proton effects on aptamer performances for astrobiological applications 

    M. Bacqué,A. Le Postollec,C. Ravelet,E. Peyrin, G. Coussot,I. Desvignes,S. Incerti, P. Moretto,M. Dobrijevic,O. Vandenabeele-Trambouze.

    Astrobiology 2011, 11, 207-211.

  • Article • The Pseudomonas aeruginosa membranes: a target for a new amphiphilic aminoglycoside derivative? 

    M. Ouberai, F. El Garch, A. Bussiere, M. Riou, D. Alsteens, L. Lins, I. Baussanne, Y. F. Dufrene, R. Brasseur, J.-L. Decout, M.-P. Mingeot-Leclercq.

    BBA - Biomembranes 2011, 1808, 1716–1727.

  • Article • An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors. 

    B.-L. Renard, B. Boucherle, B. Maurin, M.-C. Molina, C. Norez, F. Becq, J.-L. Decout.

    Eur. J. Med. Chem. 2011, 46, 1935-1941.

  • Article • Flavonoids as anticancer agents: Recent Progress and state of the art 

    E. Genoux, E. Nicolle, A. Boumendjel

    Curr. Org. Chem. 2011, 15, 2608-2615.

  • Article • Targeting the multidrug resistance-conferring ABCG2 transporter with flavonoidic inhibitors: in vitro optimization and in vivo validation 

    A. Boumendjel, S. Macalou, G. Valdameri, A. Pozza, C. Gauthier, O. Arnaud, E. Nicolle, S. Magnard, P. Falson, R. Terreux, P.-A. Carrupt, L. Payen, A. Di Pietro

    Curr. Med. Chem. 2011, 18, 3387-3401.

  • Article • Flavonoids as promising lead compounds in type 2 diabetes mellitus: molecules of interest and structure-activity relationship 

    E. Nicolle, F. Souard, P. Faure, A. Boumendjel

    Curr. Med. Chem. 2011,18, 2661-2672.

  • Patent • Anti-angiogenic compounds, pharmaceutical compositions containing same, and use thereof 

    J.J. Feige, A. Castan, D. Quelard, M. Demeunynck, J.F. Constant, C. Barette

    2011 • CNRS

  • Patent • Preparation of novel azacoumarin derivs. as MDR pump inhibitors useful as antimicrobial agents and as potentiators of the antimicrobial agents 

    A. Doleans-Jordheim, J. Freney, C. Dumontet, A. Boumendjel, J.-B. Veron, Y.-S. Wong

    2011 • UJF, CNRS, UCBL1, Hospices Civils de Lyon

  • Patent • Protocoagulant pour hémophile  

    A. Thomas & B. Polack

    2011 • 

  • Book • Chemogenomics and chemical genetics 

    Some principles of diversity-oriented synthesis

    Yung-Sing Wong

    2011 • 113-130, Springer

  • Thesis • Pharmacochimie des aurones pour la modulation d'enzymes 

    R. Haudecoeur

    2011 • 

  • Article • Neutral Coatings for the Study of Polycation/Multicharged Anion Interactions by Capillary Electrophoresis: Application to Dendrigraft Poly-L-lysines with Negatively Multicharged Molecules [Full paper ]

    T. Zou, F. Oukacine, T. Le Saux, H. Cottet

    Anal. Chem. 2010, 82, 7362-7368.

  • Article • Rationally Designed Aptamer-Based Fluorescence Polarization Sensor Dedicated to the Small Target Analysis 

    S. Perrier, C. Ravelet, V. Guieu, J. Fize, B. Roy, C. Perigaud, E. Peyrin.

    Biosens. Bioelectron. 2010, 25, 1652-1657.

  • Article • Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. 

    I. Baussanne, A. Bussiere, S. Halder, C. Ganem-Elbaz, M. Ouberai, M. Riou, J.-M. Paris, E. Ennifar, M.-P. Mingeot-Leclercq, J.-L. Decout.

    J. Med. Chem. 2010, 53, 119-127.

  • Article • Identification of a novel water soluble activator of wild-type and F508del CFTR: GPact-11a. 

    J. Bertrand, B. Boucherle, A. Billet, P. Melin-Heschel, L. Dannhoffer, C. Vandebrouck, C. Jayle, C. Routaboul, M.-C. Molina, J.-L. Decout, F. Becq, C. Norez.

    Eur. Respir. J. 2010, 36, 311-322.

  • Article • Multiplexed detection of small analytes by structure-switching aptamer-based capillary electrophoresis 

    Z. Zhu, C. Ravelet, S. Perrier, V. Guieu, B. Roy, C. Perigaud, E. Peyrin.

    Anal. Chem. 2010, 82, 4613-4620.

  • Article • 1-Azaaurones derived from the naturally occurring aurons as potential antimalarial drugs. 

    F. Souard, S. Okombi, C. Beney, S. Chevalley, A. Valentin, A. Boumendjel.

    Bioorg. Med. Chem. 2010, 18, 5724-5731.

  • Article • Hypervalent iodine(III)-mediated tandem oxidative reactions: application for the synthesis of bioactive polyspirocyclohexa-2,5-dienones. 

    M. Traoré, S. Ahmed-Ali, M. Peuchmaur, Y.-S. Wong.

    Tetrahedron 2010, 66, 5863-5872.

  • Article • Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds. 

    D. Maubon, A. Bougdour, Y.-S. Wong, M.-P. Brenier-Pinchart, A. Curt, M.-A. Hakimi, H. Pelloux.

    Antimicrob. Agents Chemother. 2010, 54, 4843-4850.

  • Article • Swift and efficient synthesis of 4-phenylquinazolines: involvement of N-heterocyclic carbene in the key cyclization step 

    J. Debray, J.-M. Leveque, C. Philouze, M. Draye, M. Demeunynck

    J. Org. Chem., 2010, 75, 2092-95

  • Article • Montmorillonite K-10 catalyzed cyclization of N-ethoxycarbonyl-N’-arylguanidines: access to pyrimido[4,5-c]carbazole and pyrimido[5,4-b]indole derivatives 

    J. Debray, W. Zeghida, B. Baldeyrou, C. Mahieu, A. Lansiaux, M. Demeunynck

    Bioorg. Med. Chem. Lett., 2010, 20, 4244-4247

  • Patent • Nouveaux dérives hétérocycliques, pour leur activité antivirale, en particulier pour le traitement du VHC 

    A. Boumendjel, R. Haudecoeur, H. Ahmed-Belkacem, J.-M. Pawlotsky, R. Brillet, C. Belle

    2010 • UJF, CNRS

  • Patent • Derives de glucosamine et leur utilisation comme agents antibacteriens. Brevet français déposé le 9/11/2010 (Université de Grenoble/CNRS). 

    J.-L. Decout, I. Das, J. Desire, I. Baussanne, M.-P. Mingeot-Leclercq.

    2010 • Université Joseph Fourier/CNRS

  • Book • Chiral recognition in separation methods. Mechanisms and applications 

    Enantioselective properties of nucleic acid aptamer molecular recognition elements

    E. Peyrin

    2010 • 275-288, Springer

  • Article • Solid-phase synthesis of isocoumarins: a traceless halocyclization approach. 

    Peuchmaur M., Lisowski V., Gandreuil C., Maillard L. T., Martinez J., Hernandez J.-F.

    J. Org. Chem. 2009, 74, 4158-4165.

  • Article • 3D Solvatochromic analysis of molecular interaction forces between flavonoid derivatives and P glycoprotein mediated multidrug resistance 

    J. Boccard, E. Nicolle, A. Di Pietro, J. Boccard, S. Rudaz, A. Boumendjel, P.-A. Carrupt

    Eur. J. Pharm. Sci. 2009, 36, 254-264.

  • Article • Colloidal systems made of biotransesterified alpha, beta, and gamma cyclodextrins grafted with C10 alkyl chains 

    A. Geze, L. Choisnard, J-L. Putaux, D. Wouessidjewe

    Materials science and engineering, 2009 ,C29,458-462

  • Article • QSAR analysis and molecular modeling of ABCG2-specific inhibitors 

    A. Boumendjel, E. Nicolle, S. Macalou, E. Genoux, A. Ahmed-Belkacem, P.-A. Carrupt, A. Di Pietro.

    Adv. Drug. Deliver. Rev. 61, 34-46.

  • Article • Chalcones derivatives acting as cell cycle blockers: Potential anticancer drugs 

    A. Boumendjel, X. Ronot, J. Boutonnat

    Curr. Drug. Targets, 2009, 10, 363-371.

  • Article • Chiral ligand-exchange chromatography of amino acids using porous graphitic carbon coated with a dinaphthyl derivative of neamine. 

    M. Zaher, C. Ravelet, I. Baussanne, A. Ravel, C. Grosset, J.-L Decout, E. Peyrin.

    Anal. Bioanal. Chem. 2009, 393, 655-660.

  • Article • Aptamer-Modified Micellar Electrokinetic Chromatography for the Enantioseparation of Nucleotides. 

    J. Ruta, S. Perrier, C. Ravelet, B. Roy, C. Perigaud, E. Peyrin.

    Anal. Chem. 2009, 81, 1169-1176.

  • Article • Enantioseparation by micellar electrokinetic chromatography using a ligand exchange-based chiral pseudostationary phase 

    M. Zaher, C. Ravelet, C. Vanhaverbeke, I. Baussanne, S. Perrier, J. Fize, J.-L. Decout, E. Peyrin

    Electrophoresis, 2009, 30, 2869-2873

  • Article • Nucleic acid aptamer molecular recognition principles and application in liquid chromatography and capillary electrophoresis 

    E. Peyrin

    J. Sep. Sci. 2009, 32, 1531-1536.

  • Article • Investigation of a new 1,3-diarylpropenone as a potential antimitotic agent targeting bladder carcinoma 

    V. Martel-Frachet, J. Areguian, M. Blanc, B. Touquet, A. Lamarca, X. Ronot, A.Boumendjel.

    Anti-Cancer Drugs

  • Article • Antioxidant and free radical-scavenging properties of three flavonoids isolated from the leaves of Rhamnus alaternus L.(Rhamnaceae):A structure-activity relationship study 

    R.Ben Ammar, W.Bhouri, M.Ben Sghaier, J.Boubaker, I.Skandrani, A.Neffati, I.Bouhlel, S.Kilani, AM.Mariotte, L.Chekir-Ghedira, MG.Dijoux-Franca, K.Ghedira

    Food Chemistry. 2009, 116, 258-264

  • Article • Breast Cancer Resistance Protein (BCRP, ABCG2): New Inhibitors and QSAR Studies by 3D Solvatochromic Analysis 

    E. Nicolle, J. Boccard, D. Guilet, M.-G. Dijoux-franca, E. Zelefac, S. Macalou, J. Schmidt, P.-A. Carript, A. Di Pietro, A. Boumendjel

    Eur. J. Pharm. Sci. 2009, 38, 39-46

  • Article • Noncompetitive fluorescence polarization aptamer-based assay for small molecule detection 

    J. Ruta, S. Perrier, C. Ravelet, J. Fize, E. Peyrin.

    Anal. Chem. 2009, 81, 7468-7473.

  • Article • Determination of cocaine in human plasma by selective solid-phase extraction using aptamer-based sorbent 

    B. Madru, F. Hugon, E. Peyrin, V. Pichon

    Anal. Chem. 2009, 81, 7081-7086.

  • Article • Polycationic amphiphilic cyclodextrins for gene delivery: synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity and gene expression 

    A. Diaz-Moscoso, L. Le Gourriérec, M. Gomez-Garcia, J.M. Benito, P. Balbuena, F. Ortega-Caballero, N. Guilloteau, C. Di Giorgio, P. Vierling, J. Defaye, C. Ortiz Mellet, J.M. Garcia Fernandez

    Chem. Eur. J., 2009, 15, 12871-12888

  • Article • Synthesis and transfection properties of a series of lipidic neamine derivatives. 

    T. Le Gall, I. Baussanne, S. Halder, N. Carmoy, T. Montier, P. Lehn, J.-L. Decout.

    Bioconjugate Chem. 2009, 20, 2032-2046.

  • Article • A. Boumendjel, M. Blanc, G. Williamson, D. Barron. An efficient synthesis of flavanone glucuronides. 

    A. Boumendjel, M. Blanc, G. Williamson, D. Barron.

    J. Agric. Food Chem. 2009, 57, 7264-7267.

  • Article • A new chalcone derivative as a potential agent for treatment of glioblastoma. 

    A. Boumendjel, A. Florin, P. Champelovier, V. Peyrot, D. Allegro, D. Muhammad, F. Souard, M. Derouazi, B. Toussaint, J. Boutonnat

    BMC Cancer, 2009, 9, 242-250.

  • Patent • Peptides cycliques à activité antiparasitaire 

    Y.-S. Wong, A. Hakimi, A. Bougdour, H. Pelloux, D. Maubon.

    2009 • Floralis/UJF INSERM CNRS

  • Book • Aptamers in bioanalysis 

    Aptamers for separation of enantiomers

    C. Ravelet, E. Peyrin

    2009 • Wiley

  • Book • Functional Nucleic Acids for Analytical Applications 

    Aptamers in affinity separations

    C. Ravelet, E. Peyrin

    2009 • Springer

  • Book • ABC Proteins and Multidrug Resistance 

    Reversal agents of multidrug resistance mediated by MRPS

    A. Boumendjel, A. Florin, J. Boutonnat

    2009 • 261-288, Wiley & Sons, Inc. - New Jersey, USA

  • Book • ABC Proteins and Multidrug Resistance 

    Reversal agents for breast cancer resistance protein (BCRP)-mediated multidrug resistance

    J. Boutonnat, A. Florin, A. Boumendjel

    2009 • 289-313, Wiley & Sons, Inc. - New Jersey, USA

  • Book • Science of Synthesis 

    1,3-Dienes: Synthesis from Arenes and Polyenes

    Y.-S. Wong

    2009 • 589-635,

  • Oral Comm • Pharmacological characterization of a novel water-soluble activator of F508del-CFTR 

    J. Bertrand, B. Boucherle, L. Dannhoffer, P. Melin, C. Routaboul, J. L. Décout, F. Becq, C. Norez

  • Article • Antimitotic and antiproliferative activities of chalcones: Forward structure-activity relationship 

    A. Boumendjel, E. Nicolle, P.-A. Carrupt, J. Boccard, M. Blanc, A. Geze, L. Choisnard, D. Wouessidgewe, C. Dumontet

    J. Med. Chem. 2008, 51, 2307-2310.

  • Article • Covalently bonded DNA aptamer chiral stationary phase for the chromatographic resolution of adenosine. 

    J. Ruta, C. Ravelet, J. Désiré, J.-L. Décout, E. Peyrin.

    Anal. Bioanal. Chem. 2008, 390, 1051-1057.

  • Article • Copper(II) complexes of lipophilic aminoglycoside derivatives for the amino acid enantiomeric separation by ligand-exchange liquid chromatography. [Full paper ]

    M. Zaher, I. Baussanne, C. Ravelet, S. Halder, M. Haroun, J. Fize, J.-L. Decout, E. Peyrin.

    J Chromatogr A. 2008, 1185, 291-295.

  • Article • Characterisation of complex amphiphilic cyclodextrin mixtures by high-performance liquid chromatography and mass spectrometry. 

    F. Kieken, C. West, K. Keddadouche, C. Elfakir, L. Choisnard, A. Gèze, D. Wouessidjewe

    J. Chrom. A, 2008, 1189, 385-391.

  • Article • Rational design of cationic cyclooligosaccharides as efficient gene delivery systems 

    A. Diaz-Moscoso, P. Balbuena, M. Gomez-Garcia, C. Ortiz Mellet, J.M. Benito, L. Le Gourrierec, C. Di Giorgio, P. Vierling, A. Mazzaglia, N. Micali, J. Defaye, J.M. Garcia Fernandez

    Chem. Commun., 2008, 2001-2003.

  • Article • Flavonoids as RTK inhibitors and potential anticancer agents. 

    F. Teillet, A. Boumendjel, J. Boutonnat and X. Ronot

    Med. Res. Rev. 2008,28, 715-745

  • Article • The effect of flavonoid derivatives on doxorubicin transport and metabolism 

    R. Václavíková, E. Kondrová, M. Ehrlichová, A. Boumendjel, J. Kovář, P. Stopka, P. Souček and I. Gut

    Bioorg. Med. Chem. 2008, 16, 2034-2042

  • Article • Biotransformation of anthracene by Tetrahymena pyriformis and selected fungi and toxicity of the biotransformation products 

    P. Guiraud, J-L. Bonnet, A. Boumendjel, M. Kadri, M. Dusser, J. Bohatier and R. Steiman

    Ecotox. Environ. Safety, 2008, 69, 296-305

  • Article • Competitive affinity capillary electrophoresis assay based on a hybrid pre-incubation/on-capillary mixing format using an enantioselective aptamer as affinity ligand. 

    J. Ruta, C. Ravelet, I. Baussanne, J. Fize, J.-L. Decout, E. Peyrin.

    J. Sep.Sci. 2008, 31, 2239-2243

  • Article • Anti-retroviral and cytostatic activity of 2',3'-dideoxyribonucleotide 3'-disulfides. 

    B. Gerland, J. Desire, J. Balzarini, J.-L. Decout.

    Bioorg. Med. Chem. 2008, 16, 6824-6831.

  • Article • The PAMPA technique as a HTS tool for partition coefficients determination in different solvent/water systems. 

    G. Ottaviani, S. Martel, C. Escalata, E. Nicolle, P.-A. Carrupt.

    Eur. J. Pharm. Sci. 2008, 35, 68-75.

  • Article • Unusual addition of amines to C-2 of vinyl sulfone-modified-β-D-pent-2-enofuranosyl carbohydrates: synthesis of a new class of β-anomeric D-arabino-2,3-Dideoxy-2-aminofuranosides. 

    I. Das, C. G. Suresh, J.-L. Decout, T. Pathak.

    Carbohydrate Res. 2008, 343, 1287-1296.

  • Article • Diastereodivergence and appendage diversity in the multicomponent synthesis of aryl-pyrrolo-tetrahydrocarbazoles. 

    D. Royer, Y.-S. Wong, S. Ple, A. Chiaroni, K. Diker, J. Lévy.

    Tetrahedron 2008, 64, 9607-9618.

  • Article • Expanding the chemical space: Diversity-Oriented Synthesis. 

    M. Peuchmaur, Y.-S. Wong.

    Comb. Chem. High Throughput Screen. 2008, 11, 587-601.

  • Article • Enhanced antimalarial activity of novel synthetic aculeatin derivatives. 

    M. Peuchmaur, N. Saïdani, C. Botte, E. Marechal, H. Vial, Y.-S. Wong.

    J. Med. Chem. 2008, 51, 4870-4873.

  • Article • New Components Including Cyclopeptides from Barks of Christiana africana DC.(Tiliaceae) 

    S.Michalet, L.Payen-Fattaccioli, C.Beney, P.Cegiela, C.Bayet, G.Cartier, D.Noungoue-Tchamo, E.Tsamo, AM.Mariotte, MG.Dijoux-Franca

    Helv.Chim.Acta.2008, 91, 1106-1117.

  • Article • N.Hayder, I.Bouhlel, I.Skandrani, M.Kadri, R.Steinman, P.Guiraud, AM.Mariotte, K.Ghedira, MG Dijoux-Franca, L.Chekir-Ghedira 

    In vitro antioxidant and antigenotoxic potentials of myricetin-3-O-galactoside and myricetin-3-O-rhamnoside from Myrtus communis:modulation of expression of genes involved in cell defence system using cDNA microarray

    Toxicol in Vitro 2008,22, 567-581

  • Article • Tailoring beta-cyclodextrin for DNA complexation and delivery by homogeneous functionalization at the secondary face 

    F. Ortega-Caballero, C. Ortiz Mellet, L. Le Gourrierec, N. Guilloteau, C. Di Giorgio, P. Vierling, J. Defaye, J.M. Garcia Fernandez

    Org. Lett., 2008, 10, 5143-5146

  • Article • Les phénomènes de résistance aux antibiotiques liés aux pompes à efflux: exemple de Staphylococcus aureus 

    A. Doléans-Jordheim, S. Michalet, E. Bergeron, S. Boisset, F. Souard, C. Dumontet, M.-G. Dijoux-Franca, J. Freney

    Ann. Biol. Clin. 2008, 66(5), 499-508

  • Article • Identification of chemical inhibitors of protein-kinase CK2 subunit interaction. 

    B. Laudet, V. Moucadel, R. Prudent, O. Filhol, Y.-S. Wong, D. Royer, C. Cochet.

    Mol. Cell. Biochem. 2008, 316, 63-69.

  • Article • Antimutagenic, antigenotoxic and antioxidant activities of Acacia salicina extracts (ASE) and modulation of cell gene expression by H2O2 and ASE treatment. 

    I.BOUHLEL, K. VALENTI, S. KILANI, I. SKANDRANI, M. BEN SGHAIER, AM MARIOTTE, MG DIJOUX-FRANCA, K. GHEDIRA, I.HININGER-FAVIER, F.LAPORTE, L.CHEKIR-GHEDIRA

    Toxocology in Vitro 2008, 22, 1264-1272

  • Article • Targeted beta-cyclodextrin-based gene delivery systems: physicochemical and transfection studies 

    N. Guilloteau, L. Legourrierec, A. Diaz-Moscoso, C. Ortiz Mellet, J.M. Benito, C. Di Giorgio, P. Vierling, J. Defaye, J.M. Garcia Fernandez

    Human Gene Therapy, 2008, 19, 1157.

  • Patent • Nouveaux dérivés de la néamine, méthode de préparation et propriétés antibiotiques. 

    J.-L. Decout, I. Baussanne, J. Desire, J.-M. Paris.

    2008 • Université Joseph Fourier/CNRS

  • Thesis • Synthèse et évaluation de modulateurs de la protéine CFTR. 

    Benjamin Boucherle

    2008 • Université Joseph Fourier

  • Oral Comm • Activation of chloride secretion in human airway epithelial cells by a new pyrrolo[2,3-b]pyrazine 

    L. Dannhoffer, P. Melin, C. Faveau, B. Boucherle, C. Jayle, P. Corbi, Y. Mettey, J. L. Décout, F. Becq

  • Article • Chiral resolution of histidine using an anti-D-histidine L-RNA aptamer microbore column 

    J. Ruta, C. Grosset, C. Ravelet, J. Fize, A. Villet, A. Ravel, E. Peyrin

    J. Chromatogr. B 2007, 845, 186-190.

  • Article • Study of antimutagenic and antioxydant activities of gallic acid and 1,2,3,4,6-pentagalloylglucose from Pistacia lentiscus. Confirmation by microarray expression profiling 

    A. Abdelwahed, I. Bouhled, I. Skandrani, K. Valenti, M. Kadri, P. Guiraud, R. Steiman, A.-M. Mariotte, K. Ghedira, F. Laporte, M.-G. Dijoux-Franca, L. Chekir-Ghedira

    Chem. Biol. Int. 2007, 165, 1-13.

  • Article • 2-Arylidenedihydroindole-3-ones: Design, synthesis, and biological activity on bladder carcinoma cell lines. 

    B. Gerby, A. Boumendjel, M. Blanc, P. P. Bringuier, P. Champelovier, A. Fortune, X. Ronot, J. Boutonnat.

    Bioorg. Med. Chem. Lett. 2007, 17, 208-213.

  • Article • Glycochimie et thérapeutique: Les cyclodextrines en Pharmacie, perpectives pour le ciblage d'actifs thérapeutiques et le contrôle d'interactions membranaires 

    J. Defaye, J.M. Garcia Fernandez, C. Ortiz Mellet

    Ann. Pharm. Fr. 2007, 65, 33-49.

  • Article • Poudres, granulés et comprimés dans Pharmacie Galénique : Formulation et technologie Pharmaceutique 

    V. Busignies, D. Chulia, L. Choisnard, R. de Challemaison, A. Geze, S. Stainmesse, J. Siepmann, P. Tchoreloff, M. Viana, P. Wehrlé, D. Wouessidjewe,

    Editions Maloine 2007, Chapitre 2, 1-45.

  • Article • Formes galéniques en développement dans Pharmacie Galénique : Formulation et technologie Pharmaceutique 

    S. Begu, A. Bochot, L. Choisnard, P. Couvreur, D. Duchene, F. Edwards, E. Fattal, A. Geze, G. Ponchel, V. Preat, C. Tourne-Petaeille, D. Wouessidjewe

    Editions Maloine. 2007, Chapitre 8, 1-36.

  • Article • N-Caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors 

    S.Michalet, G.Cartier, B.David, A-M.Mariotte, M-G.Dijoux-Franca, GW.Kaatz, M.Stavri, S Gibbons

    Bioorg. Med. Chem. Lett 2007, 17, 1755-1758.

  • Article • Aptamer-based enantioselective competitive binding assay for the trace enantiomer detection. 

    J. Ruta, C. Ravelet, I. Baussanne, J.-L. Decout, E. Peyrin.

    Anal. Chem. 2007, 79, 4716-4719.

  • Article • Direct preparation of nucleoside vinyl disulfides from 2-(trimethylsilyl)ethyl sulfides, an access to vinylthiols. 

    B. Gerland, J. Desire, M. Lepoivre, J.-L. Decout

    Org. Lett. 9, 2007, 3021-3023.

  • Article • A structure-based approach for targeting the HIV-1 genomic RNA dimerization initiation site. 

    E. Ennifar, J.-C. Paillart, S. Bernacchi, P. Walter, P. Pale, J.-L. Decout, R. Marquet, P. Dumas.

    Biochimie 2007, 89, 1195-1203

  • Article • Discovery of alpha-aminoazaheterocycle-methylglyoxal adducts as a new class of high affinity inhibitors of CFTR chloride channels. 

    C. Routaboul, C. Norez, P. Melin, M.-C. Molina, B. Boucherle, F. Bossard, S. Noel, R. Robert, C. Gauthier, F. Becq, J.-L. Decout.

    J. Pharmacol. Exp. Ther. 2007, 322, 1023-1035.

  • Article • Mechanism of RNA cleavage catalyzed by sequence specific polyamide nucleic acid-neamine conjugate. 

    B. Chaubey, S. Tripathi, J. Desire, I. Baussanne, J.-L. Decout, V. Pandey.

    Oligonucleotides 2007, 17, 302-313.

  • Article • Diastereodivergent Strategies for the Synthesis of Homochiral Aculeatins. 

    M. Peuchmaur, Y.-S. Wong.

    J. Org. Chem. 2007, 72, 5374-5379.

  • Article • Miscellaneous nanoaggregates made of beta-CD esters synthesised by an enzymatic pathway 

    L. Choisnard, A. Geze, B.G.J. Yaméogo, J-L. Putaux, D. Wouessidjewe

    Int. J. Pharm. 2007, 344, 26-32.

  • Article • Biodistribution of intravenously administered amphiphilic beta-cyclodxetrin nanospheres 

    A. Geze, L. Tieu Chau, L. Choisnard, J.-P. Mathieu, D. Marti-Batlle, L. Riou, J.-P. Putaux, D. Wouessidjewe

    Int. J. Pharm. 2007, 344, 135-142.

  • Article • Studies towards the synthesis of aculeatin C. 

    M. Peuchmaur, Y.-S. Wong.

    Synlett 2007, 18, 2902-2906.

  • Article • Transcriptional response of genes involved in cell defense system in human cells stressed by H2O2 and pre-treated with (Tunisian) Rhamnus alaternus extracts: Combination with polyphenolic compounds and classic in vitro assays. 

    R.Ben Ammar, I.Bouhlel, K.Valenti, M.Ben Sghaier, S.Kilani, A-M.Mariotte, M-G.Dijoux-Franca, F.Laporte, K.Ghedira, L.Chekir-Ghedira.

    Chem.Biol.Interact 2007,168,171-183

  • Article • Use of p-hydroxycinnamic acid derivatives in cosmetic or dermatological compositions. 

    S.Okombi, D.Rival, A.Boumendjel, A-M.Mariotte, E. Perrier.

    Brit. UK Pat. Appl. 2007, 66pp. CODEN: BAXXDU GB 2431876 A 20070509

  • Article • Preparation of new chalcone derivatives with antimitotic activity. 

    A.Boumendjel, Ch.Dumontet, M.Blanc, A-M.Mariotte.

    Fr. Demande 2007,33pp. CODEN: FRXXBL FR 2896245 A1 20070720

  • Article • Acridone derivatives: design, synthesis, and inhibition of breast cancer resistance protein ABCG2. 

    A. Boumendjel, S. Macalou, H.Ahmed-Belkacem, M. Blanc, A. Di Pietro.

    Bioorg. Med. Chem. 2007, 15, 2892-2897.

  • Patent • Chiral selectors for separating enantiomers of a compound. 

    E. Peyrin, J.-L. Décout, C. Ravelet, I. Baussanne.

    2007 • Université de Grenoble I/CNRS

  • Patent • Nouveaux composes polyspiranniques, leur application dans le traitement du paludisme ou de la toxoplasmose et leur procede de preparation. 

    M. Peuchmaur, Y.-S. Wong, N. Saidani, C. Botte, H. Vial, E. Marechal.

    2007 • Universite Grenoble I, CNRS.

  • Book • Chemogenomique, des petites molécules pour explorer le vivant 

    Quelques principes sur la Synthese Orientee vers la Diversite

    Y.-S. Wong.

    2007 • 121-139, - Grenoble

  • Book • Pharmacie Galénique : Formulation et technologie Pharmaceutique 

    poudres, granulés et comprimés dans Pharmacie Galénique

    V. Busignies, D. Chulia, L. Choisnard, R. de Challemaison, A. Gèze, S. Stainmesse, J. Siepmann, P. Tchoreloff, M. Viana, P. Wehrlé, D. Wouessidjewe

    2007 • 1-44, Maloine - Paris

  • Book • Pharmacie Galenique : Formulation et technologie pharmaceutique 

    Formes galéniques en développement dans Pharmacie Galénique

    S. Begu, A. Bochot, L. Choisnard, P. Couvreur, D. Duchene, F. Edwards, E. Fattal, A. Geze, G. Ponchel, V. Preat, C. Tourné-Peteilh, D. Wouessidjewe

    2007 • 250-289, Maloine - Paris

  • Thesis • Mirabilis jalapa L. (Nyctaginaceae) et Modulation de la Résistance Bactérienne aux Antibiotiques. 

    Serge MICHALET

    2007 • UJF

  • Thesis • Synthèse de composés polyspiranniques par oxydation phenolique. Synthèse totale des aculéatines et d'analogues antipaludiques 

    M. Peuchmaur

    2007 • Université Joseph Fourier

  • Thesis • Phases stationnaires chirales à base de teicoplanine et d'aminoglycosides pour la séparation d'énantiomères d'acides aminés 

    Mohamed Haroun

    2007 • Thèse soutenue en 2007

  • Article • Discovery of Benzylidenebenzofuran-3(2H)-one (Aurones) as Potent Inhibitors of Human Tyrosinase 

    S. Okombi, D. Rival, A.-M. Mariotte, E. Perrier, A. Boumendjel

    J. Med. Chem. 2006, 49, 329-333.

  • Article • Reversal of the enantiomeric elution order of some aromatic amino acids using reversed-phase chromatographic supports coated with the teicoplanin chiral selector 

    M. Haroun, C. Ravelet, C. Grosset, A. Ravel, A. Villet, E. Peyrin

    Talanta 2006, 68, 1032-1036.

  • Article • Towards a better understanding of the basis of molecular mimicry of polysaccharide antigens by peptides : The example of Shigella flexneri 5a 

    Marie-Jeanne Clement, Antoine Fortune, Armelle Phalipon, Veronique Marcel-Peyre, Catherine Simenel, Anne Imberty, Muriel Delepierre, and Laurence A. Mulard

    J. Biol. Chem., 2006, 281, 2317-2332

  • Article • Inhibitors of cancer cell multidrug resistance mediated by Breast Cancer Resistance Protein (BCRP/ABCG2) 

    A. A. Belkacem, A. Pozza, S. Macalou, J. M. Perez-Victoria, A. Boumendjel, A. Di Pietro

    Anti-Cancer Drugs, 2006, 17, 239-244.

  • Article • Analogues of N-cinnamoylphenalkylamides: potent inhibitors of human-melanocyte tyrosinase 

    S. Okombi, D. Rival, A-M. Mariotte, E. Perrier, A. Boumendjel

    Bioorg. Med. Chem. Lett. 2006, 16, 2252-2255.

  • Article • New Development in the Asymmetric Synthesis of Heterocyclic Natural Products. 

    I. Baussanne, B. Dudot, J. Perard-Viret, L. Planas,J. Royer.

    Arkivoc, 2006, Part VII, 57-66

  • Article • Modulation of paclitaxel transport by flavonoide derivatives in human breast cancer cells. Is there a Correlation Between Binding Affinity to NBD of P-gp and Modulation of Transport? 

    R. Vaclavikova, A. Boumendjel, M. Ehrlichova, J. Kovar, I. Gut

    Bioorg. Med. Chem. 2006, 14, 4519-4525.

  • Article • Enantiomeric separation using a L-RNA aptamer as chiral additive in partial-filling capillary electrophoresis. 

    J. Ruta, C. Ravelet, C. Grosset, J. Fize, A. Ravel, A. Villet, E. Peyrin.

    Anal. Chem. 2006, 78, 3032-3039.

  • Article • Recent developments in the HPLC enantiomeric separation using chiral selectors identified by a combinatorial strategy 

    C. Ravelet, E. Peyrin

    J. Sep. Sci. 2006, 29, 1322-1331.

  • Article • Aptamers as ligands for affinity chromatography and capillary electrophoresis applications 

    E. Peyrin

    The Aptamer Handbook. The fonctional oligonucleotides and their applications. Editor: Sven Klussmann, Wiley-VCH, 2006.

  • Article • Liquid chromatography, electrochromatography and capillary electrophoresis applications of DNA and RNA aptamers 

    C. Ravelet, C. Grosset, E. Peyrin

    J. Chromatogr. A 2006, 1117, 1-10.

  • Article • Sequence-specific nucleic acid damage induced by “enzyme activable” peptide nucleic acid conjugates 

    P. Simon, J.-L. Decout, M. Fontecave

    Angew. Chem. Int. Ed. 2006,45, 6859-6861.

  • Article • Glyconanocavities: Cyclodextrins and beyond 

    J.M. Garcia Fernandez, C. Ortiz Mellet, J. Defaye

    J. Incl. Phenom. Macrocycl. Chem. 2006, 56, 149-159.

  • Article • Nanoparticles of b-cyclodextrin esters obtained by self-assembling of biotransesterified b-cyclodextrin 

    L. Choisnard, A. Geze, J.L. Putaux, Y.S. Wong, D. Wouessidjewe

    Biomacromolecules 2006, 7, 515-520.

  • Article • Experimental design optimization for screening relvant free phenolic acids from various preparations used in Burkina Faso folk medicine 

    M. Kienbrebego, L. Choisnard, C. E. Lamien, A. Meda, D. Wouessidjewe, O. Nacoulma

    Afr. J. Trad. Comp. Alt. Med. 2006, 3, 115-128.

  • Article • Two new xanthone diglycosides from Swertia longifolia Boiss. 

    H. Hajimehdipoor, M.-G. Dijoux-Franca, A.-M. Mariotte, Y. Amanzadeh, S-E. Sadat-Ebrahimi, M. Gazi-Khansari

    Natural Product Research,Part A:Structure and Synthesis 2006, 20, 1251-1257.

  • Patent • Process for the preparation of nucleoside disulfides and thiosulfinates 

    J.-L. Decout, B. Gerland, J. Desire

    2006 • Université de Grenoble I / CNRS

  • Patent • Nouveaux dérivés de chalcones à activité antimitotique. 

    A. Boumendjel, M. Blanc, A.-M. Mariotte, C. Dumontet.

    2006 • Université Claude Bernard - Lyon I, Université Joseph Fourier - Grenoble I INSERM CNRS

  • Patent • Preparation of nanosphere amphiphilic cyclodextrin derivatives as biological transporters 

    J. Defaye, P. Balbuena, J.M. Benito, A. Diaz Moscoso, C. Di Giorgio, J.M. Garcia Fernandez, A. Geze, M. Gomez Garcia, C. Ortiz Mellet, P. Vierling, D. Wouessidjewe

    2006 • CNRS

  • Patent • Preparation of thionucleosides as antiviral and antitumor agents 

    J.-L. Decout, B. Gerland, J. Desire, M. Lepoivre, J. Balzarini.

    2006 • Université de Grenoble I / CNRS

  • Book • La cytométrie en flux 

    Fluorochromes

    A. Boumendjel, D. Grunwald,E. Nicolle, X. Ronot

    2006 • 47-58, Lavoisier - Paris

  • Thesis • Techniques de Modélisations Moléculaires Appliquées à l'Etude et à l'Optimisation de Molécules Immunogènes et de Modulateurs de la Chimiorésistance. 

    Antoine Fortuné

    2006 • Université Joseph Fourrier (Grenoble 1)

  • Thesis • Synthèse de thionucléosides antiviraux et/ou antiprolifératifs 

    Beatrice Gerland

    2006 • Université Joseph Fourier

  • Article • Modulation of multi-drug-resistance (MDR) in Staphylococcus aureus by Osha (Ligusticum porteri L., Apiaceae) essential oil compounds 

    P. Cegiela-Carlioz, J-M. Bessiere, B. David, A-M. Mariotte, S. Gibbons, M-G. Dijoux-Franca

    Flav. Fragr. J. 2005, 20, 671-675.

  • Article • Chiral stationary phase based on a biostable L-RNA aptamer 

    A. Brumbt,C. Ravelet,C. Grosset,A. Ravel,A. Villet, E. Peyrin

    Anal. Chem. 2005, 77, 1993-1998.

  • Article • Thermodynamic origin of the chiral recognition of tryptophan on teicoplanin and teicoplanin aglycone stationary phases 

    M. Haroun,C. Ravelet,A. Ravel,C. Grosset,A. Villet, E. Peyrin

    J. Sep. Sci. 2005, 28, 409-420.

  • Article • Semi-permeable membrane device efficiency for sampling free soluble fraction of polycyclic aromatic hydrocarbons 

    C. Miege,C. Ravelet,J. P. Croue,J. Garric

    Anal. Chim. Acta 2005, 536, 259-266.

  • Article • DNA detection through signal amplification using NADH:Flavin Oxidoreductase and oligonucleotide-flavin conjugates as cofactors 

    P. Simon, C. Dueymes, M. Fontecave, J.-L. Decout

    Angew. Chem. Int. Ed. 2005, 44, 2764-2767.

  • Article • A new isoflavone from Genista saharae (Fabaceae) 

    R. Mekkiou, H. Touahar, MG. Dijoux-Franca, AM. Mariotte, S. Benayache, F. Benayache

    Biochem. Syst. Ecol. 2005, 33, 635-638.

  • Article • A L-RNA aptamer chiral stationary phase for the resolution of target and related compounds 

    C. Ravelet, R. Boulkedid, A. Ravel, C. Grosset, A. Villet, J. Fize, E. Peyrin

    J. Chromatogr. A 2005, 1076, 62-70.

  • Article • Probing secondary carbohydrate-protein interactions with highly dense cyclodextrin-centered heteroglycoclusters: The heterocluster effect 

    M. Gomez-Garcia, J.M. Benito, D. Rodriguez-Lucena, J.-X. Yu, K. Chmurski, C. Ortiz Mellet, R. Gutierrez Gallego, A. Maestre, J. Defaye, J.M. Garcia Fernandez

    J. Am. Chem. Soc. 2005, 127, 7970-7971.

  • Article • How precisely do Semi-Permeable Membrane Devices (SPMD) measure the bioavailability of Polycyclic Aromatic Hydrocarbons to Daphnia magna ? 

    C. Gourlay, C. Miege, A. Noir, C. Ravelet, J. Garric, J. M. Mouchel

    Chemosphere 2005, 61, 1734-1739.

  • Article • Anticancer Multidrug Resistance Mediated by MRP1: Recent Advances in the Discovery of Reversal Agents 

    A. Boumendjel.; G. Conseil.; H. Baubichon-Cortay.; and A. Di Pietro

    Med. Res. Rev. 2005, 25, 453-472

  • Article • A one-step synthesis of 2-alkyl-5-hydroxychromones and 3-alkoyl-2-alkyl-5-hydroxychromones 

    S. Okombi, J. Schmidt, A-M. Mariotte, E. Perrier, A. Boumendjel

    Chem. Pharm. Bull. 2005, 53, 1460-1462.

  • Article • 2’-Amino-a-chloroacetophenone as a valuable tool for the synthesis of conveniently substituted a,b-epoxychalcones derivatives. 

    M. Blanc.; M. Martin.; S. Okombi and A. Boumendjel

    Chem. Pharm. Bull. 2005, 53, 435-436.

  • Article • Flocculation of colloidal clay by bacterial polysaccharides: effect of macromolecule charge and structure 

    J. Labille, F. Thomas, M. Milas, C. Vanhaverbeke

    J. Coll. Interf. Sc. 2005, 284, 149-156.

  • Article • Antibacterial and antimutagenic activity of extracts and essential oil from Tunisan Pistacia lentiscus 

    N.Hayder, R.Ben Ammar, A.Abdelwahed, S.Kiliani, A.Mahmoud, J.Ben Chibani, AM.Mariotte, K.Ghedira, MG.Dijoux-Franca, L.Chekir-Ghedira.

    Toxicol.Environ.Chem. 2005, 87, 567-573.

  • Article • Antitumor Activity and Distribution of Pyrroloiminoquinones in the Sponge Genus Zyzzya 

    M-G. Dijoux, PC. Schnabel, YF. Hallock, JL. Boswell, TR. Johnson, JA. Wilson, CM. Ireland, R. van Soest, MR. Boyd, LR. Barrows, and JH. Cardellina II.

    Bioorg. Med. Chem. Lett. 2005.

  • Article • Differential effects of cyclodextrins and derivatives on the biological behavior of the myocardial perfusion imaging agent 99mTcN-NOET 

    L. Riou, C. Ghezzi, D. Wouessidjewe, H. Law, J.-P. Mathieu, J. Defaye, R. Bontron, R. Pasqualini, D. Fagret

    Eur. J. Pharm. Biopharm. 2005, 61, 40-49.

  • Article • Piperazinobenzopyranones and phenalkylaminobenzo- pyranones: potent inhibitors of breast cancer resistance protein (ABCG2). 

    A. Boumendjel.; E. Nicolle.; T. Moraux.; B. Gerby.; M. Blanc, X. Ronot and J. Boutonnat

    J. Med. Chem. 2005, 48, 7275-7281.

  • Article • 2’-Amino-a-chloroacetophenone as a valuable tool for the synthesis of conveniently substituted a,b-epoxychalcones derivatives. Chem. Pharm. Bull. 2005, 53, 435-436. 

    M. Blanc.; M. Martin.; S. Okombi and A. Boumendjel.

    Chem. Pharm. Bull. 2005, 53, 435-436.

  • Article • Neamine dimers targeting the HIV-1 TAR RNA. 

    E. Riguet, J. Désiré, O. Boden, V. Ludwig, M. Göbel, C. Bailly, J.-L.Decout

    Bioorg. Med. Chem. Lett. 2005, 15, 4651-4655.

  • Article • Efficient size control of amphiphilic cyclodextrin nanoparticles through a statistical mixture design methodology. 

    L. Choisnard, A. Geze, M. Bigan, J. L. Putaux, D. Wouessidjewe

    J. Pharm. Pharmaceut. Sci. 2005, 8, 593-600

  • Article • Conformational states and thermodynamics of a-lactalbumin bound to membranes: a case study of the effects of pH, calcium, lipid membrane curvature and charge 

    A. Chenal, G. Vernier, P. Savarin, N.A. Bushmarina, A. Geze, F. Guillain, D. Gillet, V. Forge

    J. Mol. Biol. 349, 2005, 890-905

  • Article • Acute toxicity and antioxydant property of Striga hermonthica (Del) Benth (Scrophulariaceae) 

    M. Kiendrebeogo, M.-G. Dijoux-Franca,C-E. Lamien, A. Meda, D. Wouessidjewe, O.-G. Nacoulma.

    African J. Biotechn. 2005, 4, 919-922.

  • Article • New polycyclic diamine scaffolds from dimerization of 3-alkyl-1,4-dihydropyridines in acidic medium. 

    K. Jakubowicz, Y.-S. Wong, A. Chiaroni, M. Bénéchie, C. Marazano.

    J. Org. Chem. 2005, 70, 7780-7783.

  • Patent • Use of aurones for their activity in cosmetic or dermatological compositions 

    S. Okombi, D. Rival, A. Boumendjel, A.-M. Mariotte, E. Perrier

    2005 • Engelhard-Lyon - CNRS - Université de Grenoble I

  • Patent • Utilisation des dérivés de l’acide para-coumarique ou para-hydroxycinnamique dans des compositions cosmétiques ou dermatologiques 

    S. Okombi, D. Rival, A. Boumendjel, A-M. Mariotte, E. Perrier

    2005 • Engelhard Lyon - Université de Grenoble I - CNRS

  • Patent • Pyrazine derivatives and electronic devices using them 

    Schaefer, Thomas; Peuchmaur, Marine; Rogers, Jonathan; Craig, Michael Robert

    2005 • Ciba Specialty Chemicals Holding Inc., Switz.

  • Thesis • Recherche et étude de molécules à activité antityrosinase et leur utilisation comme agents depigmentants en dermocosmétique 

    Sabrina Okombi

    2005 • Thèse soutenue le 21 décembre 2005

  • Thesis • La mucoviscidose : traitements actuels et perspectives thérapeutiques 

    Benjamin Boucherle, Norman Bideau

    2005 • 

  • Article • New flavin and deazaflavin oligonucleotide conjugates for the amperometric detection of DNA hybridization. 

    S. Cosnier, C. Gondran, C. Dueymes, P. Simon, M. Fontecave, J.-L. Decout

    Chem. Commun. 2004, 1624-1625.

  • Article • A route for preparing new neamine derivatives targeting HIV-1 TAR RNA. 

    E. Riguet, J. Desire, C. Bailly, J.-L. Decout

    Tetrahedron 2004, 60, 8053-8064.

  • Article • Streptavidin chiral stationary phase for the separation of adenosine enantiomers 

    C. Ravelet, M. Michaud, A. Ravel, C. Grosset, A. Villet, E. Peyrin

    J. Chromatogr. A 2004, 1036, 155-160.

  • Article • Immobilized DNA aptamers as target-specific chiral stationary phases for resolution of nucleoside and amino acid derivative enantiomers 

    M. Michaud, E. Jourdan, C. Ravelet, A. Villet, A. Ravel, C. Grosset, E. Peyrin

    Anal. Chem. 2004, 76, 1015-1020

  • Article • Synthesis of 6-morpholinyl and 6-piperazinyl-4-alkyl-4H-1,4-benzo-thiazin-3-one derivatives with bacteriostatic activity 

    V.L.M. Guarda, M. Perrissin, F. Thomasson, E.A. Ximenes, S.L. Galdino, I.R. Pitta, C. Luu-Duc

    Heterocyclic communications 2004, 47-52

  • Article • Antimitotic activity of 5-hydroxy-7-methoxy-2-phenyl -4-quinolones 

    M. Hadjeri,E-L. Peiller, C. Beney, N. Deka,M. A. Lawson, C. Dumontet, A. Boumendjel.

    J. Med. Chem. 2004, 47, 4964-4970

  • Article • Sugar-Modified Thionucleosides: Chemistry and Inhibition of Ribonucleotide Reductases and S-Adenosyl-L-Homocysteine Hydrolases. 

    J.-L. Decout, S. F. Wnuk

    Frontiers in Nucleosides and Nucleic Acids Ed. by RF Schinazi and DC Liotta, 2004 IHL Press

  • Article • A peptide nucleic acid-neamine conjugate that targets and cleaves HIV-1 TAR RNA inhibits viral replication. 

    E. Riguet, S. Tripathi, B. Chaubey, J. Desire, V. N. Pandey, J.-L. Decout.

    J. Med. Chem. 2004, 47, 4806-4809.

  • Article • Optimization of the preparation of aqueous suspensions of waxy maize starch nanocrystals using a response surface methodology. 

    H. Angellier, L. Choisnard, S. Molina-Boisseau, P. Ozil, A. Dufresne

    Biomacromolecules 2004, 5, 1545-1551.

  • Article • Optimizing saccharide-directed molecular delivery to biological receptors : design, synthesis, and biological evaluation of glycodendrimer-cyclodextrin conjugates 

    J.-M. Benito, M. Gomez-Garcia, C. Ortiz Mellet, I. Baussanne, J. Defaye, J.-M. Garcia Fernandez

    J. Am. Chem. Soc. 2004, 126, 10355-10363.

  • Article • Enhanced degradation of fluorene in soil slurry by Absidia cylindrospora and maltosyl-cyclodextrin 

    D. Garon, L. Sage, D. Wouessidjewe, F. Seigle-Murandi

    Chemosphere 2004, 56, 159-166.

  • Article • Long term stability study of amphiphilic b-cyclodextrin nanosphere suspensions monitored by dynamic light scattering and cryo-transmission electron microscopy 

    A. Gèze, J.-L. Putaux, L. Choisnard, P. Jéhan, D. Wouessidjewe

    J. Microencapsul. 2004, 21, 607-613.

  • Article • NMR characterization of the interaction between the C-terminal domain of interferon-gamma and heparin-derived oligosaccharides 

    Cecile Vanhaverbeke, Jean-Pierre Simorre, Rabia Sadir , Pierre Gans, Hugues Lortat-Jacob

    Biochem. J. 2004, 384, 93-99.

  • Article • Volatile constituents and biological activity of essential oil of Pistacia lentiscus L. from Tunisia. 

    F. Ben Douissa, L. Chekir-Ghedira, M. Hammani, K. Ghedira, A-M. Mariotte, M-G. Dijoux-Franca,

    Flav.Frag.J,2004, 19, 410-414

  • Book • Frontiers in Nucleosides and Nucleic Acids 

    Sugar-Modified Thionucleosides: Chemistry and Inhibition of Ribonucleotide Reductases and S-Adenosyl-L-Homocysteine Hydrolases.

    J.-L. Decout, S. F. Wnuk

    2004 • 235-266, IHL Press - Tucker (GA), USA

  • Thesis • Modulateur de la MDR bactérienne dans Ligusticum porteri (Apiaceae) et Mirabilis jalapa (Nyctaginaceae) 

    Pascale CEGIELA-CARLIOZ

    2004 • Thèse de l\'UJF (20/04/2004)

  • Thesis • Nouveaux outils pour la coupure et la détection d'ADN 

    Philippe Simon

    2004 • 26 novembre

  • Thesis • Etudes chimique et biologique de Pistacia lentiscus L. 

    Faouzia BEN DOUISSA

    2004 • UniversitŽ J.Fourier 21/12/2004

  • Article • Application of the method of the experimental design to the study of a processing of unshrinkableness of wool fibers 

    L. Choisnard, M. Bigan, D. Blondeau, P. Dhulster, B. Leman, D. Guillochon

    J. Applied Polym. Sci. 2003, 89, 535-547.

  • Article • Use of an amino stationary phase to study the vancomycin dimerization dependence on solute enantioselectivity 

    E. Jourdan, M. Haroun, I. Slama, A. Ravel, C. Grosset, A. Villet, E. Peyrin.

    J. Liq. Chromatogr. Relat. Technol. 2003, 26, 1025-1037

  • Article • Study of tryptophan enantiomer binding to teicoplanin-based stationary phase using perturbation technique. Investigation of the role of sodium perchlorate in solute retention and enantioselectivity 

    B. Loukili, C. Dufresne, E. Jourdan, C. Grosset, A. Ravel A, A. Villet, E. Peyrin

    J. Chromatogr. A 2003, 986, 45-53

  • Article • A DNA aptamer as a new target-specific chiral selector for HPLC 

    M. Michaud, E. Jourdan, A. Villet, A. Ravel, C. Grosset, E. Peyrin

    J. Am. Chem. Soc. 2003, 125, 8672-8679

  • Article • Role of the vancomycin-ristocetin heterodimerization on the enantioselectivity of D, L tryptophan and D, L dansyl tryptophan 

    I. Slama, E. Jourdan, C. Grosset, A, Ravel, A. Villet, E. Peyrin

    J. Chromatogr. B 2003, 795, 115-121

  • Article • Temperature and solute molecular size effects on the retention and enantioselectivity of a series of D, L dansyl amino acids on a vancomycin-based chiral stationary phase 

    I. Slama,E. Jourdan, A. Villet, C. Grosset, A. Ravel, E. Peyrin

    Chromatographia 2003, 58, 399-404

  • Article • A short and simple method for the synthesis of 4,6-dimethoxyazaaurones. 

    M. Lawson, A.-M. Mariotte, A. Boumendjel

    Heterocyclic Commun. 2003, 9, 149-152.

  • Article • Recent Advances in the Synthesis of Conveniently Substituted Flavones, quinolones, chalcones and aurones: Potential biologically active molecules 

    M. Hadjeri, C. Beney, A.-M. Mariotte, A. Boumendjel

    Curr. Org. Chem. 2003, 7, 679-689.

  • Article • Modulation of P-glycoprotein mediated multidrug resistance by flavonoid derivatives 

    M. Hadjeri, M. Barbier, X. Ronot, A.-M. Mariotte, A. Boumendjel, J. Boutonnat

    J. Med. Chem. 2003, 46, 2125-2131.

  • Article • Aurones: A subclass of flavonoids with promising biological potential 

    A. Boumendjel

    Curr. Med. Chem. 2003, 10, 2621-2630

  • Article • Deoxyribonucleoside 2’- or 3’-mixed disulfides: prodrugs to target ribonucleotide reductase and/or to inhibit HIV reverse transcription 

    B. Roy, S. Chambert, M. Lepoivre, A.-M. Aubertin, J. Balzarini, J.-L. Decout

    J. Med. Chem. 2003, 46, 2565-2568

  • Article • Thionucleotides as inhibitors of ribonucleotide reductase 

    B. Roy, S. Chambert, M. Lepoivre, J.-L. Decout

    Nucleosides Nucleotides Nucleic Acids 2003, 22, 883-885.

  • Article • Antioxidant flavonoids and phenolic acids from leaves of Lea guineese G. Don (Leeaceae) 

    P. Op de Beck, G. Cartier, B. David, M.-G. Dijoux-Franca, A.-M. Mariotte

    Phytother. Res. 2003, 17, 345-347.

  • Article • Regioselective sulfonylation at O-2 of cyclomaltoheptaose with 1-(p-tolylsulfonyl)-(1H)-1,2,4-triazole. 

    H. Law, I. Baussanne, J.-M. Garcia Fernandez, J. Defaye.

    Carbohydr. Res. 2003, 338,451-453.

  • Article • Synthesis of new azapenedione oximes 

    H. El From, M.-H. Pera, I. Pitta da Rocha

    Heterocyclic communications 2003, 9, 13-18.

  • Article • Synthesis of 4-octyl-2H-1,4 benzothiazin-3-ones 

    V.L.M. de Guarda, M. Perrissin, F. Thomasson, E.A. Ximenes, S.L. Galdino, I.R. Pitta, C.L. Luu Duc, J. Barbe

    Eur. J. Med. Chem. 2003, 38, 769-773

  • Article • New series of N-substituted phenyl ketone oxime ethers : synthesis and bovine b3-adrenergic agonistic activities 

    A. El Hadri, E. Nicolle, G. Leclerc, F Pietri-Rouxel, A D. Strosberg, Ph. Archimbault

    Pharmazie 2003, 58, 13-17.

  • Article • Synthesis and structural study of arylidene thiazolidine and benzothiazine compounds 

    V.M.Guarda, M.A. Pereira,C.A. De Simone, J.F. Albuquerque, S.L. Galdino, J. Chantegrel, M. Perrissin, C. Beney, F. Thomasson, I.R. Pitta and C. LuuDuc

    Sulfur Lett. 2003, 26, 17-27

  • Article • Hesperitin Esters: Highly Stable Flavanones With Both Free Radical Scavenging and Anti-Elastase Activities 

    A. Boumendjel.; D. Rival.; A-M. Mariotte and E. Perrier.

    Pharm. Biol. 2003, 41, 546-549

  • Article • Unusual Ca2+-Calmodulin Binding Interactions of the Microtubule-Associated Protein F-STOP 

    Denis Bouvier, Cecile Vanhaverbeke, Jean-Pierre Simorre, Gerard J. Arlaud, Isabelle Bally, Vincent Forge, Robert L. Margolis, Pierre Gans, Jean-Philippe Kleman

    Biochemistry 2003, 42, 11484-11493.

  • Article • Conformational Analysis of the Exopolysaccharide from Burkholderia caribensis Strain MWAP71: Impact on the Interaction with Soils 

    Cecile Vanhaverbeke, Alain Heyraud, Karim Mazeau

    Biopolymers 2003, 69, 480-497.

  • Article • Il y a 30 ans, 1973: La synthèse des cryptands 

    J. Defaye

    Encyclopedia Universalis, La Science au Présent, 2003, 281.

  • Patent • Zwitterionic CFTR channel modulators, preparation, pharmaceutical compositions and therapeutic use. 

    J.-L. Decout, C. Routaboul, F. Becq, C. Norez

    2003 • Université Grenoble I / CNRS / Université de Poitiers

  • Patent • Acides nucléiques en tant que nouveaux sélecteurs chiraux spécfiques 

    E. Peyrin, C. Grosset, A. Ravel, A. Villet, E. Jourdan

    2003 • Université de Grenoble I / CNRS

  • Patent • Novel derivatives of cyclodextrins, process for their preparation and their use in particular for solubilizing pharmacologically active substances 

    J. Defaye, C. Ortiz-Mellet, J.M. Garcia-Fernandez, M. Gomez-Garcia, K. Chmurski, J.-X. Yu

    2003 • CNRS / Université de Séville / Université Grenoble 1

  • Patent • Novel cyclodextrin dimers, their preparation and use for solubilizing pharmaceuticals 

    J. Defaye, C. Ortiz-Mellet, J.M. Garcia-Fernandez, J.M. Benito, M. Gomez-Garcia, J.-X. Yu

    2003 • CNRS / Université de Séville / Université Grenoble 1

  • Patent • PNA-neamine conjugates and methods for producing and using the same. 

    J.-L. Decout, V. N. Pandey, E. Riguet

    2003 • University of Medicine and Dentistry of New Jersey, Newark, USA / Université de Grenoble I / CNRS

  • Thesis • Conception, Synthèse et évaluation de l’effet antimitotique des 2-phényl-4-quinolones 

    Mr. Mohamed HADJERI

    2003 • Thèse de l’Université de Grenoble, 12 05 2003

  • Thesis • Nouvelle réaction du méthylglyoxal avec des bases nucléiques et des composés apparentés. Accès à de nouvelles familles d'hétérocycles. 

    Christel Routaboul

    2003 • 31 octobre

  • Thesis • Synthèse et propriétés biologiques de nouveaux dérivés d’un aminoglycoside, la néamine. 

    Emmanuel Riguet

    2003 • 24 octobre 2003

  • Article • A framework based on the extended Wyman concept for analyzing the salt effects on the solute retention in high performance affinity chromatography 

    I. Slama, C. Ravelet, C. Grosset, A. Ravel, A. Villet, E. Nicolle, E. Peyrin

    Anal. Chem. 2002,74, 282-287

  • Article • Stoichiometry and formation constants of six PAHs with gamma-cyclodextrin determined by high performance liquid chromatography using a cyano stationary phase 

    C. Ravelet, A. Ravel, C. Grosset, A. Villet, A. Geze, D. Wouessidjewe, E. Peyrin

    J. Liq. Chromatogr. Relat. Technol. 2002, 25, 421-432

  • Article • A displacement study on vancomycin based-stationary phase using N-acetyl-D-alanine as a competing agent 

    I. Slama, C. Ravelet, C. Grosset, A. Ravel, A. Villet, E. Nicolle, E. Peyrin

    J. Chromatogr. Sci. 2002, 40, 83-86

  • Article • Chromatographic determination of the association constants between nimesulide and native and modified beta-cyclodextrins 

    C. Ravelet, A. Geze, A. Villet, C. Grosset, A. Ravel D. Wouessidjewe, E. Peyrin

    J. Pharm. Biomed. Anal. 2002, 29, 425-429

  • Article • Vancomycin dimerization and chiral recognition studied by high performance liquid chromatography 

    I. Slama, C. Dufresne, E. Jourdan, F. Fahrat, A. Villet, A. Ravel, C. Grosset, E. Peyrin

    Anal. Chem. 2002, 74, 5205-5211

  • Article • Salt effects on the interaction of an amphiphilic model molecule with immobilized phosphatidylcholine monolayers 

    M. Haroun, C. Dufresne, E. Jourdan, A. Ravel, C. Grosset, A. Villet, E. Peyrin

    J. Chromatogr A. 2002, 977, 185-192

  • Article • b-1,4-Linked 2-amino-2-deoxy-D-glucopyranosyl fluoride oligosaccharides; a novel substrate for chitosanase. 

    T. Fukamizo, J. Defaye, D. McIntyre, H.-J. Vogel

    Advan. Chitin Sci. 2002, 6, 125-128.

  • Article • One-step synthesis of non-anomeric sugar isothiocyanates from sugar azides. 

    M.-I. Garcia-Moreno, P. Diaz-Perez,J.-M. Benito, C. Ortiz Mellet, J. Defaye, J.-M. Garcia Fernandez

    Carbohydr. Res. 2002, 337, 2329-2334.

  • Article • New series of aryloxypropanolamines with both human b3-adrenoceptor agonistic activity and free radical scavenging properties. 

    S. Aubriot, E. Nicolle, M. Lattier, C. Morel, W. Cao, K. W. Daniel, S. Collins, G. Leclerc, P.Faure

    Bioorg. Med. Chem. Lett. 2002, 12, 209-212.

  • Article • Multivalent cyclooligosaccharides : versatile-carbohydrate clusters with dual role as molecular receptors and lectin ligands (Revue “Concepts”) 

    C. Ortiz Mellet, J. Defaye, J.-M. Garcia Fernandez

    Chem. Eur. J. 2002, 8, 1983-1990.

  • Article • Recent developments in the synthesis, the chemical modifications and the biological applications of sulfur modified nucleosides, nucleotides and oligonucleotides. 

    S. Chambert, J.-L. Decout

    Org. Prep. Proc. Int. 2002, 34, 27-85.

  • Article • Adenine-aptamer complexes : a bipartite RNA site which binds the adenine nucleic base. 

    M. Meli, J. Vergne, J.-L. Decout, M.C. Maurel

    J. Biol. Chem. 2002, 277, 2104-2111.

  • Article • Fluorescent DNA microarrays using deazaflavin-oligonucleotide probes. 

    C. Dueymes, J.-L. Decout, P. Peltie, M. Fontecave

    Angew. Chem. Int. Ed. 2002, 41, 486-489

  • Article • 2-Trimethylsilylethyl sulfides in the von Braun cyanogen bromide reaction : selective preparation of thiocyanates and application to nucleoside chemistry. 

    S. Chambert, F. Thomasson, J.-L. Decout

    J. Org. Chem. 2002, 67, 1898 - 1904.

  • Article • New stereoselective reaction of methylglyoxal with 2-aminopyridines and adenine derivatives : formation of imino acid-nucleic base derivatives in water under mild conditions. 

    C. Routaboul, L. Dumas, I. Gautier-Luneau, J. Vergne, M.-C. Maurel, J.-L. Decout

    Chem. Commun. 2002, 1114-1115.

  • Article • RNA-acting antibiotics: in vitro selection of RNA aptamers for the design of new bioactive molecules less susceptible to bacterial resistances 

    M.-C. Maurel, B. Biard, C. Moulinier, D. Braz, J. Nugier, I. Chaumas, M. Reboud-Ravaux, J-L. Decout

    J. Pharm. Pharmacol. 2002, 67, 1898-1904 (revue)

  • Article • The 2-(trimethylsilyl)ethyl sulfur group in synthesis 

    S. Chambert, J. Desire, J.-L. Decout

    Synthesis 2002, 16, 2319-2334 (revue)

  • Article • Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters. 

    A. Di Pietro, G. Conseil, J.-M. Pérez-Victoria, G. Dayan, H. Baubichon-Cortay, D. Trompier, J.-M. Jault, de Wet, G. Comte, A. Boumendjel, A.-M. Mariotte, C. Dumontet, D. B. McIntosh, Goffeau, S. Castanys, F. Gamarro, D. Barron.

    Cell. Mol. Life Sci. 2002, 59, 307-322.

  • Article • Acetylated dimethoxyaniline as a key intermediate for the synthesis of aminoflavones and quinolones. 

    N. Deka, M. Hadjeri, M. A. Lawson, C. Beney, A.-M. Mariotte, A. Boumendjel

    Heterocycles 2002, 57, 123-128.

  • Article • 4-Hydroxy-6-methoxyaurones with high-affinity binding to cytosolic domain of P-glycoprotein 

    A. Boumendjel, C. Beney, N. Deka, M. A. Lawson, D. Trompier, H. Baubichon-Cortay, A. Di Pietro

    Chem. Pharm. Bull. 2002, 50, 854-856

  • Article • Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance. 

    A. Boumendjel, A. Di Pietro, C. Dumontet, D. Barron

    Med. Chem. Rev. 2002, 22, 512-529

  • Article • Deacetylation of activated acetophenones with tin(IV) chloride. 

    M. Hadjeri, A.-M. Mariotte, A. Boumendjel

    J. Chem. Res. 2002, 463-464

  • Article • Influence of chemical structure of amphiphilic b-cyclodextrins on their ability to form stable nanoparticles 

    A. Gèze, S. Aous, I. Baussanne, J.-L. Putaux, J. Defaye, D. Wouessidjewe

    Int. J. Pharm. 2002, 242, 301-305.

  • Article • Influence of surfactants on solubility and fungal degradation of fluorene 

    D. Garon, D. Krivobok, D. Wouessidjewe, F. Seigle-Murandi

    Chemosphere 2002, 47,303-309.

  • Article • Kinetic study of the appearance of an antibacterial peptide in the course of bovine haemoglobin peptic hydrolysis 

    L. Choisnard, R. Froidevaux, B. Lignot, N. Nedjar-Arroume, D. Vercaigne-Marko, F. Krier, P. Dhulster, D. Guillochon

    Biotechnol. Appl. Biochem. 2002, 36, 187-194.

  • Article • Advancement in intermediate opioid peptide production in an enzymatic membrane reactor assisted by solvent extraction 

    P. Dhulster, R. Kapel, R. Froidevaux, N. Nedjar-arroume, A. Fertin-Bazus, L. Choisnard, D. Guillochon

    Desalination 2002, 148, 221-226.

  • Article • Synthèse et étude structurale de nouvelles 4-thioxothiazolidin-2-ones substituées 

    J. Chantegrel, J.C. Albuquerque, V.L. Guarda, M. Perrissin, M.C.A. Lima, S.L. Galdino, S.S. Brandao, F. Thomasson, I.R. Pitat, C. LuuDuc

    Ann. Pharm. Fr. 2002, 60, 403-409

  • Thesis • Etude phytochimique et biologique d'une Tiliaceae camerounaise : Christiana africana DC. 

    Laetitia PAYEN-FATTACCIOLI

    2002 • Doctorat de l\'UJF

  • Article • Synthesis and bovine beta-3 adrenergic agonistic activities of a novel series of aryloxypropanolamines 

    A. El Hadri, E. Nicolle, M.-C. Guillaume, G. Leclerc, F. Pietri-Rouxel, A.D. Stroesberg, Ph. Archimbault

    Pharmazie 2001, 56, 517-522.

  • Article • Synthesis of 3-carboxylic derivatives of 1,5-benzodiazepines 

    O. Mansour, B. Szymonski, F. Thomasson, J.-M. Morand, M. Cussac

    J. Heterocycl. Chem. 2001, 38, 641-643

  • Article • Carbohydrate-derived spiroketals. Stereoselective synthesis of di-D-fructose dianhydrides by boron trifluoride promoted glycosylation-spiroketalization of acetal precursors 

    J.-M. Benito, M. Gomez-Garcia, C. Ortiz-Mellet, J.-M. Garcia-Fernandez, J. Defaye

    Org. Lett. 2001, 3, 549-552.

  • Article • Cyclodextrin neoglycoconjugates (Revue) 

    C. Ortiz Mellet, J. Defaye, J.-M. Garcia Fernandez

    Biolog. J. Armenia 2001, 53, 70-81.

  • Article • Dependence of concanavalin A binding on anomeric configuration, linkage type and ligand multiplicity for thiourea-bridged mannopyranosyl- b-cyclodextrin conjugates 

    I. Baussanne, J.-M. Benito, C. Ortiz Mellet, J.-M. Garcia Fernandez, J. Defaye

    ChemBioChem 2001, 10, 777-783.

  • Article • Asymmetric synthesis of 5-substituted pyrrolidinones via a chiral N-acyliminium equivalent 

    I. Baussanne, A. Chiaroni, J. Royer

    Tetrahedron : Asymmetry 2001, 12, 1219-1224.

  • Article • Imino glycals in synthesis : preparation of novel deoxymannojirimycin analogues 

    J. Desire, M. Shipman

    Synlett 2001, 8, 1332-1334

  • Article • Chemistry of Imino glycals : preparation and application to the synthesis of (+)-Fagomine 

    J. Desire, P.-J. Dransfield, P. Gore, M. Shipman

    Synlett 2001, 8, 1329-1331.

  • Article • Synthesis and microbiological activity of some 4-butyl-2H-benzo(1,4)thiazin-3-one derivatives 

    V.-L. de M. Guarda, M. Perrissin, F. Thomasson, E.A. Ximenes, S.-l. Galdino, I.-R. Pitta, C. Luu-Duc

    Il Farmaco 2001, 56, 689-693.

  • Article • An efficient synthesis of 4,6-dimethoxyaurones 

    C. Beney, A.-M. Mariotte, A. Boumendjel

    Heterocycles 2001, 55, 967-972.

  • Article • B-Ring substituted 5,7-dihydroxyflavonols with high-affinity binding to P-glycoprotein responsible for cell multidrug resistance 

    A. Boumendjel, F. Bois, C. Beney, A.M. Mariotte, G. Conseil, A. Di Pietro

    Bioorg. Med. Chem. Lett. 2001, 11, 75-77.

  • Article • Elaboration of new monoterpenoid indole alkaloids containing a dihydrofuran unit 

    A. Boumendjel, J.M. Nuzillard, G. Massiot

    Synlett 2001, 7, 1125-1126

  • Article • Interaction of polyphenolic natural products and synthetic derivatives with P-glycoprotein, a transporter involved in multidrug resistance (MDR): A state of the art. 

    D. Barron, A. Boumendjel, A. Di Pietro, C. Dumontet, D. Mc Intosh

    Anticancer Res. 2001, 21, 1580-1581.

  • Article • Volatile components of Catharanthus roseus (L.) G. Don (Apocynaceae) 

    G. Brun, J.-M. Bessière, M.-G. Dijoux-Franca, B. David, A.-M. Mariotte

    Flavour Fragrance J. 2001, 16, 116-119

  • Article • Xanthones and Other Constituents of Trema orientalis 

    D. Noungoué Tchamo, M.-G. Dijoux-Franca, G. Cartier, E. Tsamo, A.-M. Mariotte

    Pharm. Biol. 2001, 39, 202-205

  • Article • New dihydrophenanthrene and phenylisocoumarin Constituents of Trema orientalis. 

    M.-G. Dijoux-Franca, D. Noungoué Tchamo, B. Cherel, M. Cussac, E. Tsamo, A.-M. Mariotte

    J. Nat. Prod. 2001, 64, 832-835.

  • Article • Alkylation of 2-phenyl-4-quinolones : synthetic and structural studies. 

    M. Hadjeri, A.-M. Mariotte, A. Boumendjel

    Chem. Pharm. Bull. 2001, 49, 1352-1355.

  • Article • Microwave mediated solvent-free acetylation of deactivated and hindered phenols 

    N. Deka, A.-M. Mariotte, A. Boumendjel

    Green Chem. 2001, 3, 263-264

  • Article • Cyclodextrins in pharmaceutical nanoparticles (Revue) 

    D. Duchêne, G. Ponchel, D. Wouessidjewe, A. Bochot

    Biolog. J. Armenia 2001, 53, 125-135.

  • Article • PLGA microsphere bioburden evaluation for radiosterilization dose selection 

    A. Gèze, M.-C. Venier-Julienne, J. Cottin, N. Faisant, J.-P. Benoit

    J. Microencapsul. 2001, 18, 627-636.

  • Article • mROC: a computer program for combining tumour markers in predicting disease states. 

    Kramar A, Faraggi D, Fortune A, Reiser B.

    Computer Methods and Programs in Biomedicine, 2001, 66:199-207

  • Patent • Method and support for biological analysis using oligonucleotides comprising a marker capable of enzymatic activation. 

    J.-L. Decout, M. Fontecave, C. Dueymes

    2001 • CEA / Université de Grenoble I

  • Thesis • Nouvelles méthodes de synthèse de thionucléosides et thionucléotides potentiellement inhibiteurs de la ribonucléotide réductase. 

    Stéphane Chambert

    2001 • Université Joseph Fourier

  • Thesis • Synthèse de conjugués flavine- ou déazaflavine-oligonucléotide. Étude des interactions en double ou triple hélice et de la réduction par la flavine réductase. 

    Cecile Dueymes

    2001 • Université Joseph Fourier

  • Article • Prenylated Xanthones as Potential P-Glycoprotein Modulators 

    D. Noungoué Tchamo, M-G. Dijoux-Franca, A-M. Mariotte, E. Tsamo, J.B. Daskiewicz, C. Bayet, D. Barron, G. Conseil, A. Di Pietro

    Bioorganic and Medicinal Chemistry Letters, 10,2000, 1343-1345

  • Patent • Analysis of biological targets using a biochip comprising a fluorescent marker 

    M. Cuzin, P. Peltie, M Fontecave, J.-L. Decout, C. Dueymes

    2000 • CEA / Université de Grenoble I

  • Patent • Multiparticulate pharmaceutical dosage form. 

    T. Beckert, L. Briand, G. Bergmann, M. Assmus, D. Wouessidjewe

    2000 • Roëhm Pharma Polymers, groupe Degussa

  • Patent • Flavonoid compounds and their use, especially in cosmetics 

    D. Rival, A. Boumendjel, A.-M. Mariotte, E. Perrier

    1999 • Université de Grenoble I

  • Thesis • Etude des constituants chimiques de Catharanthus roseus (L.) G.Don (Apocynaceae) autres que les alcaloïdes 

    Gilles Brun

    1999 • Doctorat de l\'UJF

  • Thesis • Etude phytochimique et biologique de Leea guineensis G.Don (Leeaceae). 

    Philippe Op de Beck

    1999 • Doctorat de l\'UJF

  • Patent • Regioselective method for preparation of C-6 mono-sulfonated cyclodextrins 

    J. Defaye, S. Crouzy, N. Evrard et H. Law

    1998 • CNRS / Université Grenoble 1

  • Thesis • Contribution à l'étude de trema orientalis L. Blume (Ulmaceae) et hémisynthèse de xanthones prénylées. 

    Diderot Noungoué Tchamo

    1998 • Doctorat de l\'UJF

  • Patent • Thioureido-cyclodextrins particularly useful for solubilising antitumoral and antiparasitic agents, and methods for preparing same 

    C. Ortiz-Mellet, J.-M. Garcia Fernandez, J. Defaye

    1996 • CNRS