Benoit CHOVELON

Projets

• Mise au point de dispositifs d'analyse innovants. Ce projet comprend deux volets : d'une part, il s'agit de développer des tests de diagnostic faciles à utiliser, rapides, peu coûteux et/ou portables à l'aide d'aptamères, afin de facilité les soins aux patients ou de détecter les contaminants environnementaux ; d'autre part, l'objectif est d'établir de nouvelles stratégies de signalement pour le développement de dispositifs à haut débit et/ou haute sensibilité.

• Applications hospitalières. Applications hospitalières

Publications

• Article • Stability of fecal calprotectin extracts using the Diasorin® kit [Full paper ]

  B. Billet, L. Choisnard, P. Faure, D. Guicherd, E. Cussigh, E. Peyrin, C. Ravelet, B. Chovelon

  Clin. Chem. Lab. Med. 2024, 62, e13–e15

• Article • Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use [Full paper ]

  R. Goutaudier, F. Joly, D. Mallet, M. Bartolomucci, D. Guicherd, C. Carcenac, F. Vossier, T. Dufourd, S. Boulet, C. Deransart, B. Chovelon, S. Carnicella

  Mol. Psychiatry 2023, 28, 463 74

• Article • S.S. Grp, Phenol and Phthalate Effects on Thyroid Hormone Levels during Pregnancy: Relying on In Vitro Assays and Adverse Outcome Pathways to Inform an Epidemiological Analysis [Full paper ]

  D. Nakiwala, P.D. Noyes, P. Faure, B. Chovelon, C. Corne, A.S. Gauchez, D. Guergour, S. Lyon-Caen, A.K. Sakhi, A. Sabaredzovic, C. Thomsen, I. Pin, R. Slama, C. Philippat

  Environ. Health Perspect. 2022, 130, 117004

• Article • Biodriven investigation of the wild edible mushroom Pleurotus eryngii revealing unique properties as functional food [Full paper ]

  S. Teniou, A. Bensegueni, B.M. Hybertson, B. Gao, S.K. Bose, J.M. McCord, B. Chovelon, C. Bensouici, A. Boumendjel, I. Hininger-Favier

  J. Funct. Foods., 2022, 89, 104965

• Article • Stability of catecholamines in whole blood: Influence of time between collection and centrifugation [Full paper ]

  Q. Despinasse, L. Choisnard, P. Faure, D. Guicherd, E. Peyrin, C. Ravelet, B. Chovelon

  Clin. Chem. Lab. Med. 2021, 59, e83 85

• Article • Preclinical Evaluation of Sodium Selenite in Mice: Toxicological and Tumor Regression Studies after Striatum Implantation of Human Glioblastoma Stem Cells [Full paper ]

  L. Larrouquère; S. Berthier; B. Chovelon; C. Garrel; V. Vacchina; H. Paucot; J. Boutonnat; P. Faure; F. Hazane-Puch

  Int. J. Mol. Sci. 2021, 22, 10646

• Article • Theranostic AGuIX Nanoparticles as Radiosensitizer: A Phase I, Dose-Escalation Study in Patients with Multiple Brain Metastases (NANO-RAD Trial) 

  C. Verry, S. Dufort, J. Villa, M. Gavard, C. Iriart, S. Grand, J. Charles, B. Chovelon, J.-L. Cracowski, J.-L. Quesada, C. Mendoza, L. Sancey, A. Lehmann, F. Jover, J.-Y. Giraud, F. Lux, Y. Crémillieux, S. McMahon, P. J. Pauwels et al

  Radiother. Oncol. 2021, 160, 159 165

• Article • Iodinated Organic Molecule as Tag for Inductively Coupled Plasma-Mass Spectrometry Aptamer Assays [Full paper ]

  B. Billet, B. Chovelon, E. M. McConnell, D. André, L. Puillet-Anselme, E. Fiore, P. Faure, C. Ravelet, M. C. DeRosa, E. Peyrin

  Talanta, 2024, 267, 125107

• Article • Non-Competitive Determination of Small Analytes by Sandwich-type Lateral Flow Assay based on Aptamer Kissing Complex [Full paper ]

  B. Chovelon, V. Ranganathan, S. Srinivasan, E. McConnell, P. Faure, E. Fiore, C. Ravelet, E. Peyrin, M. DeRosa

  Anal. Chem. 2024, 96, 18, 6875-6880

• Article • Nile blue as reporter dye in salt aggregation based-colorimetric aptasensors for peptide, small molecule and metal ion detection [Full paper ]

  B. Chovelon, E. Peyrin, M. Ragot, N. Salem, T. Giang Nguyen, B. Auvray, M. Henry, M-A Petrillo, E. Fiore, Q. Bessy, P. Faure, C. Ravelet

  Anal. Chim. Acta, 2023, 1243, 340840

• Article • Detection of Small Molecules by Fluorescence Intensity using Single Dye Labeled Aptamers and Quencher Transition Metal Ions [Full paper ]

  B. Billet, B. Chovelon, E. Fiore, P. Faure, C. Ravelet, E. Peyrin

  Biosens. Bioelectron. 2022, 205, 114091

• Article • ATP7B-Deficient Hepatocytes Reveal the Importance of Protein Misfolding Induced at Low Copper Concentration [Full paper ]

  P. Charbonnier, B. Chovelon, C. Ravelet, T. D. Ngo, M. Chevallet and A. Deniaud

  Cells, 2022, 11, 3400

• Article • Aptamer Switches Regulated by Post-Transition/Transition Metal Ions [Full paper ]

  B. Billet, B. Chovelon, E. Fiore, F. Oukacine, M-A Petrillo, P. Faure, C. Ravelet, E. Peyrin

  Angew. Chem. Int. Ed. 2021, 60, 12346–12350

• Article • Anti-pesticide DNA aptamers fail to recognize their targets with asserted micromolar dissociation constants [Full paper ]

  L. Zara, S. Achilli, B. Chovelon, E. Fiore, J.J Toulmé, E. Peyrin, C. Ravelet,

  Anal. Chim. Acta 2021, 1159, 338382

• Article • Exposure to a Mixture of Non-Persistent Environmental Chemicals and Neonatal Thyroid Function in a Cohort with Improved Exposure Assessment  [Full paper ]

  O. Coiffier, D. Nakiwala, M. Rolland, A. Malatesta, S. Lyon-Caen, B. Chovelon, P. Faure, A. S. Gauchez, D. Guergour, A. K. Sakhi, A. Sabaredzovic, C. Thomsen, I. Pin, R. Slama, C. Corne, C. Philippat

  Environ. Int. 2023, 173, 107840

• Article • Intracellular accumulation and immunological response of NIR-II polymeric nanoparticles [Full paper ]

  I. Moskalevska, V. Faure, L. Haye, M. Mercey-Ressejac, A. K. Dey, B. Chovelon, L. K. Soro, L. J. Charbonnière, A. Reisch, A. S. Klymchenko, P. N. Marche, J.-L. Coll, Z. Macek Jilkova, X. Le Guévuel

  Int. J. Pharm. 2023, 630, 122439

• Article • A Cobalt Oxide–Polypyrrole Nanocomposite as an Efficient and Stable Electrode Material for Electrocatalytic Water Oxidation [Full paper ]

  D. V. Morales, C. N. Astudillo, V. Anastasoaie, B. Dautreppe, B. F. Urbano, B. L. Rivas, C. Gondran, D. Aldakov, B. Chovelon, D. André, J.-L. Putaux, C. Lancelon-Pin, S. Sirach, E.-M. Ungureanu, C. Costentin, M.-N. Collomb, J. Fortage

  Sustainable Energy Fuels 2021, 5, 4710 4723

• Article • Influence of delayed separation of plasma from whole blood & centrifugation protocol on Zn plasma concentration [Full paper ]

  M. Leger, Q. Despinasse, P. Faure, J. Arnaud, C. Ravelet, B. Chovelon

  Clin Chem Lab Med e279-e281