Benoit CHOVELON

Projets

• Mise au point de dispositifs d'analyse innovants. Ce projet comprend deux volets : d'une part, il s'agit de développer des tests de diagnostic faciles à utiliser, rapides, peu coûteux et/ou portables à l'aide d'aptamères, afin de facilité les soins aux patients ou de détecter les contaminants environnementaux ; d'autre part, l'objectif est d'établir de nouvelles stratégies de signalement pour le développement de dispositifs à haut débit et/ou haute sensibilité.

• Applications hospitalières. Applications hospitalières

Publications

• Article • Stability of fecal calprotectin extracts using the Diasorin® kit [Full paper ]

  B. Billet, L. Choisnard, P. Faure, D. Guicherd, E. Cussigh, E. Peyrin, C. Ravelet, B. Chovelon

  Clin. Chem. Lab. Med. 2024, 62, e13–e15

• Article • Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use [Full paper ]

  R. Goutaudier, F. Joly, D. Mallet, M. Bartolomucci, D. Guicherd, C. Carcenac, F. Vossier, T. Dufourd, S. Boulet, C. Deransart, B. Chovelon, S. Carnicella

  Mol. Psychiatry 2023, 28, 463 74

• Article • S.S. Grp, Phenol and Phthalate Effects on Thyroid Hormone Levels during Pregnancy: Relying on In Vitro Assays and Adverse Outcome Pathways to Inform an Epidemiological Analysis [Full paper ]

  D. Nakiwala, P.D. Noyes, P. Faure, B. Chovelon, C. Corne, A.S. Gauchez, D. Guergour, S. Lyon-Caen, A.K. Sakhi, A. Sabaredzovic, C. Thomsen, I. Pin, R. Slama, C. Philippat

  Environ. Health Perspect. 2022, 130, 117004

• Article • Biodriven investigation of the wild edible mushroom Pleurotus eryngii revealing unique properties as functional food [Full paper ]

  S. Teniou, A. Bensegueni, B.M. Hybertson, B. Gao, S.K. Bose, J.M. McCord, B. Chovelon, C. Bensouici, A. Boumendjel, I. Hininger-Favier

  J. Funct. Foods., 2022, 89, 104965

• Article • Stability of catecholamines in whole blood: Influence of time between collection and centrifugation [Full paper ]

  Q. Despinasse, L. Choisnard, P. Faure, D. Guicherd, E. Peyrin, C. Ravelet, B. Chovelon

  Clin. Chem. Lab. Med. 2021, 59, e83 85

• Article • Preclinical Evaluation of Sodium Selenite in Mice: Toxicological and Tumor Regression Studies after Striatum Implantation of Human Glioblastoma Stem Cells [Full paper ]

  L. Larrouquère; S. Berthier; B. Chovelon; C. Garrel; V. Vacchina; H. Paucot; J. Boutonnat; P. Faure; F. Hazane-Puch

  Int. J. Mol. Sci. 2021, 22, 10646

• Article • Theranostic AGuIX Nanoparticles as Radiosensitizer: A Phase I, Dose-Escalation Study in Patients with Multiple Brain Metastases (NANO-RAD Trial) 

  C. Verry, S. Dufort, J. Villa, M. Gavard, C. Iriart, S. Grand, J. Charles, B. Chovelon, J.-L. Cracowski, J.-L. Quesada, C. Mendoza, L. Sancey, A. Lehmann, F. Jover, J.-Y. Giraud, F. Lux, Y. Crémillieux, S. McMahon, P. J. Pauwels et al

  Radiother. Oncol. 2021, 160, 159 165

• Article • Iodinated Organic Molecule as Tag for Inductively Coupled Plasma-Mass Spectrometry Aptamer Assays 

  B. Billet, B. Chovelon, E. M. McConnell, D. André, L. Puillet-Anselme, E. Fiore, P. Faure, C. Ravelet, M. C. DeRosa, E. Peyrin

  Talanta, 2024, 267, 125107

• Article • Non-Competitive Determination of Small Analytes by Sandwich-type Lateral Flow Assay based on Aptamer Kissing Complex 

  B. Chovelon, V. Ranganathan, S. Srinivasan, E. McConnell, P. Faure, E. Fiore, C. Ravelet, E. Peyrin, M. DeRosa

  Anal. Chem., 2024, 10.1021/acs.analchem.3c05472

• Article • Nile blue as reporter dye in salt aggregation based-colorimetric aptasensors for peptide, small molecule and metal ion detection [Full paper ]

  B. Chovelon, E. Peyrin, M. Ragot, N. Salem, T. Giang Nguyen, B. Auvray, M. Henry, M-A Petrillo, E. Fiore, Q. Bessy, P. Faure, C. Ravelet

  Anal. Chim. Acta, 2023, 1243, 340840

• Article • Detection of Small Molecules by Fluorescence Intensity using Single Dye Labeled Aptamers and Quencher Transition Metal Ions 

  B. Billet, B. Chovelon, E. Fiore, P. Faure, C. Ravelet, E. Peyrin

  Biosens. Bioelectron. 2022, 205, 114091

• Article • ATP7B-Deficient Hepatocytes Reveal the Importance of Protein Misfolding Induced at Low Copper Concentration [Full paper ]

  P. Charbonnier, B. Chovelon, C. Ravelet, T. D. Ngo, M. Chevallet and A. Deniaud

  Cells, 2022, 11, 3400

• Article • Aptamer Switches Regulated by Post-Transition/Transition Metal Ions [Full paper ]

  B. Billet, B. Chovelon, E. Fiore, F. Oukacine, M-A Petrillo, P. Faure, C. Ravelet, E. Peyrin

  Angew. Chem. Int. Ed. 2021, 60, 12346–12350

• Article • Anti-pesticide DNA aptamers fail to recognize their targets with asserted micromolar dissociation constants [Full paper ]

  L. Zara, S. Achilli, B. Chovelon, E. Fiore, J.J Toulmé, E. Peyrin, C. Ravelet,

  Anal. Chim. Acta 2021, 1159, 338382

• Article • Exposure to a Mixture of Non-Persistent Environmental Chemicals and Neonatal Thyroid Function in a Cohort with Improved Exposure Assessment  [Full paper ]

  O. Coiffier, D. Nakiwala, M. Rolland, A. Malatesta, S. Lyon-Caen, B. Chovelon, P. Faure, A. S. Gauchez, D. Guergour, A. K. Sakhi, A. Sabaredzovic, C. Thomsen, I. Pin, R. Slama, C. Corne, C. Philippat

  Environ. Int. 2023, 173, 107840

• Article • Intracellular accumulation and immunological response of NIR-II polymeric nanoparticles [Full paper ]

  I. Moskalevska, V. Faure, L. Haye, M. Mercey-Ressejac, A. K. Dey, B. Chovelon, L. K. Soro, L. J. Charbonnière, A. Reisch, A. S. Klymchenko, P. N. Marche, J.-L. Coll, Z. Macek Jilkova, X. Le Guévuel

  Int. J. Pharm. 2023, 630, 122439

• Article • A Cobalt Oxide–Polypyrrole Nanocomposite as an Efficient and Stable Electrode Material for Electrocatalytic Water Oxidation [Full paper ]

  D. V. Morales, C. N. Astudillo, V. Anastasoaie, B. Dautreppe, B. F. Urbano, B. L. Rivas, C. Gondran, D. Aldakov, B. Chovelon, D. André, J.-L. Putaux, C. Lancelon-Pin, S. Sirach, E.-M. Ungureanu, C. Costentin, M.-N. Collomb, J. Fortage

  Sustainable Energy Fuels 2021, 5, 4710 4723

• Article • Influence of delayed separation of plasma from whole blood & centrifugation protocol on Zn plasma concentration [Full paper ]

  M. Leger, Q. Despinasse, P. Faure, J. Arnaud, C. Ravelet, B. Chovelon

  Clin Chem Lab Med e279-e281